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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: koods]
    #27520383 -

Hospitalization rates have some variables that are hard to adjust for. You are more likely to be hospitalized for less serious cases when there aren’t a lot of covid patients in the hospital and you may be kept longer if when there isn’t a crush of more seriously ill patients waiting for your bed


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NotSheekle said
“if I believed she was 16 I would become unattracted to her”

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: Tripsurfer]
    #27520389 -

Tripsurfer said:
No way man. VRT is a respectable MSM organization.

How is my graph wrong? It shows unvaccinated people 18-65 years old are 10 times more likely to require hospitalisation.
For 65+ year olds its less but still around 3 times more likely. Perhaps the data is skewed because they dont take partial vaccinated people into account :shrug:


And Belgium is already offering booster shoots to 65+ year olds



Im with you on this one Koods. Vaccination is effective

Still not getting the shot though


For some reason i read the dark blue as vaccinated.

Aquired immunity in general is worse as you get older. I just recently learned that your supply of T cells is not unlimited and you can run out of unassigned T cells that can be programmed to recognize a new antigen. When this happens you lose the ability to acquire immunity to any new infection you hadn’t been exposed to before.


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NotSheekle said
“if I believed she was 16 I would become unattracted to her”

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: koods] * 1
    #27520390 -

I’ve been taking an online virology course


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NotSheekle said
“if I believed she was 16 I would become unattracted to her”

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: koods]
    #27520401 -

The line at Walgreens for the moderna booster is two hours long. I’m gonna try to make an appointment for tomorrow

Welp. They’re booked up for two weeks 🤦‍♂️


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NotSheekle said
“if I believed she was 16 I would become unattracted to her”

Edited by koods (10/27/21 06:23 PM)

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: koods]
    #27520419 -

koods said:
I’ve been taking an online virology course


watching youtube videos doesn't count.

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: koods]
    #27520427 -

koods said:
I’m going to ask them to aspirate and get the shot in the right arm to reduce the chances of any untoward effects



I'll be amused if they do it. The general guidelines advise against aspiration so people don't experience unnecessary pain and turn into giant crybabies that refuse injections. It would be nice to know the dose is going to the correct place though. I wish we could just pick up the shot and self administer it.

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: Mr.GuessWork]
    #27520453 -

I can schedule a Pfizer booster this weekend but moderna isn’t available anywhere in my area until the end of next week

I gotta schedule this now because once the kids are approved it’s going to get super hard to get an appointment anywhere

I’d rather not get the Pfizer because the data is pretty clear the moderna is a superior shot


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NotSheekle said
“if I believed she was 16 I would become unattracted to her”

Edited by koods (10/27/21 06:48 PM)

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: koods]
    #27520458 -

I am going to get a booster, my doctor said to get one.
Does that count? I think is says on the CDC website to discuss stuff
with your doctor.

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: Crazy_Horse]
    #27520464 -

I’m my own doctor

My friend managed to get me an appointment tomorrow in DC. Hopefully they’ll let me get it even though im not a dc resident. He snuck in a flu vaccine too

Thanks to fiery for reminding me about the boosters and to sheekle who has full blown covid right now despite getting the apparently lame ass J&J, which reminded me how I hate being sick

Edited by koods (10/27/21 07:36 PM)

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: koods]
    #27520558 -

I made reservations for tomorrow.

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: Crazy_Horse]
    #27520600 -

Pretty sure I have bronchitis.


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"Blow up your TV, throw away your paper.  Go to the country, build you a home."

- John Prine

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: Crazy_Horse] * 1
    #27520608 -

sars-cov-2 crossed into the endemic phase in India. I haven't bothered to look but the US was pretty close as well and probably is already in it. That means it's here for good, like a seasonal flu. You can booster yourself all you want but if you are immune compromised you are always susceptible to infection. That goes for any viral infection.

Getting the flu shot doesn't give you a super shield for life from the flu. In some cases you get the flu even with a flu shot.

also the gold standard for infection testing is and always will be PCR. The reason some people are covid positive then randomly negative a day later is a false positive from an antibody test. Antibody test are not as sensitive. The most common PCR used for sars-cov-2 testing is the JANUS G3 PCR.

there's plenty of information online about how sars-cov-2 has different rates of infection based on ethnicity/genetics. It's been hypothesized and is becoming pretty concrete that it has to do with different rates of metabolism. From metabolism from a cellular level down to the organ level. The healthier your immune system (metabolism) the better chances of survival. One of the biggest problems during sickness is the inability to retain nourishment. While sars-cov-2 is milking your body of essentials you are unable to adequately resupply them.

Genetically we have different cytochromes in our liver. This is from evolution, different diets lead to different rate of metabolism. One example for instance is Native American's diet. It is so specific that being on the western diet has made them have ~50% more chance of getting type 2 diabetes.


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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: Gorlax]
    #27520652 -

Quote:
also the gold standard for infection testing is and always will be PCR


I agree. The only problem with pcr is it cannot tell the difference between infectious viral particles and degenerate viral material and it cannot tell if the viral genetic material is from an infectious source inside a body or is from a source outside the body. This usually isn’t a problem. If you’re detecting HIV in blood there’s really only one way it can be there and that is because you’re infected.

The problem with covid is they are testing in an area where your body literally does a majority of its filtering of foreign particulate matter - the nose. If you are in an environment where there are infected people shedding virus and degenerate viral material, that stuff ends up getting concentrated right where they are taking a sample. In normal situations and with fleeting exposures it’s unlikely you would have enough of this viral material to test positive, but if you are in direct contact with someone with active infection who is shedding virus and viral material, you could get quite a lot of it in your nasopharynx and test positive. In that situation, these tests may have quite a high rate of false positives if the person is not symptomatic, especially if they have been vaccinated or infected previously. If they are symptomatic and test positive it’s pretty much guaranteed it’s accurate.

A positive antibody test is very reliable proof of previous infection in someone who has not been vaccinated, or if they use a test that looks for antibodies only present after an actual infection. Antibody tests have a higher rate of false negatives because it takes a bit of time for antibody levels to rise above the detection threshold and in some cases you may not make enough to be detected with a commercially available test. You’d have to use an Elisa type screening to get highly accurate results.


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NotSheekle said
“if I believed she was 16 I would become unattracted to her”

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: koods]
    #27520664 -

As for your theory about liver enzymes, cyp2d6 and other similar enzymes metabolize certain compounds into simpler and more water soluble compounds that can be excreted by the kidneys. They have very little to do with the more colloquially used form of metabolism, which you are referring to. When they are talking about quick and slow metabolizers on that chart they are literally talking about the half life of drugs and other biologically active substances. It’s describing the speed at which a lipid soluble compound is broken down and excreted from the body.

Quote:
sars-cov-2 crossed into the endemic phase in India. I haven't bothered to look but the US was pretty close as well and probably is already in it. That means it's here for good, like a seasonal flu. You can booster yourself all you want but if you are immune compromised you are always susceptible to infection. That goes for any viral infection.



People who are immune compromised definitely get better results with more vaccine exposures. This is true with practically every vaccine on the market. Probably half the vaccines on the market require 2 to 4 doses depending on age and comorbidities. There’s nothing shocking about this and regular boosters for people who are high risk for serious illness should protect a vast majority of people who are immunocompromised. For regular people we can probably stop worrying about getting covid vaccine boosters once everyone has had their shot or been infected. Right now we are waiting for the unvaccinated to either get their shot or get infected. We could be done with this virus in a month if everyone would just fucking grow up and do their part.


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NotSheekle said
“if I believed she was 16 I would become unattracted to her”

Edited by koods (10/27/21 10:15 PM)

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: koods]
    #27520713 -

koods said:
Yeah. I’ll just say I visit someone in a nursing home often if they ask. They don’t ask though. The only
Thing they might look at is that my last dose was six months ago and that was exactly six months ago tomorrow

I’m going to a show in two weeks at a massive club. Vax only but nobody will be wearing masks so it will be nice to be at peak immunity for that.




Yeah, totally .


They didn't ask me either they were just like Yep OK.

Although they made me wait 15 minutes and before I'm pretty sure it was only 10.


I don't know about a large event without masks though... seems like taking a risk, even at peak immunity.



Like, there's probably still a 5% chance to catch it( the delta) ? I mean no one really knows.

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: koods]
    #27520741 -

koods said:
Nearly every dog in this country has been surgically altered after all.


Are we talking spaying/neutering here?

Cause it's very far from 'nearly every'...


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Let it be seen that you are nothing. And in knowing that you are nothing... there is nothing to lose, there is nothing to gain. What can happen to you? Something can happen to the body, but it will either heal or it won't. What's the big deal? Let life knock you to bits. Let life take you apart. Let life destroy you. It will only destroy what you are not.
--Jac O'keeffe

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: Jokeshopbeard]
    #27520790 -

Maybe 80%? Idk that’s not really that important to my point.


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NotSheekle said
“if I believed she was 16 I would become unattracted to her”

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: koods]
    #27520793 -

I know, it was a completely off topic post, TBF. I suspect when it comes to 'city' dogs you're right, but there's so much damn 'country' here, and dogs aint the same out there...

I haven't checked in on this COVID thread for months cause I'm really fucking bored of the stupidity surrounding it, and that was the only thing that caught my attention.


--------------------
Let it be seen that you are nothing. And in knowing that you are nothing... there is nothing to lose, there is nothing to gain. What can happen to you? Something can happen to the body, but it will either heal or it won't. What's the big deal? Let life knock you to bits. Let life take you apart. Let life destroy you. It will only destroy what you are not.
--Jac O'keeffe

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: Jokeshopbeard] * 1
    #27520965 -

That big ivermectin meta analysis published this summer that reported strong benefits for ivermectin in preventing and treating covid has been redone, this time without any of the data they used originally that has been determined to be fraudulent or of low quality. Not surprisingly, ivermectin loses all of its purported efficacy.

The authors deserve a lot of credit for going back and fixing their work.

https://www.researchsquare.com/article/rs-1003006/v1

Quote:
The results suggest that the significant effect of ivermectin on survival was dependent on largely poor quality and potentially fraudulent studies.



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NotSheekle said
“if I believed she was 16 I would become unattracted to her”

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Re: COVID-19 = SARS-CoV-2 - Novel Coronavirus Pandemic Main Thread - PART 3 (Third Wave 2021-2022 season) [Re: koods]
    #27521150 -

Thank you for posting that. It'll be a good talking point for people who get outraged by not being able to get ivermectin when they get covid. lots of the time they pick up garbage ideas from media, and it'll help to be able to walk them through the science and explain how that idea changed as we learned more about what was going on.

Also, one of the hidden plus sides of living in the south is that there is plenty of vaccine to go around for those who want it. I'll be going to get my moderna booster now. y'all have fun.

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