You are just reading grower fancy. 
Substrate has a lot to do with mushroom potency. Just compare doseage levels from the 70's with their techniques and substrate to present day methods and substrate.
If you want to come up with your own strain get some petri's, agar mix, a 5-10ml pipette, some basic supplies, a clean area and time and read a few pages out of TMC on mushroom genetics and your set :-)