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Mushrooms, Mycology and Psychedelics > The Psychedelic Experience
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InvisibleAhab McBathsalts
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mescaline / hippyfliping cross tolerance
    #3776952 - 02/14/05 12:25 AM (19 years, 2 months ago)

How much cross tolerance can I expect to affect a mescaline trip if i've hippyflipped 4 or 5 days earlier?

*edited for clarity.


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Edited by evilnick (02/14/05 04:32 AM)

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OfflineSilent_Echo
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Re: mescaline / hippyfliping cross tolerance [Re: Ahab McBathsalts]
    #3777581 - 02/14/05 07:10 AM (19 years, 2 months ago)

Hippieflipping is MDMA/Mushrooms right? and just to clear it up, what is candyflipping? acid/mdma? i dont think your tolerance will be that high, just account for it and take alittle extra just to be sure...wish i could get some mesc. id be nice :-)

Peace,
Alex :mushroom2:


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Life is only a dream and we are the imagination of ourselves.
-Bill Hicks (R.I.P)

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OfflineNutmeg
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Re: mescaline / hippyfliping cross tolerance [Re: Silent_Echo]
    #3777911 - 02/14/05 09:27 AM (19 years, 2 months ago)

There's already going to be cross tolerance for the mushrooms and even more cross tolerance for the MDMA to be accounted. 5 days..... I'm pretty sure you wont have any problems anyways. Ive tripped back to back on several occasions that's when you have to worry about tolerance :mushroom2:

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Offlinerdnp2035
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Re: mescaline / hippyfliping cross tolerance [Re: Nutmeg]
    #3777940 - 02/14/05 09:36 AM (19 years, 2 months ago)

There's probably a bit of tolerance going on for 10 days or so..altough most of it will be gone in about 3-4. Considering its Mesc, however, if it were me I would hold off a little longer to max out the readyness.

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Offlinedudeownsproperty
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Re: mescaline / hippyfliping cross tolerance [Re: rdnp2035]
    #3825841 - 02/24/05 12:38 AM (19 years, 1 month ago)

there is only cross-tolerance between tryptamines (psilocybin/LSD/etc) right? between phenethylamines (MDMA/mescaline) there shouldn't be any, and especially not between the mushrooms and the mescaline..

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OfflineBal0n
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Re: mescaline / hippyfliping cross tolerance [Re: dudeownsproperty]
    #3826283 - 02/24/05 05:51 AM (19 years, 1 month ago)

What made you think LSD is a tryptamine?


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"A human being is part of a whole, called by us the 'Universe' - a part limited in time and space. He experiences himself, his thoughts and feelings, as something seperated from the rest - a kind of optical delusion of his consciousness. This delusion is a kind of prison for us, restricting us to our personal desires and to affection for a few persons nearest us. Our task must be to free ourselves from this prison by widening our circles of compassion to embrace all living creatures and the whole of nature in its beauty."
- Albert Einstein

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Offlinealsey
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Re: mescaline / hippyfliping cross tolerance [Re: Bal0n]
    #3826325 - 02/24/05 06:22 AM (19 years, 1 month ago)

LSD is a tryptamine based molecule.

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OfflinePsiloman
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Re: mescaline / hippyfliping cross tolerance [Re: dudeownsproperty]
    #3826342 - 02/24/05 06:36 AM (19 years, 1 month ago)

Quote:

dudeownsproperty said:
there is only cross-tolerance between tryptamines (psilocybin/LSD/etc) right? between phenethylamines (MDMA/mescaline) there shouldn't be any, and especially not between the mushrooms and the mescaline..



Well...Do you know the biological phenomenon of tolerance? In general classic hallucinogens such as LSD,Mescaline and various tryptamines exhibit their effects being agonists at 5HT-2a receptors.When these receptors ,in laymans terms" "have had enough" they retract in the nerve cell (not permanently) hence you have tolerance because the next administered dosage will not find many receptors to bind on.

SInce psilocin and mescaline mediate their effects through the same receptor then there is tolerance between them!


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Offlinedudeownsproperty
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Re: mescaline / hippyfliping cross tolerance [Re: Psiloman]
    #3830166 - 02/24/05 09:11 PM (19 years, 1 month ago)

i had never read anything about that before, just between tryptamines. i will definitely take that into consideration in the future. thanks!

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Mushrooms, Mycology and Psychedelics > The Psychedelic Experience
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