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InvisibleDiploidM
Cuban

Folding@home Statistics
Registered: 01/09/03
Posts: 19,274
Loc: Rabbit Hole
Evidence For The Scientific Validity Of The Concept Of Race
    #4312585 - 06/19/05 01:39 AM (11 years, 5 months ago)

http://www.kansascity.com/mld/kansascity/news/nation/11913773.htm

Drug for specific race gets first-round OK

The Associated Press

WASHINGTON ? Government advisers on Thursday recommended approval of what could be the first drug aimed at a specific racial group.

The Food and Drug Administration's cardiovascular drug advisory panel voted 9-0 in favor of allowing sales of the heart failure drug BiDil.

A clinical trial of the drug in black Americans was halted early when it became apparent that those using the drug did better than those not using it.

That trial, on just over 1,000 individuals, was launched after the FDA turned away the drug following a study involving all races that showed little improvement ? but also gave hints that black patients might have had some benefit.

The maker, NitroMed of Lexington, Mass., then decided on a trial using blacks only, a population that has more than twice the rate of heart failure as whites.

In heart failure, the heart is too weak to beat effectively and fluid builds up in the lungs. As many as half of all victims die within five years.

The usual treatment is with drugs called ACE inhibitors, but research has indicated they do not work as well in black patients as in white patients.

BiDil is a combination of two drugs: hydralazine, which eases blood pressure, and isosorbide dinitrate, which is used for heart pain. The combination also boosts the amounts of nitric oxide in the blood, a substance that is found in lower levels in blacks.


--------------------
Republican Values:

1) You can't get married to your spouse who is the same sex as you.
2) You can't have an abortion no matter how much you don't want a child.
3) You can't have a certain plant in your possession or you'll get locked up with a rapist and a murderer.

4) We need a smaller, less-intrusive government.


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Invisibleorechron
LIVEWRONG
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Registered: 05/21/05
Posts: 299
Loc: Fallout Zone
Re: Evidence For The Scientific Validity Of The Concept Of Race [Re: Diploid]
    #4312592 - 06/19/05 01:44 AM (11 years, 5 months ago)

I'd be interested to know more about their sample population.


--------------------
Live by the foma that make you brave, and kind, and healthy, and happy.


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InvisibleSwami
Eggshell Walker

Registered: 01/19/00
Posts: 15,413
Loc: In the hen house
Re: Evidence For The Scientific Validity Of The Concept Of Race [Re: Diploid]
    #4312625 - 06/19/05 01:58 AM (11 years, 5 months ago)

The maker, NitroMed of Lexington, Mass., then decided on a trial using blacks only, a population that has more than twice the rate of heart failure as whites.

Is before or after adjusting for fried pork rinds consumption?


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The proof is in the pudding.


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Invisibleredgreenvines
irregular verb
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Re: Evidence For The Scientific Validity Of The Concept Of Race [Re: Swami]
    #4313239 - 06/19/05 08:45 AM (11 years, 5 months ago)

apparently less than 0.1% of our genome is different between any two persons on the planet.

the genetic diversity that we call race is less than 0.01% of the entire genetic makeup.

in that 0.01% are also some factors that relate to illnesses associated with the common genetic expressions of sub groups, some of which are hereditary and co-incide with racial distinction.

Medical testing of groups with afflictions will become more common and will probably need to become more sensitive to laypersons mis-interpretations of the meaning (usually related to teams in a game of supremacy - not about medical treatment of afflictions).

the wrong interpretation is that races are really teams competing for supremacy in a very serious version of soccer, (winner takes all).

very many people who can do math and speak languages actually believe in such an absurd game of supremacy, and will abuse results and proceedures of medical research to try and gain points in their imaginary field of play.


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Offlinegnrm23
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Registered: 08/30/99
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Re: Evidence For The Scientific Validity Of The Concept Of Race [Re: redgreenvines]
    #4313341 - 06/19/05 11:07 AM (11 years, 5 months ago)

interesting factoid:
the most genetically diverse "ethnic group" of humans is the bush people of the kalahari...

this has led some to speculate that they are the "seed people", true ancestor stock to all who left mother africa those 10s of thousands of years ago...
the pale people of europe, the yellow people of asia & their red kin in the americas, the abo folk of austral lands, the ocean/island folk of pacifica...
all human, all african, okay? all earth folk, one species, Homo sapiens sapiens, we are here, hello brothers and sisters, greeting, let us live in peace together...


--------------------
old enough to know better
not old enough to care


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OfflineTwirling
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Male

Registered: 02/03/03
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Re: Evidence For The Scientific Validity Of The Concept Of Race [Re: redgreenvines]
    #4313347 - 06/19/05 11:12 AM (11 years, 5 months ago)

Very well said.


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InvisibletrendalM
point of inflection
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Registered: 04/17/01
Posts: 19,378
Loc: Ontario, Canada
Re: Evidence For The Scientific Validity Of The Concept Of Race [Re: Diploid]
    #4313570 - 06/19/05 01:34 PM (11 years, 5 months ago)

I would prefer to use the term "demographic" here, instead of "race". There's a few reasons.

The word "race" obviously has a negative history behind it, and as such is quite likely to produce negative responses. As well, this particular subject does not refer to an entire "race" (as commonly defined) because it only refers to American blacks - obviously a specific demographic and not a "race". It is quite possible, or likely, that black Americans respond uniquely to this drug because until recently blacks in America have been segregated and repressed - which has resulted in their being a specific demographic.


--------------------
You're here because you know something.
What you know you can't explain,
But you feel it;
You've felt it your entire life.
That there's something wrong with the world.
You don't know what it is, but it's there....
Like a splinter in your mind...
Driving you mad.


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InvisibleDiploidM
Cuban

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Registered: 01/09/03
Posts: 19,274
Loc: Rabbit Hole
Re: Evidence For The Scientific Validity Of The Concept Of Race [Re: trendal]
    #4314106 - 06/19/05 05:17 PM (11 years, 5 months ago)

I would prefer to use the term "demographic" here, instead of "race". There's a few reasons.

It seems this all boils down to tying to be politically correct again. Is it not more confusing to target a medication at the so-and-so demographic than it is to target the medication at Caucasians, or Asians, or Blacks, or, Latinos, if it in fact works better in those groups? Why confuse the issue?

I've always thought, all else being equal, simple is better than complicated.

Besides, diversity is a good thing, not a bad one. Why try to downplay it. We all have our strength and weaknesses, and like it or not, we all have differences. Denying them doesn't make them go away.

Let me ask you this: Let's say it's found that the drug works best in those of us with darker-skin and not just African-Americans. What demographic label should the FDA literature use to denote this?

It is quite possible, or likely, that black Americans respond uniquely to this drug because until recently blacks in America have been segregated and repressed - which has resulted in their being a specific demographic.

Maybe. The exact cause isn't known. But even if that drug's preferential efficacy is due to historical oppression, it's still better to say it works for Blacks but not for Whites than it is to walk on eggshells and convolute the language to avoid using the word Black.

Squeamish has no place in science.


--------------------
Republican Values:

1) You can't get married to your spouse who is the same sex as you.
2) You can't have an abortion no matter how much you don't want a child.
3) You can't have a certain plant in your possession or you'll get locked up with a rapist and a murderer.

4) We need a smaller, less-intrusive government.


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InvisibletrendalM
point of inflection
Male User Gallery

Folding@home Statistics
Registered: 04/17/01
Posts: 19,378
Loc: Ontario, Canada
Re: Evidence For The Scientific Validity Of The Concept Of Race [Re: Diploid]
    #4314127 - 06/19/05 05:28 PM (11 years, 5 months ago)

Is it not more confusing to target a medication at the so-and-so demographic than it is to target the medication at Caucasians, or Asians, or Blacks, or, Latinos, if it in fact works better in those groups? Why confuse the issue?

As I already pointed out, the story isn't talking about blaks but black Americans. Unless you consider black Americans to be a race of their own, using the word "race" is confusing the issue :wink:

This isn't about being squeamish, it's about accuracy.


--------------------
You're here because you know something.
What you know you can't explain,
But you feel it;
You've felt it your entire life.
That there's something wrong with the world.
You don't know what it is, but it's there....
Like a splinter in your mind...
Driving you mad.


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Offlinezappaisgod
horrid asshole

Registered: 02/11/04
Posts: 81,741
Loc: Fractallife's gym
Last seen: 6 months, 5 days
Re: Evidence For The Scientific Validity Of The Concept Of Race [Re: trendal]
    #4314180 - 06/19/05 05:52 PM (11 years, 5 months ago)

Do any white people, American or otherwise, get sickle cell anemia? I'm not 100% sure, but I don't think so.


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Invisibleorechron
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Registered: 05/21/05
Posts: 299
Loc: Fallout Zone
Re: Evidence For The Scientific Validity Of The Concept Of Race [Re: zappaisgod]
    #4314248 - 06/19/05 06:20 PM (11 years, 5 months ago)

This argument has already been torn to shreds. Just do a search.


--------------------
Live by the foma that make you brave, and kind, and healthy, and happy.


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