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Mushrooms, Mycology and Psychedelics > The Ethnobotanical Garden
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The Simple Plant Isoquinolines
    #982354 -

Ok so Alexander Shulgin book is almost out, but what is an Isoquinolines. I only have a very vague idea of it being something to do with psychedelic opiates but i may be wrong. Also any one know of any plant sorces for them.


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Re: The Simple Plant Isoquinolines [Re: EvilGir]
    #983475 -

Isoquinoline and quinoline are a heterogeneous group of alkaloids with a toxicity to humans and animals.

Argemone Mexicana is one that contains these alkaloids.

Some of the alkaloids are: papaverine, sanguinarine, protoverine, and chelidonine. They are gastrointestinal tract irritants, CNS stimulants, and vasodialators.

For example Isoquinoline alkaloids are found in Argemone Mexicana which Salvia England has been posting heavily about lately: pics of his plants and articles about poisonings. It can have effects ranging from relaxation to euphoria and even convulsions or seizures.

I'd suggest reading some of the posts by Salvia England. Especially the one containing many articles regarding its use and poisonings.

Here is a quick excerpt from a plant poisnonings article regarding some common Isoquinolines:

Cytisine is similar in action to nicotine. In any isoquinoline or quinoline ingestion, GI irritation is common, and toxic ingestions almost invariably result in emesis. Onset of symptoms is rapid. GI upset and vomiting start 45 minutes to 4 hours after ingestion. CNS effects include drowsiness, weakness, loss of coordination, muscle fasciculations, seizures, coma, and mydriasis. Some anticholinergic effects, such as urinary retention, may manifest. Respiratory failure, as in nicotine poisoning, is observed in patients with severe cases.

The toxic alkaloids are concentrated in the pealike or brightly colored seeds in laburnum, mescal bean, and lupine. Danger to humans predominantly stems from these seeds' attractive appearance to children.

Most of the isoquinolines are noxious in smell and taste and discourage ingestion, thus human toxicity is rare. Interestingly, some domestic species tolerate ingestion of isoquinoline and other alkaloids, and humans can ingest toxic alkaloids from the milk of a poisoned animal and manifest symptoms.

Celandine and bloodroot may cause dermatitis, and celandine extract has been implicated in cases of acute hepa


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Re: The Simple Plant Isoquinolines [Re: EvilGir]
    #983630 -

The book is out, and I guarantee it will bore the hell out of you. Its simply an index of molecular structures. No stories, no trip reports, no effects, no dosages... just a few hundred pages of molecular substitution charts.

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Re: The Simple Plant Isoquinolines [Re: Murple]
    #983952 -

i think the story is that he wrote this book just to catalogue and organize all the data he needed to write qihkal, which is coming out soon. don't remeber where i heard this, though... :confused: 


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Re: The Simple Plant Isoquinolines [Re: krispyfi]
    #985771 -

Oh well just thourght it could of been a new group of psychedelics. Gues i will leave that book alone and wait just for pihkal.


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Re: The Simple Plant Isoquinolines [Re: EvilGir]
    #8504855 -

Sorry to dredge this thread up but has anyone read this book yet?

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Re: The Simple Plant Isoquinolines [Re: crazyeddie]
    #8509572 -

damn i dont think that book was ever finished... it would have broadened the selection of RC's like... a lot

i just searched it up on google  and it turned up nothing since 2002

its a shame that it hasnt been published, swim would have loved to have tried novel quinoline psychedelics


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Mushrooms, Mycology and Psychedelics > The Ethnobotanical Garden
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