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Re: I may have discovered something... [Re: WillieTomg]
    #4868111 -

I have two theories on this. First, the acidic juice frees the actives from the powder better/faster than just water alone. Also, I know for sure that altering the ph of your stomach or urine will definitely affect the speed/level of absorption for many drugs. It might be an interesting experiment for someone with the equipment to see if maybe some of the psilocybin is breaking down into psilocin.

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Re: Theories for how this potentiation works [Re: yousuck]
    #4868140 -

Also, grapefruit juice may have an added effect over some other juices as it has an inhibiting effect on a part of the CYP 3A enzyme in the digestive system, preventing substrates of this enzyme from being metabolized. See Grapefruit Juice and Drug Interactions
Also useful is: CYP-P450 Drug Interactions


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-"Freedom in America is nothing more than an illusion created by the government to keep it's people pacified as it takes away more of our rights." -`NoTiCRusH

Edited by NoTiC (10/29/05 09:43 PM)

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Re: Theories for how this potentiation works [Re: NoTiC]
    #4869623 -

I ate n 8th either 4-5 hours ago. I'm not to sure because I think the time changed. I squeezed a lemon into the 8th of mushrooms then topped it off with orange juice and I've never tripped so hard.

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Re: Theories for how this potentiation works [Re: MushroomMonster]
    #4870297 -

Notic, both of your ideas have been discussed in the many pages of this thread hehe.  I know its a lot to read sorry.  My working theory is that all those factors are contributing.  The low pH starts the psylocin conversion process, so you have ready to absorb psylocin as soon as you drink.  Being powdered in solution increases the surface area that is available for absorption.  And while it hasn't been studies as in depthly, lemon looks like it may have many of the same enzyme inhibiting factors as grapefuit.  Things that mess with these enzymes affect absorption.  Most notably 'first pass' absorption.  If all 3 of these factors are affecting absorption in the same direction(i.e. more psylocin absorbed over a shorter period of time), then that could very well explain everything hehe.  I went into all this in more depth somewhere in middle of this thread, but that is the jist of what I think is going on. 

I am glad so many have tried or are going to try the lemon.  For those that are having effects similar to me, you can understand why I started the thread in the first place :smile:


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If you cut off my head, what would I say? Me and my head, or me and my body?

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Re: Theories for how this potentiation works [Re: Underhillmaster]
    #4870550 -

ok heres how it went
12:19am dose
12:30am initial feeling
12:45am first visuals
1:09am trip begins
the come up was quick and there was no stomach feeling at all. my head got light fast and the body feeling came on quick as well. i was at level 3 at peak and had some nice visuals then they tapered off by about 2:30am then from there it was more philosophical. i went to sleep by 4:00am with an afterglow feeling. juice wasn't refrigerated during the soak which was for just over 11 hrs. i will note that i have tripped the past few weekends straight and my tolerance has built up. I'm going to wait at least a month before next trip, not only to get normal tolerance back but to conserve my mushrooms as well since the cube season is done here in my part of georgia. we can only hope for good weilii flushes now. next time i'll dose more, probably at least 4-5g with the juice next time. i will say though, i wouldn't have been able to get what i got out of that trip if i had just eaten them. the juice worked. hopefully next trip will be longer. try it if you haven't yet.

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Re: Theories for how this potentiation works [Re: hilikus989]
    #4871327 -

Well it seems that it's worked for almost everybody so far, except for an exception or two. I noticed that at least two of the exceptions (I didn't read the entire thread, skipped a few pages here and there) put the lemon juice in the fridge to let it soak. Since heat speeds up chemical reactions, it's easy to assume lack of heat would slow them down. So do NOT refridgerate your juice or fresh fruit if you're going to try this method. Or at least take them out of the fridge a few hours in advance so they have time to reach room temperature.

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Re: I may have discovered something... [Re: snakeandbake]
    #4872833 -

Nice way to overdose, I exhibited the same feeling when I OD'd on X, and my thoughts were to fast for me, I was thinking so fast I couldn't remember shit that I said 30 seconds ago. My brain felt like a guy on Crystal Meth and Crack screaming:


GO-GO-GO-GO-GO-GO-GO-GO-GO-GO-GO-GO-GO-GO!


Near Death Experience right there, you my friend seems like almost died too, you just don't even realize it.

If you injected THC straight in your brain with a syringe you may/could die, it's all about the method of absorbtion.

Drinking juice and taking shroomz could just be THAT syringe that cannot be controlled. Catch my drift.

Injecting heroin is more effective too, healthier...no


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?Tech N9NE the craziest - forget the rest.?

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Re: I may have discovered something... [now a community experiment - please contribute] [Re: slammin007]
    #4873748 -

slammin007 said:
OK, I was excited about this, although I've never felt any benefits from mixing shrooms in any way with any substance.  I thought I'd give it a try.

I'd consider myself fairly experienced with shrooms, I've tripped about 100 times.  I know what each level feels like and what to expect. 


I used 3 fresh limes and 1 gram of shrooms which I placed in the juice and blended with the braun mixer for about a minute.  I placed the juice in the fridge and let it sit for an hour. 

I didn't feel any effects stronger than a 1.0 gram usually gives me.

I also hadn't eaten for about 4 hours and hadn't done any drugs for 7 days prior.

So, I just thought I'd report, it didn't work for me.



The other user in the thread that posted it didn't work for him.. also put it in the fridge prior to drinking it... interesting.  :shocked:


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Re: I may have discovered something... [now a community experiment - please contribute] [Re: nonphixion]
    #4874554 -

This is great. Thank you Underhillmaster, and all contributors! I have read all pages and I`m eager to join the experiment as well as to find out whats going on and what are perfect conditions for this to work.

So far I`v been asking myself: does it just not always work (not for everyone, but most) or did those people who had no potentiating results did something wrong? There were, as mentioned, two cases of putting juice in the fridge (makes sense that it would not work so good) and also some of the reports with no results (if I remember) were not detailed, not stating if the juice was fresh, from bottle 100% or weaker.

So I believe it would be best if people doing it were giving as much info as possible. Now, as for placebo...  I know it can have big effects; I once had blotter that was empty, but believed it was just weak and was feeling something out of ordinary....  Bot still I don`t think it could have such an effect - in his original post Underhillmaster had most powerful mushroom trip in his 20 year tripping experience, from just 2g - more powerful than his other ~10g experiences! BUT...

..I can not forget what I have read here, I am influenced, yes, BUT my two friends are not and at least one of them is willing to try it. I told him its Shroomery experiment, I told him it will probably have influence on his/their trip but I said nothing how, I only said it can be anything, strength, length, visual aspect, body load of a trip, or 100 other things so just notice what (if at all) is different from your normal trip from such dosage (around 0.5g). As soon as he/they`ll do it I`ll report back. As for me, I have just two days ago tripped in autumn forest and it was great but I will have to wait some time before trying this.

What else can I say - lets keep it alive and hope in time we will understand this better - or at least understand what works. Good luck to all and this experiment. And happy tripping :smile:


--------------------
Who looks outside, dreams; who looks inside, awakes.
- Carl Gustav Jung

Edited by Psiledehysp (10/31/05 10:07 AM)

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Re: I may have discovered something... [Re: NoTiC]
    #4875087 -

NoTiC said:
I have two theories on this. First, the acidic juice frees the actives from the powder better/faster than just water alone. Also, I know for sure that altering the ph of your stomach or urine will definitely affect the speed/level of absorption for many drugs. It might be an interesting experiment for someone with the equipment to see if maybe some of the psilocybin is breaking down into psilocin.



your body breaks down psilocybin into psilocin through metabolism anyway. psilocybin is a more stable molecule than psilocin. so  maybe since the acidic juices are  doing  this before it's consumed it allows the body to absorb more psilocin, faster, before it is destroyed by monoamineoxidase. maybe it's a short acting MAOI which would allow more psilocin absorbtion as well?

lemmon juice, cranberry juice, and vinegar (acidic) are also used in making home ayahuasca brews and DMT,as well as psilocybin extractions. since all of these are tryptamine maybe that will shed some light onto why people seem to be having very strong effects from smaller doses?

or maybe i'm just imagining all of this? :smirk:


--------------------
let it be know, there is a fountain that was not made by the hands of men.

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Re: I may have discovered something... [Re: fungusflip]
    #4875106 -

fungusflip said:
NoTiC said:
I have two theories on this. First, the acidic juice frees the actives from the powder better/faster than just water alone. Also, I know for sure that altering the ph of your stomach or urine will definitely affect the speed/level of absorption for many drugs. It might be an interesting experiment for someone with the equipment to see if maybe some of the psilocybin is breaking down into psilocin.



your body breaks down psilocybin into psilocin through metabolism anyway. psilocybin is a more stable molecule than psilocin. so  maybe since the acidic juices are  doing  this before it's consumed it allows the body to absorb more psilocin, faster, before it is destroyed by monoamineoxidase. maybe it's a short acting MAOI which would allow more psilocin absorbtion as well?

lemmon juice, cranberry juice, and vinegar (acidic) are also used in making home ayahuasca brews and DMT,as well as psilocybin extractions. since all of these are tryptamine maybe that will shed some light onto why people seem to be having very strong effects from smaller doses?

or maybe i'm just imagining all of this? :smirk:



how wierd! i said almost the exact same thing as "Underhillmaster" said in response to the same post by "NoTiC", without even realizing it til now. goes to show that some of us are on the same page. :wink:

Edited by fungusflip (10/31/05 12:30 PM)

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Re: I may have discovered something... [Re: fungusflip]
    #4879364 -

i must try it...

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Re: I may have discovered something... [Re: strangladesh]
    #4881405 -

Quote:
Quote:
fungusflip said:

Quote:
NoTiC said:
I have two theories on this. First, the acidic juice frees the actives from the powder better/faster than just water alone. Also, I know for sure that altering the ph of your stomach or urine will definitely affect the speed/level of absorption for many drugs. It might be an interesting experiment for someone with the equipment to see if maybe some of the psilocybin is breaking down into psilocin.



your body breaks down psilocybin into psilocin through metabolism anyway. psilocybin is a more stable molecule than psilocin. so maybe since the acidic juices are doing this before it's consumed it allows the body to absorb more psilocin, faster, before it is destroyed by monoamineoxidase. maybe it's a short acting MAOI which would allow more psilocin absorbtion as well?

lemmon juice, cranberry juice, and vinegar (acidic) are also used in making home ayahuasca brews and DMT,as well as psilocybin extractions. since all of these are tryptamine maybe that will shed some light onto why people seem to be having very strong effects from smaller doses?

or maybe i'm just imagining all of this?



how wierd! i said almost the exact same thing as "Underhillmaster" said in response to the same post by "NoTiC", without even realizing it til now. goes to show that some of us are on the same page.




The reason for Lemon being used in dmt brews is the simple fact that it acidifies the water, allowing for the dmt to precipitate out as a salt. When you basify the same solution, it turns the dmt into a freebase. Thats why when you use an acid/base extraction, the dmt will not leave the solution in a nonpolar solvent when its acidic.
So you can defat the solution for a cleaner extract.

Its not because its a MAOI! Caapi(sp?) the vine used in most aya brews has a MAOI in it, not the lemon. Personally, I think the primary reason for the strength of the lemon mushroom, is the simple fact that its pulling out the goodies before that happens in your stomach. Meaning your going to get a stronger wave initally, and it will be finished faster. Basic Chemistry.

The reason its probably been stronger than mushroom tea, is because most of your preparations are not involving so much heat; thereby the psyliocin is not being broken down.
Cleaner extract, less material plus more surface area = Stronger Faster Trip.

You'll notice the biggest difference most likely, if up to this point you have only been eating the mushrooms whole, or making tea with too hot a liquid.
But I would say its defanitly not entirely placebo.

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Re: I may have discovered something... [Re: RussianCelery]
    #4887555 -

this method sure would save me money/time! :smile:


--------------------
"How could this poison be the dream of my soul...I let my fantasy take complete control." -Black Sabbath "megalomania"

***************
Double Tub Tek Pictorial

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Re: I may have discovered something... [Re: rod]
    #4887561 -

rod said:
I,ve been chopping mine up and adding to juice for a long time,
I,m going to get some pompom cranberry juice for my next time I think :thumbup: [/quoteI

I thought pompom only had pomegranate and grape juice?


--------------------
"How could this poison be the dream of my soul...I let my fantasy take complete control." -Black Sabbath "megalomania"

***************
Double Tub Tek Pictorial

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Re: I may have discovered something... [Re: Underhillmaster]
    #4892511 -

Fucking riiighhhht!

I tripped on .8 grams for 5 hours and am still feeling the after effects! Poured straight lemon juice in a shotglass, let the powdered shrooms sit in there for about 5 minutes, then slammed it, and drank another shot of lemon juice.

Onset in about half an hour, elevated mood, fantastic trip for the amount of boomers eaten!

:teleport:


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010001100100001001000101!

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Re: I may have discovered something... [Re: Fospher]
    #4892576 -

Fospher,

You bought concentrated lemon juice like you can get from the store, correct? You didn't actually squeeze lemons?


I just spent the last 4 hours or so reading this post (and doing my homework) when I should reallllly be sleeping. Awesome work! This is a pretty incredible discovery. Even if it doesn't work for everybody it's really pretty exciting. I'm going to try this with a friend this weekend. He's never tripped before though so I'm debating how much to give him...

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Re: I may have discovered something... [Re: peepants]
    #4892967 -

ive been offline for a while. my computer died of several virus' and virulent wear.
3 nights ago i split up 8 grams of powedered liberty caps among 2 friends after letting it sit in cranberry juice.


it was there first time. it wans't a good idea.

they both started floating in a half hour and really started to wig on the shrooms. then they were both puking their guts out.

they only puked for a minute but this started a thought loop of doom that had them in the bathroom for hours talking about calling the paramedics. yeesh.

i kept assuring them that they would be alright. but the girl was getting red patches on her body and claimed she could not breathe. by about a half hour she was in a dead weight and could not will her body to move. she COULD breathe just fine of course, she was in fact hyperventilating. her crying would be inturrupted withtg the occasional blood-curdling wail of anguish. her BF pretty much just sat there asking "is this normal?" over and over.
it was a disaster.
i was also tripping quite profoundly, and could see the mechanisms of their anguish. i however, more experienced, was used to it. i thought however in my experience i could coach neophytes through it. i was mistaken.
all i could do pretty much was carry the girl to a warmer spot and comfort the guys worries about his girlfriend.
the guy kept complaining of triangles.

dispite the mayhem and fear, evrybody was smiling and going into fits of laughter occasionally. thats good at least, tho far from a visionary experience. i had about 3 grams so i could be a bit of ground support, but it was too much, i cant immagine how intense it was for them.

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Re: I may have discovered something... [Re: peepants]
    #4893430 -

peepants said:
Fospher,

You bought concentrated lemon juice like you can get from the store, correct? You didn't actually squeeze lemons?



This shit that I got is just like the real thing though, though Im pretty sure as long as you maintain the same acidity, it doesnt matter.


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010001100100001001000101!

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Re: I may have discovered something... [Re: Fospher]
    #4895146 -




A friend and I used this kind of supermarket lemon juice and got 2-3 potentiation on mixing the shrooms with 25ml and letting it steep for 5min.


--------------------
Omnicyclion.org
personal empowerment for the world

:nyan: LGBT - Love God Before Tradition :nyan:

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