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Amitriptyline Subjective Effects
    #22338557 -

My psych prescribed  10-30mg of Amitriptyline for sleep, how does it compare to other sedatives? I have found no information on it other than that it may cause drowsiness, I would normally just look up other drugs in the same class and can usually get some idea but it seems like Tricyclic Antidepressants vary wildly in their effects. Can someone give me a idea of what to expect?


Here's what I've tried, so using similarities between these would be helpful. It's kinda in the order of how much I enjoyed the effects, which generally correlates in better at helping me fall asleep without a hangover.

Trazodone (12-200mg)
Diphenhydramine (50-250mg)
Alcohol (too much)
Phenibut(500-2500mg)
Opiates (usually around the equivalent of 10mg hydrocodone)
Ambien (10-30mg)
Gabapentin (300mg-6000mg)
Weed (tolerance/quality changes)


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Re: Amitriptyline Subjective Effects [Re: Urist]
    #22338598 -

Amitriptyline like trazodone causes its sedation through serotonin antagonism. Amitriptyline does not however metabolize into any serotonin agonists like trazodone, which directly work against the antagonism :thumbup: Morning drowsiness will probably be about on par with trazodone, but varies pretty greatly.


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Re: Amitriptyline Subjective Effects [Re: DustBunny]
    #22338615 -

I was on it for a bit for sleep. I would compare it to trazodone in terms of effects and over all feel. Trazodone usually brought me down a bit faster, it felt like.


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Mama, here comes Midnight, with a dead Moon in it's jaws.

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Re: Amitriptyline Subjective Effects [Re: pirate-blues]
    #22338697 -

Great... ime Trazodone just trades day time sleepiness for day time shittiness...


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Re: Amitriptyline Subjective Effects [Re: Urist]
    #22338752 -

I was prescribed amityptaline for paresthesia. I cant remember the dosage but the side effects were a raging thirst and a feeling of being hungover all the time. Though it did enable me to get back to sleep if I had to 'get up' in the night.

Gabapentin at just 100mg, gave me severe mood swings, along with the thirst.
I'd go from laughing inanely at nothing one minute, to spitting rage the next.
I even got stroppy with a security guard in a shop who'd accused me of stealing. He'd seen me putting my water bottle back in my pocket and assumed...I showed him the bottle and then told, or rather hissed at him to "now piss off", not like me at all. :nonono:

If you have the means, try downloading this onto an mp3, stick or whatever>

http://mynoise.net/NoiseMachines/thunderNoiseGenerator.php

to listen to in bed.


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whether low pressure sucks or high pressure blows...
it's a bugger to cycle in.

even though I'm feeling good
Something tells me I'd better activate my prayer capsule

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Re: Amitriptyline Subjective Effects [Re: deucedbi9]
    #22338828 -

It is the worst drug you could possibly take. It fucking blows dick. I remember taking 200mg (2 100mg tabs) and becoming a legit mental zombie. I felt like I was asleep but i wasn't. It's a terrible drug and you are better off using unisom for sleep. It also gave me insane restless leg syndrome so how anyone could sleep on it is beyond me.

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Re: Amitriptyline Subjective Effects [Re: Gorlax]
    #22338899 -

Took the minimum 10mg....and yeah, it definitely feels like benedryl/trazodone....god I hate sleeping pills...


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Re: Amitriptyline Subjective Effects [Re: Urist]
    #22338937 -

10mg? that's it. My friend and his mom were prescribed them in the 50 and 100mg range for migraine headaches. His mom killed herself so beware of those serotonin drugs.

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Re: Amitriptyline Subjective Effects [Re: Gorlax]
    #22339059 -

My psych said not to go over 30mg. The dose for sleep is a lot lower than the dose for depression. At this dose it feels very anticholinergic, kinda like 150mg of benedryl after you build a bit of tolerance to the sedative effects.


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