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Dropping acid may help headaches
    #6057137 -

Cluster headache sufferers say LSD can abort attacks.
by Arran Frood

We need to study the effect of powerful hallucinogens such as LSD (lysergic acid diethylamide) and psilocybin, the active ingredient in 'magic' mushrooms, on debilitating cluster headaches, researchers say.

Their study, which points towards the effectiveness of these drugs, is published in the journal Neurology1. It is the first formal look at reports of LSD's therapeutic benefits in nearly 40 years, says Andrew Sewell of the Alcohol and Drug Abuse Research Center at McLean Hospital in Belmont, Massachusetts. LSD was used extensively in psychiatric research in the 1960s, but as mainstream attitudes swung against 'acid', prohibitive measures made researching the beneficial effects of hallucinogens extremely difficult.

Cluster headaches are characterized by excruciating pain that lasts from fifteen minutes to up to three hours if left untreated. In the chronic form, attacks can happen up to eight times a day, with no period of remission lasting longer than a month. The condition is not fatal, but for some sufferers it is so horrific they commit suicide.

There is no cure, but sufferers are often given supplemental oxygen to ease an attack. Some are prescribed migraine drugs, but these may not work and the side effects are often extreme.

About five years ago, users of Internet message boards began swapping stories about chronic sufferers who gained two- to six-month periods of complete remission after one or two sub-hallucinogenic doses of LSD or psilocybin.

Sewell and John Halpern, both of the Alcohol and Drug Abuse Research Center, decided to investigate. They interviewed 53 cluster-headache sufferers around the world who had self-administered psychedelics in an attempt to alleviate their symptoms. Medical records were checked to verify that they did indeed suffer from cluster headaches.

Acid test

Their results are startling: the majority (85%) of psilocybin users report that it aborted attacks — better than oxygen, which stopped attacks for 52% of the patients surveyed. LSD and psilocybin were both better at preventing future attacks than conventional medicines.

The authors note there are many potential sources of bias in this type of retrospective analysis: sufferers may be more likely to recall and report good experiences than bad, for example. "Many retrospective studies have shown strong effects that evaporated when studied properly, so we are inclined to take a sceptical stance," says Sewell. Nonetheless, they say further research with controlled, randomized clinical trials is warranted.

In the meantime, many sufferers are convinced of the psychedelic drugs' utility. One patient, Bob Wold, started the Clusterbusters website to alert the community to the potential benefits — and dangers — of psychedelic drugs. For him, he says, a single dose every six months helps to stave off attacks. "I use psilocybin, and use just enough that I can feel the effects but don't really hallucinate as people would expect." The feeling, he says, is similar to what others might call a "two-beer buzz".

Head case

"I think there are better things to test," says Peter Goadsby, an expert in cluster headaches from the Institute of Neurology, University College London. But, he adds, "there seems to be a large number of people who think it's been useful to them, so it's a reasonable thing to consider."

Sufferers of the condition certainly need help, he adds. "It's the most appalling thing that can happen to you short of losing your family. That people are taking LSD and psilocybin is a reflection of the desperate straits they are in."

It is unclear how the drugs might work, though it is clear they affect the brain. LSD and psilocybin are types of amines called tryptamines, and their chemical structures are very similar to natural neurotransmitters such as serotonin. One conventional medicine for cluster headaches, Methysergide, is known to be chemically similar to LSD.

The study was partly funded by MAPS (Multidisciplinary Association for Psychedelic Studies), a non-profit alliance of scientists and campaigners that funds research into the therapeutic benefits of psychoactive drugs and lobbies for changes in US law.

The California-based MAPS is also helping to fund a study into the effects of MDMA (3,4-methylenedioxymethamphetamine, also known as ecstasy) on post-traumatic stress disorder, and another on its effects on end-stage cancer anxiety, on which Halpern is the lead scientist. And a MAPS-funded study into psilocybin as a treatment for obsessive compulsive disorder has been completed at the University of Arizona, Tucson.

Halpern and Sewell are now pushing for clinical trials of LSD and psilocybin. "We owe it to patients to determine whether this treatment works," says Sewell. "And we owe it to neurologists to provide them with accurate information so that they can effectively counsel patients."


http://www.nature.com/news/2006/060911/full/060911-5.html


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Every Animal Is Someone 🌱 watchdominion.org

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Re: Dropping acid may help headaches [Re: ivi]
    #6057164 -

everytime I read something like this I get really pissed off.

Why are mushrooms illegal again?

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Re: Dropping acid may help headaches [Re: ApJunkie]
    #6057254 -

Does anyone know the doseage they are giving for treatment? I can't imagine having a horrible headache and going through a trip with it.


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Message me for Mushroom Tinctures
Lion's Mane, Reishi, Turkey Tail, Chaga, Shiitake / Extracts / CBD Isolate, Oil
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Re: Dropping acid may help headaches [Re: ilus]
    #6057677 -

I would imagine less than two grams of mush. The one guy that used it once every six months said it was comparable to a two beer buzz. Which with my experience for me would be about 1-2 grams depending on the potency


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“Let’s put it this way – to lump psychedelic mushrooms into the same group as methamphetamine is like lumping the Bible into the same group as Mein Kampf.
I mean shit; they’re both books, right?”

Joe Rogan


R.I.P. - "Bones" - One of the greatest people I've ever had the pleasure of getting to know and become friends with.

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Re: Dropping acid may help headaches [Re: cookeman]
    #6057902 -

hmm... Marijuana is good for headaches and so is LSD. WOW, now if only we had rights to decide how we want to medicate ourselves. Hell yeah!!!

Yeah ill admit I just want the acid, and the Herb. Cant say ive had a headache in months, but OOOh it hurts right now, come on doc give me a script for a half sheet of Fractal, and a quarter sheet of Alice.

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Re: Dropping acid may help headaches [Re: ilus]
    #6059106 -

illustrain said:
Does anyone know the doseage they are giving for treatment? I can't imagine having a horrible headache and going through a trip with it.


sub-hallucinogenic


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Use the Fucking Reply To Feature You Lazy Pieces of Shit!

afoaf said:
Jim, if you were in my city, I would let you fuck my wife.

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Re: Dropping acid may help headaches [Re: ilus]
    #6059841 -

illustrain said:
Does anyone know the doseage they are giving for treatment? I can't imagine having a horrible headache and going through a trip with it.


My boss suffers from these headaches. He's taken as little as 1 gram cubensis to stop the head aches. Within 48 hours his headaches were over.


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YOUR EXPERIENCE WITH ANY GIVEN DRUG ISN'T THE DEFINITIVE MEASURE OF THE DRUGS EFFECTS.

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Re: Dropping acid may help headaches [Re: Ekstaza]
    #6059890 -

They need to perform an appropriate double-blind study with a placebo.

By themselves these survey based results don't hold much weight.


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...the whole experience is (and is as) a profound piece of knowledge.  It is an indellible experience; it is forever known.  I have known myself in a way I doubt I would have ever occurred except as it did.

Smith, P.  Bull. Menninger Clinic (1959) 23:20-27; p. 27.

...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.

Osmond, H.  Annals, NY Acad Science (1957) 66:418-434; p.436

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Re: Dropping acid may help headaches [Re: badchad]
    #6060219 -

if anyone ever watches the show house, in one episode he gave himself a migraine with nitroglycerin, for whatever reason he had, he ended up dropping acid to stop it. Doctors on acid WOOOO.


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Got a question about a substance?  Erowid might already have your answer! Have questions about the  mushroom experience? The  Tripper's FAQ may have your answer or someone else might have had your question before.
         
I know up on the top you are seeing great sights, but down at the bottom we, too, should have rights.
  - Theodor Seuss Geisel Dr. Suess

"I didn't come here to be easily understood" - Steve

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Re: Dropping acid may help headaches [Re: gdman]
    #6061113 -

This just in, water is wet!

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Re: Dropping acid may help headaches [Re: badchad]
    #6062054 -

badchad said:
They need to perform an appropriate double-blind study with a placebo.

By themselves these survey based results don't hold much weight.


:thumbup:


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Im a fucking spiral..

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Re: Dropping acid may help headaches [Re: BlindLemon]
    #6062429 -

I just love all the hedging the scientists do not to sound supportive of hallucinogen use.


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Center for Cognitive Liberty & Ethics

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