freeneasy said:

deaths from specific periglandula species are rare. I am not saying you're wrong but the way you framed it is a little out of proportion. I can say you shouldn't drive on psilocybin yet I've done it and gotten there safely.

---

What... I'm sure people have driven on all kinds of substances legal and illegal and made it safely but it's always reckless and idiotic. I can't take anything you say seriously now.

freeneasy said:

deaths from specific periglandula species are rare. I am not saying you're wrong but the way you framed it is a little out of proportion. I can say you shouldn't drive on psilocybin yet I've done it and gotten there safely.

---

freeneasy said:

this should get you started:

https://petrieflom.law.harvard.edu/2022/04/13/safety-first-potential-heart-health-risks-of-microdosing/#:~:text=LSD%20and%20psilocybin%20(active%20metabolite,for%20many%20months%20to%20years.

https://www.researchgate.net/publication/377361739_Microdosing_psychedelics_and_the_risk_of_cardiac_fibrosis_and_valvulopathy_Comparison_to_known_cardiotoxins#:~:text=of%20microdosing%20over%20extended%20periods,chronic%20use%20of%20serotonergic%20psychedelics

---

Quote:

It is important to differentiate the potential risk associated with prolonged and repeated microdosing from the very limited physiological safety risk posed by a few “macrodoses” given weeks or months apart for psychedelic-assisted therapy. That said, given the lack of clinical trial evidence showing any clear benefit for microdosing, and the concerning theoretical safety risk of VHD, it is worth proceeding with caution and, at the very least, taking some weeks off between 4-week microdosing intervals. I would also encourage long-term microdosing researchers and microdosing survey app developers to begin collecting routine echocardiography results to systematically evaluate the risk of VHD.

---

MethodicalMystical said:

freeneasy said:

this should get you started:

https://petrieflom.law.harvard.edu/2022/04/13/safety-first-potential-heart-health-risks-of-microdosing/#:~:text=LSD%20and%20psilocybin%20(active%20metabolite,for%20many%20months%20to%20years.

https://www.researchgate.net/publication/377361739_Microdosing_psychedelics_and_the_risk_of_cardiac_fibrosis_and_valvulopathy_Comparison_to_known_cardiotoxins#:~:text=of%20microdosing%20over%20extended%20periods,chronic%20use%20of%20serotonergic%20psychedelics

---

You probably should have read the conclusion at the bottom of that researchgate link before making blanket statements like you have been.

Quote:

It is important to differentiate the potential risk associated with prolonged and repeated microdosing from the very limited physiological safety risk posed by a few “macrodoses” given weeks or months apart for psychedelic-assisted therapy. That said, given the lack of clinical trial evidence showing any clear benefit for microdosing, and the concerning theoretical safety risk of VHD, it is worth proceeding with caution and, at the very least, taking some weeks off between 4-week microdosing intervals. I would also encourage long-term microdosing researchers and microdosing survey app developers to begin collecting routine echocardiography results to systematically evaluate the risk of VHD.

---

The study is specifically talking about microdosing, because the concern is from longterm constant stimulation of the 5HT2 receptors. This automatically makes the occasional macrodose much less of a concern, and anyone who's done adequate research on microdosing will tell you to take breaks between dosing periods. Please put down the strawman before coming back to this topic.

Edit: Treefrog sums it up pretty well here

---

Turvenuija said:

Right, thanks. I assume I want it in dry form and not liquid?

---

freeneasy said:

Thanks for that link but he has no long term studies proving that claim.

---

MethodicalMystical said:

freeneasy said:

Thanks for that link but he has no long term studies proving that claim.

---

They're citing the same paper that you posted, even linking to it at the bottom. Again, take a step back and have a breather before continuing this conversation.

---

Nichrome said:

Can't cure dumb assness with lysergamides obviously...

---

I dunno man.  They definatley made my ass a little less dumb.

MethodicalMystical said:

Run-of-the-mill brewing malt should work fine. I got this bag off of the 'zon and everything seems to like it so far.

---

I use this brand it works fine

I bought a bunch a few years ago still working through it but I have had no issues that stems from this

ihansterx4i said:

So I made some LC and put some agar in. Went to get the mixer and realized I forgot the stir bar. What’s the move here? Just hand swirl it? Can I put it in my SAB and iso a swirl bar in it and drop it in? I don’t know what to do here.

---

Just hand swirl