That ain't silly, that's top science!
AFAIK it's still unknown, but most drugs work acutely, while Psychedelics seem to cause a sort of chain reaction, like tipping the first stone of a domino rally game. If you take alot more than a decent dose the trip lasts abit longer, but not nearly as much as it's intensity increases. With DMT you get a 15-45min domino rally, Shrooms generally push 4-6 hours, LSD twice that and the absolute recordbreaker as Psychedelic duration is 2C-G-5, a freakylooking mescaline/DOM analog that lasts a whopping 32-48 hours. (I'd rather eat SHIT than take a Level 5 of that one )
It was discovered by Alexander Shulgin: Please go to Erowid's online books section and DOWNLOAD his books PiHKAL and TiHKAL: They describe synthesis, dosage and effects of ALL PSYCHEDELICS!! The mentioned 2C-G-5 can be found in the former, while our beloved shroomie molecules can be found in TiHKAL under 4-HO-DMT.
In the interaction of brain and molecule, biology and psychology lies the duration of a certain compound. Should you discover in a trip that you, for instance, are raided by the DEA this might immediately abort the psychedelic effect or, more often, you either wind up eating the wallpaper in a horrortrip or jab a flute up your ass and start playing "Star Spangled Banner" for them. 
HPPD... Brains have got a quality called "Neuroplasticity". This basically means that connections between nerves are being made and broken all the time. Something can either get anchored in your brain or escape it, making way for something else. You can aquire new skills or lose older ones. My personal guess is that your brain can learn to function psychedelically (or unlearn functioning "normally") and get rewired to this neurologically. This can prove to last or cease after some time, as neuroplasticity goes both ways.
The brain doesn't return to normal: the brain MAKES normal. People g(r)oing insane simply move into a "normal" that leads to problems within themselves or with the world around them, and this explains why the truely maddened people seldom think thy're looneytunes, as there wasn't a sudden discontinuity in their sense of "normalcy". (This is what's happened to me so I'm told)
Since I'm on a roll here, lemme adress "Drug tolerance". People tend to think: if you chronically use things like Heroin, Xanax and the like, the stuff stops working. -BUZZZ! WRONG ANSWER!!- If that were true there would not be junkies and such. If most people use Mushrooms or LSD daily they indeed stop working. And what do you do? You stop using, as simple as that.
Not so with Heroin etc. They KEEP ON WORKING. Yeah right, you think.. Hard Drugs alter the activity of some neurotransmitter systems in the brain. Now this extra boost gives the "oomph" that inspires the guys in the "Other Drugs Forum" to eat Shroomery megabytes  But when you keep on using this boost, your body starts DEPENDING on it and puts out less & less of it's own substances that cause this effect.
There are two reasons for this: The first is that your body is downright lazy and energy-conserving (an athlete struck by a flu for two weeks can no longer run his marathon the next week since it's all about "use it or lose it", as lots of excommunicated celibate priests have discovered to their dismay) and the second reason is that your body is geared to bring you to your own particular "normalcy", the sometimes dull and drug-inspiring state called homeostasis by biology dudes that want to exclude layman opinions.
So your high doesn't disappear: the smack is every bit as active as before, only you've pushed it UNDER YOUR NORMALCY EQUILIBRIUM. Should you stop taking your vitamin H you drop below this and get the exact opposite of the drug-effect you wanted to experience. THIS is withdrawal, and you'll only get out of this limbo if you wait for homeostasis to kick in again or you jump over the jail fence, scream: "Give me Librium or give me Meth" and jab a needle up your arm again. So hard drugs do not stop working like Psychedelics do. If this were the case, they would not be "physically addictive".
I love reading up on all sorts of stuff, this in fact is the reason I got hooked up to the Net in the first place! Some years ago I was still merrily snorting Smirnoff, shooting up Marijuana and smoking Mushrooms, but the loving Shroomery community set me straight as to what belongs where 
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