Quote: I don't see how there's any way we are 'experiencing raw reality' on DMT etc. No matter how hard chemicals tweak the way the brain works, the model of reality we hold in our mind is still based on our senses and perception mechanisms built for survival.
Very true. As I said towards the end of my post, I don't believe that simply taking a substance can turn back the clock of evolution, giving us an experience devoid of the perceptions we've developed. The "raw data" would be an attempt to experience the nature of existence, still with only our senses, but unbound by much of the surface-level filtering the brain takes part in. I see the brain as just another evolutionary representation, not 'real' in a sense but representative of some process that is at work.
Quote: As far as I can tell what reality is it's a sort of source code and perception of reality depends on perceptual requests: cones in our eyes sensitive to specific wavelengths etc narrow down what we need to see. We derive meaning from that and ultimately a narrative. Even if there was any way to transmit the pure source code information it would not be meaningful and I suppose it would be like 'whiting out'.
Certainly possible, but it's hard for me to believe that everything is code yet eyeballs, rods and cones are somehow separate from that code, and are 'real' physical objects, that serve as mechanical detectors, that trigger simple sparks of energy in which exists key ingredients of conscious existence. I'd be much more inclined to believe that none of it exists at all, and is again a representation formed by evolution(possibly a multi-dimensional force) to explain this illusion of reality we experience. In that case, the code itself is an illusion as well. If any of this is true, I have no idea how deep the human mind is even able to go in recognition.
Quote: I don't even think that happens, I think when we have a sort of white out or other mystical states of consciousness involving non-duality and the like, we still experience our mental state but we may gradually lose differentiation. fMRI of people on acid reveals that it causes a sort harmonization of brain faculties, a sort of melding which explains the aforementioned synaesthesia and - what I believe: - not yet well understood forms of synaesthesia which are at the moment only explained by phenomena like 'auras' and even phenomena which work like synaesthesia but involve cross-chatter of cognitive faculties rather than sensory stimuli.
What exactly is our mental state, though? With meditation, it is possible for even beginners to reach states devoid of any sense of their "self"... it doesn't much matter what your past sensory experience is, or even if you're deaf, blind, etc. Experienced practitioners can reach the point where at the neurological level they basically eliminate the startle response and are unresponsive to incoming perceptual stimulation. A shaman from the Amazon and an american oil CEO can take ayahuasca and have hauntingly similar experiences. Yes, it's all surface-level and tied to what we're able to perceive, but I don't believe that makes it any more explainable. There may be a sense of self that continues to exist beyond the senses we know here, there may be a way of tuning into some 'other', we just don't know.
Quote: I agree accounts of telepathy between fellow trippers is not yet explained but I think it eventually will be in ways which agree with both science and the phenomena without degrading the experiences.
You're much more optimistic than I am 
Quote: In a way I do agree that DMT and similar drugs lift the veil of reality but not in the way you seem to be talking about ^ . I think it reveals our mental model of reality and the inner workings of our sensory faculties and how we try to make sense of it with a stream of consciousness and narrative. However our model of reality is hardly accurate because we only see such a limited part of the spectrum.
Very good point. I don't think we're too far off in what we're saying. I'm not arguing that my theories are correct, only that the science can be applied in ways that make them interesting to ponder.
Quote: If we are able to see a sort of source code it will not be that of actual reality but of our personal mental models of reality. Most people are not aware that this distinction exists.
I feel the same way, but it could be that "actual reality" is something we are intimately familiar with already, and in this realm the only way of experiencing it is through sensory representation, in which DMT/psilocybin can give us as accurate of a picture as we're able to perceive and bring back.
Quote: At best we may experience such things because psychedelics tend to have effects on our sense of novelty which can cause us to experience things as if it is our first time.
Quite often I actually have the opposite effect. I experience realms that seem like places I have a history with, things that are familiar.
Quote: Nichols argues this involves the locus coeruleus. Effects of psychedelics may also cause us to divert from trodden paths and consolidated neural pathways but more free activity. Without as much constraint we are much freeer to see beyond routine vision and without hiding things like our nose.
I always attributed the LC activation by LSD/mescaline to simply account for the stimulant type effects, I never really dug deeper. It'd be interesting to see what else that it could suggest, especially since it appears a similar process takes place with DMT/psilocybin.
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