YoshiTrainer said:

(Left is natalensis right is ochraceocentrata)

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Fruit 🍑 pictures:

YoshiTrainer said:

Natalensis

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PhenoDreamers said:

Here are true natalensis gills

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So Anyway said:

Since this is on page one and therefore easy to find, can someone explain the Ochra/Nats split? I'd do it because I'm absolutely 100% up to date with all shroom info and lore but kinda busy over here and I actually have no idea

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tree frog said:

potato11teen said:

And yet, are we really able to call anything true Nats, or even true Ochres? Has anyone done sequencing? Would the sequencing data even be accurate because what the mycologists have been calling Natalensis isn't Natalensis. Where's the microscopy?

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Ps. Natelensis was an already described and sequenced species.  Folks found a new species they assumed was Natelensis.  Spores were dispersed under that name.  Folks grew it under that name.  And a few months ago, several samples of the new species were sequenced and it was discovered that the new species was never Ps. Natelensis.

And yes people have looked at the spores. The mycelium itself is also very different, ochra loves to go rhizo.  Nats form true sclerotia.

There's a ton of shots of ochra already but here's some photo of nat mycelium.







And the fruit bodies look different too, but I haven't fruited any yet.

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So Anyway said:

Since this is on page one and therefore easy to find, can someone explain the Ochra/Nats split? I'd do it because I'm absolutely 100% up to date with all shroom info and lore but kinda busy over here and I actually have no idea

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Quote:

Psilocybin-containing mushrooms, commonly known as magic mushrooms, have been used since ancient and recent times for depression and to improve quality of life. However, their anti-inflammatory properties are not known. The study aims at investing cytotoxicity; antioxidant; and, for the first time, anti-inflammatory effects of Psilocybe natalensis, a psilocybin-containing mushroom that grows in South Africa, on lipopolysaccharide-induced RAW 264.7 macrophages.

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Quote:

Anti-Inflammatory Effects of Four Psilocybin-Containing Magic Mushroom Water Extracts in vitro on 15-Lipoxygenase Activity and on Lipopolysaccharide-Induced Cyclooxygenase-2 and Inflammatory Cytokines in Human U937 Macrophage Cells

Results: The four water extracts had poor 15-LOX inhibition activity with IC50 > 250 µg/mL. Extracts were safe at the concentration studied and inhibited the LPS-induced production of pro-inflammatory mediators, TNF-α and IL-1β significantly and lowered IL-6 and COX-2 concentrations in treated human U937 macrophage cells. Water extracts also increased percentage viability of treated cells and levels of anti-inflammatory IL-10 non-significantly.

Conclusion: The study suggested that the hot-water extracts of the four psilocybin-containing magic mushrooms have potential anti-inflammatory effects executed by down-regulating pro-inflammatory mediators.

Keywords: 15-LOX; COX-2; Panaeolus cyanescens; Psilocybe cubensis; Psilocybe cubensis A+ strain; Psilocybe natalensis; pro-inflammatory cytokine.

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