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Psychedelic-Assisted Psychotherapy combines psychedelics, music, therapy, and context. Within PAP, music acts as more than a backdrop. It may actively guide the psychedelic experience. Music may influence emotional, mystical, and other acute subjective experiences during PAP, which have themselves been associated with subsequent clinical outcomes. Early studies suggest that participants’ openness to, liking of, and resonance with music are associated with aspects of the psychedelic experience and short-term reductions in depression. Music may also provide temporal structure, emotional containment, and a means of modulating arousal.

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