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Welcome evermore to gods and men is the self-helping man. For him all doors are flung wide: him all tongues greet, all honors crown, all eyes follow with desire. Our love goes out to him and embraces him, because he did not need it.
I think he means how long will it take for the shoes to become worn in and not hurt your feet/ankles. I heard it's better for your feet to run bare foot, but it is rather impractical. As for the question, no idea. Maybe wear them around the house or wherever before you run in them, to make sure your feet are used to them.