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Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects
    #24028132 -

The common prescription drugs Neurontin and Lyrica are implicated in a study as "causing brain decline faster than any drug known to mankind" and potentially also have adverse effects on foetal development.

Article


Discuss intelligently


--------------------
Omnicyclion.org
personal empowerment for the world

:nyan: LGBT - Love God Before Tradition :nyan:

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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: Asante] * 3
    #24028137 -

When I view the article, there is a little "1" which I'd assume is a source, though I don't see a source listed.

In the absence of proof or data, I'd assume this is bunk. These drugs have been marketed long enough that if there were some catastrophic side effect we'd know about it by now.


--------------------
...the whole experience is (and is as) a profound piece of knowledge.  It is an indellible experience; it is forever known.  I have known myself in a way I doubt I would have ever occurred except as it did.

Smith, P.  Bull. Menninger Clinic (1959) 23:20-27; p. 27.

...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.

Osmond, H.  Annals, NY Acad Science (1957) 66:418-434; p.436

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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: Asante] * 3
    #24028139 -

Looks like clickbait targetted at users of Lyrica, aimed at getting them to purchase supplements from the "source" of the article, http://www.wellnessresources.com/, instead.


But I don't know anything about Lyrica. I wouldn't use this article as any substantial proof of anything given it's source material clearly stated on the bottom of the article and sloppy execution of it's information.

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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: PatrickKn]
    #24028144 -

I'd think all gaba drugs could cause brain damage if abused enough for long enough. :shrug:


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          :dancingbear: Free time is the only time :dancingbear:                    :thatsinteresting:

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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: Asante]
    #24028146 -

Asante said:
The common prescription drugs Neurontin and Lyrica are implicated in a study as "causing brain decline faster than any drug known to mankind"

Discuss intelligently



lies... marijuana has been known to do this in as little as 2 marijuana cigarettes






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California Has Legalized Child Prostitution

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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: Asante]
    #24028150 -

I was put on Gabapentin and later Pregabalin to treat the paresthesia in my feet.
They did nothing for the condition and I didn't like the side effects of either.
They both gave me wild mood swings and a terrible, unquenchable thirst.

I told my doctor I'd rather deal with the pain and if it got to bad I'd self medicate with Cannabis, which works! I only need the slightest of tokes, no tolerance, and I feel better for hours.

I've heard that they are abused in prisons for the high :eek:.


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whether low pressure sucks or high pressure blows...
it's a bugger to cycle in.

even though I'm feeling good
Something tells me I'd better activate my prayer capsule

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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: deucedbi9] * 1
    #24028155 -

Stanford Medical link


--------------------
Omnicyclion.org
personal empowerment for the world

:nyan: LGBT - Love God Before Tradition :nyan:

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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: Asante] * 2
    #24028184 -

Lyrica is now approved for at least 5 indications.

Across the clinical trials required for these approvals exist data for thousands of patients probably number in the tens of thousands of thousands of "patient years." There don't appear to be reports of "serious brain deterioration."

Most place greater weight on the human, clinical data than data "based on experiments in cell culture and in mice."


--------------------
...the whole experience is (and is as) a profound piece of knowledge.  It is an indellible experience; it is forever known.  I have known myself in a way I doubt I would have ever occurred except as it did.

Smith, P.  Bull. Menninger Clinic (1959) 23:20-27; p. 27.

...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.

Osmond, H.  Annals, NY Acad Science (1957) 66:418-434; p.436

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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: badchad]
    #24028216 -

I remember seeing commercials for lyrica and being shocked at all the side effects...


--------------------
Don't worry about me, I've got all that I need. And I'm singing my song to the sky

You know how it feels, With the breeze of the sun in your eyes. Not minding that time's passing by

I've got all and more, My smile, just as before. Is all that I carry with me

I talk to myself, I need nobody else. I'm lost and I'm mine, yes I'm free


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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: musiclover420]
    #24028247 -

I don't trust any drugs that haven't been used for at least over a hundred years. Other than some of the good stuff like acid and molly. I'll take mostly anything if its free though. I just won't trust it.

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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: cannabinated]
    #24028256 -

cannabinated said:
I don't trust any drugs that haven't been used for at least over a hundred years.


Antibiotics.

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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: PatrickKn]
    #24028281 -

PatrickKn said:
cannabinated said:
I don't trust any drugs that haven't been used for at least over a hundred years.


Antibiotics.


There are many natural antibiotics that have been used for thousands of years I imagine.

Many traditional plant medicines have antibacterial and parasitic effects.

Not to mention modern antibiotics have their downsides too such as being indiscriminate and killing many beneficial organisms in the body that can take a while to replenish.


--------------------
Don't worry about me, I've got all that I need. And I'm singing my song to the sky

You know how it feels, With the breeze of the sun in your eyes. Not minding that time's passing by

I've got all and more, My smile, just as before. Is all that I carry with me

I talk to myself, I need nobody else. I'm lost and I'm mine, yes I'm free


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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: PatrickKn]
    #24028283 -

There's still no link to the *actual journal article* in this thread.. Even the Stanford 'news' link Asante posted lacks one.

But I used to be prescribed 1.2g of gabapentin per day. So it's concerning to me.

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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: PatrickKn] * 5
    #24028284 -

If cannibinated gets a compound fracture, he's gonna take some whiskey & laudanum, then ask his barber to saw his leg off.

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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: musiclover420]
    #24028289 -

musiclover420 said:
Not to mention modern antibiotics have their downsides too such as being indiscriminate and killing many beneficial organisms in the body that can take a while to replenish.


Good points. I hadn't considered the idea that enough decades haven't passed to see the real downsides of antibiotics in the long term when I made the post either. Downsides aside, they have increased mortality quite a bit and it would be needless to not trust them if you have a bad infection.

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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: PatrickKn] * 2
    #24028304 -

PatrickKn said:
musiclover420 said:
Not to mention modern antibiotics have their downsides too such as being indiscriminate and killing many beneficial organisms in the body that can take a while to replenish.


Good points. I hadn't considered the idea that enough decades haven't passed to see the real downsides of antibiotics in the long term when I made the post either. Downsides aside, they have increased mortality quite a bit and it would be needless to not trust them if you have a bad infection.


*decreased* mortality!

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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: PatrickKn]
    #24028328 -

PatrickKn said:
musiclover420 said:
Not to mention modern antibiotics have their downsides too such as being indiscriminate and killing many beneficial organisms in the body that can take a while to replenish.


Good points. I hadn't considered the idea that enough decades haven't passed to see the real downsides of antibiotics in the long term when I made the post either. Downsides aside, they have increased mortality quite a bit and it would be needless to not trust them if you have a bad infection.


I have nothing against antibiotics, I have taken em at least a few times for various purposes. Last time it was after a minor surgery to prevent an infection I think.

But exactly, there is no way of knowing all the long term effects they could have.

One scenario that comes to mind is pregnant women. It would make sense a mother would pass bacteria onto her babies before giving birth. So if a pregnant woman had been taking antibiotics and not balancing it with pro biotic supplements she could give birth to a baby lacking many beneficial organisms that could lead to various complications.

Who knows if that is how it works but it would make sense to me and seems like a possible issue with antibiotics.

Of course if I ever had a serious infection I would take some in a heart beat :shrug: I take probiotics pretty regularly though.


--------------------
Don't worry about me, I've got all that I need. And I'm singing my song to the sky

You know how it feels, With the breeze of the sun in your eyes. Not minding that time's passing by

I've got all and more, My smile, just as before. Is all that I carry with me

I talk to myself, I need nobody else. I'm lost and I'm mine, yes I'm free


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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: eeso]
    #24028334 -

eeso said:
PatrickKn said:
musiclover420 said:
Not to mention modern antibiotics have their downsides too such as being indiscriminate and killing many beneficial organisms in the body that can take a while to replenish.


Good points. I hadn't considered the idea that enough decades haven't passed to see the real downsides of antibiotics in the long term when I made the post either. Downsides aside, they have increased mortality quite a bit and it would be needless to not trust them if you have a bad infection.


*decreased* mortality!


*

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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: PatrickKn]
    #24028401 -

PatrickKn said:
cannabinated said:
I don't trust any drugs that haven't been used for at least over a hundred years.


Antibiotics.


Antibiotics are almost done with soon there's going to be a lot of dead mofo's

And yeah maybe 50 years but all I'm saying is even some of the drugs I love the most haven't been tested enough.

Also alcohol is bad for u

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Re: Gabapentin and Pregabalin may cause serious brain deterioration, also possibly birth defects [Re: Burke Dennings]
    #24028410 -

Burke Dennings said:
If cannibinated gets a compound fracture, he's gonna take some whiskey & laudanum, then ask his barber to saw his leg off.


I would OD and die. Laudanum sounds kinda awesome though, like natural lean.

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