amilibertine said:

Have fun eating that nutmeg.  I mean, it's only been used as a torture device by prison guards.


Whatever floats you boat man.

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Quote:

Several intoxications have been reported after an ingestion of approximately 5 g of nutmeg...No information is available, however, concerning the quantitative importance of the different metabolic pathways. The acute toxicity of myristicin appears to be low. No toxic effects were observed in rats administered myristicin perorally at a dose of 10 mg/kg b.w., while 6–7 mg/kg b.w. may be enough to cause psychopharmacological effects in man ... Based on available data, it seems unlikely that the intake of myristicin from essential oils and spices in food, estimated to a few mg per person and day in this report, would cause adverse effects in humans. It is, however, at present not possible to make a complete risk assessment, as studies regarding genotoxicity and chronic toxicity, including reproductive toxicity and carcinogenicity, are still lacking.

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Quote:

The excretion of 14-C-labeled myristicin has been studied
in rats and mice [Casida et al., 1966; Kamienski and
Casida,1970; Peele, 1976]. In both species the excretion was
rapid, as it was nearly completed within 48 hours ... In rats, very little retention of myristicin was observed in the tissues, after 48 hours [Peele, 1976]. Of
the radioactivity remaining in the tissues half of the activity
was localized in the liver [Peele, 1976]. No information is
available regarding kinetics or metabolism of myristicin in
humans

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Quote:

Subacute/subchronic toxicity
Twelve white rats (strain not mentioned) were administered
10 mg/kg b.w. of myristicin daily in the food for 26
days. There were no differences in body weights between the
animals receiving myristicin and a control goup. Histological
studies of livers/kidneys showed no abnormalities that
could be attributed to myristicin.

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Quote:

One of the earliest cases of nutmeg poisoning
was recorded by de Lobel in 1576.1 In 1832 Purkinje
2 dramatically illustrated the toxic effect of this
kernel by consuming three nutmegs, producing a
narcosis which progressed to stupor. In 1903 Wallace,
3 in a review of cases of nutmeg poisoning, reported
25 from the world literature. Although one
of the patients concerned died,4 the remaining 24
recovered promptly without residual effects ... only limited observation of
nutmeg poisoning is available.

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Quote:

On the basis of the experimental work on cats
by Wallace, Dale, and Jurss it appeared that fatty
degeneration of the liver was the end-result of toxic
doses of the volatile oil or its derivative myristicin.
However, in the case reported here serial studies
of hepatic function as well as biopsy of tissue from
the liver revealed no evidence of damage to that
structure.

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Quote:

The toxic factor of nutmeg is known to be myristicin,
a constituent of the volatile oil of nutmeg.
Nutmeg in doses of 5 Gm. or more produces a
marked depressive action on the central nervous
system, as well as a less prominent stimulating effect.
The clinical course may be severe, with coma,
shock, and acidosis as its main features.

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Mafeki said:

can you get high by eating the nutmeg used for cooking or does it have to be raw?

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mpd said:

Man, you got to be pretty desperate for a buzz to go with nutmeg, don't you?

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mapleleafmarijuana said:

Mafeki said:

can you get high by eating the nutmeg used for cooking or does it have to be raw?

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Either or. The stuff I used was ground up and over 10 years old

.

mpd said:

Man, you got to be pretty desperate for a buzz to go with nutmeg, don't you?

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How so? I had a enjoyable 5 hour high that was free from a spice that wouldve been thrown out because no one used it. Do you also consider dxm a desperate high? I'm a curious guy,  I wanted to see if I could or not. I could

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Shroomslip said:

A lot of people do, yes.. Me included.

For what it's worth, I'm kinda curious (and I'm 27, growing my own mushrooms and have access to plenty of other 'real drugs'). I mean I'd heard about it before, but I found out as a kid that all those 'legal highs' never really work, so I just assumed nutmeg (and salvia) would be no different. I later obtained salvia and found out it was far from fake... So I have to wonder about this, too.

I kinda doubt I'd get around to trying it.. My body isn't as resilient as it was when I was younger, so I'm not as cavalier about what I try.

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Shroomslip said:

I was saying that even though I have plenty of other stuff available I'm still curious, meaning I don't really look at this as a 'desperate high'.

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