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Question about suboxone and opiate tolerance
    #21732901 -

So my question is if someone took 8mg suboxone 3-4 times a week on a regular basis do you think it would mess with your opiate tolerance? Also if you use opiates at least once a week but sometimes twice Like will it be harder to get a good high because of using the suboxone (and the opiates) somewhat regularly?

I've had two people tell me they don't think it would mess with tolerance but I think it does what do you guys think?


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:mushroom2::stoned::mushroom2:

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Re: Question about suboxone and opiate tolerance [Re: burningstar06]
    #21732922 -

AFAIK Suboxone and Opiates don't have a cross tolerance, so the time you spend off opiates, and On Subs should technically be a tolerance break.

I think.


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The chances of you even being born, Were forty million to one. There's two parts of the statistic And I want you to live through one
3/8/95 - 7/10/15 Rest In Paradise, Brother.
Sheekle said:
yeah, i said i was afraid of psychonautica

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Re: Question about suboxone and opiate tolerance [Re: Psychonautica]
    #21732944 -

suboxone maintenance keeps your tolerance level the same unless they taper you down.


subutex you can take and not worry about it fucking with your opiate tolerance, or getting you sick.....suboxone has 2mg/8mg of naloxone which if you take too soon after an opiate dose it sends you into precipitated w/d



suboxone will block i think its like 2/3s of your opiate receptors, so you can only get 1/3 as high on opiates while having suboxone in your system. if you take enough opiates you can chip away at that suboxone and open up the rest of your receptors and THEN you get high like normal, but until you break through the sub on your opiates youll feel a diminished effect



so if you are used to 500mg of oxycodone a day, and are given suboxone for maintenance, if you take the subs for a year or 6 months when you stop taking the suboxone you actually end up with the same w/ds you wouldve started with in the first place but they will last a month+ depending on how long youve been taking suboxone


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ModestMouse said:
"Much love for all of the regs here that's all I got to say
:goodnight: "

:heart:

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Re: Question about suboxone and opiate tolerance [Re: trippinballs420]
    #21733453 -

Subutex and suboxone act the same way in your body.  Just because tex doesn't have naloxone in it doesn't mean it won't increase your opiate tolerance.  It will increase your tolerance.  The more your use the higher your tolerance to all opiates will be.  It also takes about 3 days to get back to baseline with subs so that you can do other opiates,  but I warn you if you make subs a habit other opiates will lose their magic.  You'll still get high but it won't have that kaboooom that you usually get.


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I like lasagna.


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Re: Question about suboxone and opiate tolerance [Re: DTCharlieB]
    #21733495 -

also I've used subs 3 to 4 times a week and your gonna have to take double to triple your amount of your d.o.c to feel it.  Subs are a bitch. My advise don't start them.  They ruin real opiates and the w/d is horrible, especially if you cold turkey.


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I like lasagna.


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Re: Question about suboxone and opiate tolerance [Re: DTCharlieB] * 1
    #21733604 -

Quote:
your gonna have to take double to triple your amount of your d.o.c to feel it.




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Re: Question about suboxone and opiate tolerance [Re: teamkiller]
    #21733722 -

Disregard everything trippinballs420 said, 500mg oxycodone LMAO even the highest toleranced person would be risking taking that much.  Naloxone 2mg taken sublingualy has no effect and even injected its effect is negligible.  Therefor subutex has the same exact effect as suboxone.  They only put the naloxone in to supposedly prevent addicts from injecting their subs but people still do.  It is the Buprenorphine itself that blocks your opiate receptors keeping you from being able to get high on other opiates and sends you into withdrawl if you take it while on opiates.

To answer your question yes subs will fuck up trying to get high on other opiates.  Subs have an extremely long half-life, 36 hours I believe, so it builds up in your system over the days you take it and takes a long time to leave your system.  I have found if I take <1mg in the morning I can still get high later that day as long as I haven't been taking a ton the days before that.  Ideally you want to wait 3 days since your last suboxone dose to feel the full effect of your drug of choice.

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Re: Question about suboxone and opiate tolerance [Re: philsfan]
    #21733753 -

Suboxone is the worst drug I've ever taken. It sucks fuckin dick. Sick for 16 hours high for 24. Have fun.


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Your god is dead, and I killed him.

When you’re lost, here I am. Forever with your soul


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Re: Question about suboxone and opiate tolerance [Re: philsfan]
    #21733881 -

philsfan said:
Disregard everything trippinballs420 said, 500mg oxycodone LMAO even the highest toleranced person would be risking taking that much.  Naloxone 2mg taken sublingualy has no effect and even injected its effect is negligible.  Therefor subutex has the same exact effect as suboxone.  They only put the naloxone in to supposedly prevent addicts from injecting their subs but people still do.  It is the Buprenorphine itself that blocks your opiate receptors keeping you from being able to get high on other opiates and sends you into withdrawl if you take it while on opiates.

To answer your question yes subs will fuck up trying to get high on other opiates.  Subs have an extremely long half-life, 36 hours I believe, so it builds up in your system over the days you take it and takes a long time to leave your system.  I have found if I take <1mg in the morning I can still get high later that day as long as I haven't been taking a ton the days before that.  Ideally you want to wait 3 days since your last suboxone dose to feel the full effect of your drug of choice.


bullshit, ive done over a gram of oxycodone in a day without any bupe in my system, my daily doses were between 300mg and 1g consistently for the last 2 years i was in my addiction. i was *supposed to be* on suboxone maintenance at the highest legal dose (32mg/day) for 4.5 years i know what im talking about maybe not scientifically but i know it first hand

ive been on 32 mg and broken through the bupe hours after taking my last pill.

i was wrong about the naloxone and mistook it as naltrexone.


yes you can get high off other opiates while on suboxone, just you need to take more to break through the bupe on your receptors.

no your opiate tolerance doesnt go up on suboxone - it stays the same. if used as maintenance your suboxone habit will end up being worse as youll end up addicted to suboxone which is way worse coming off of than a short acting opiate.


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ModestMouse said:
"Much love for all of the regs here that's all I got to say
:goodnight: "

:heart:

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Re: Question about suboxone and opiate tolerance [Re: DTCharlieB]
    #21733898 -

DTCharlieB said:
also I've used subs 3 to 4 times a week and your gonna have to take double to triple your amount of your d.o.c to feel it.


that didnt happen to me at all i could have 0 w/d as long as i took like 12mg of bupe even during the height of my habit (avg 5-600mg/day)


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ModestMouse said:
"Much love for all of the regs here that's all I got to say
:goodnight: "

:heart:

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Re: Question about suboxone and opiate tolerance [Re: trippinballs420]
    #21734193 -

trippinballs420 said:
DTCharlieB said:
also I've used subs 3 to 4 times a week and your gonna have to take double to triple your amount of your d.o.c to feel it.


that didnt happen to me at all i could have 0 w/d as long as i took like 12mg of bupe even during the height of my habit (avg 5-600mg/day)


More or less what I meant was when you have bupe in your system,  and you will if you take it 3 or 4 times a week, your going to have to increase opiate dose to feel it like you normally would.

Also in most cases subs will increase opiate tolerance.  They both bind to the same receptors and those receptors will act as if they have any other opiate binding to them, thus increasing tolerance just the same as taking oxy everyday will increase tolerance.

I've read where people say they haven't experienced any tolerance increase toward opiates while using subs but they seem to be the minority in my experience.  But everyone is different so you can never know for sure until you try it yourself.  Which in case of the opiate game I suggest you not try it at all.

"You take an opiate, you piss the bed." That should be DAREs new slogan. Haha.


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I like lasagna.


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Re: Question about suboxone and opiate tolerance [Re: DTCharlieB]
    #21734278 -

ohhh yeah i gotcha, i agree. i must be in that minority because my tolerance never went up when i went on subs, it just stayed the same. and you for sure have to dose more if bupe is in your system but you can definitely still get high if you use enough


i totally agree, there needs to be special campaigns in the drug classes in schools about opiates, they are fucking up sooooooooo many people across all walks of life.


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ModestMouse said:
"Much love for all of the regs here that's all I got to say
:goodnight: "

:heart:

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Re: Question about suboxone and opiate tolerance [Re: burningstar06]
    #21734325 -

I credit switching back between suboxone and full-agonist opiates with totally ruining my tolerance.

It definitely messes with tolerance alot.  8mg is a high dose, and it really fucks with you over time if you keep switching back and forth.  I'd really not recommend it.

Of course your opiate tolerance goes up on suboxone, plus the blocking effect lasts a while.  Even if you can get high 24h after dosing suboxone, it will not be as good as if you didn't take the sub.  Basically you have to wait until you're sick to get the full effect.

Honestly if you're worried about managing your opiate tolerance, it's too late.  You're hooked.

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Re: Question about suboxone and opiate tolerance [Re: burningstar06]
    #21734499 -

I would not get a full blown rush from a shot of dope for at least 36 hours after taking subs, I could get a decent little rush 24 hours after, but always had to wait the full 36 hours to get full blown faded.


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