Filament Health, Psilo Scientific Ltd. & 'stable' psilocin

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Manu_Ish
Black Morel

Registered: 08/21/22
Posts: 47
Last seen: 1 year, 9 months

Filament Health, Psilo Scientific Ltd. & 'stable' psilocin

#28223195 - 03/10/23 02:09 AM (3 years, 6 months ago)

I was reading an article on the Filament Health website pertaining to their naturally derived stabilized psilocin, which of course is proprietary.

Ascorbic acid induces the phosphatase enzyme in chicken embryos, for example.

My ascorbic acid concentrate is definitely converting psilocybin to psilocin.

The problem is that psilocin seems to degrade rapidly. Some studies say by as much as 90% in 7 days within blood samples. Even in urine it breaks down rather quickly. In the air it breaks down quickly,too.

Does anyone have any ideas on how Psilo Scientific Ltd. are stabilizing the psilocin for long term storage and use?

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herbstation
Child

Registered: 01/05/23
Posts: 222
Last seen: 7 months, 1 day

Re: Filament Health, Psilo Scientific Ltd. & 'stable' psilocin

[Re: Manu_Ish]
#28224904 - 03/11/23 09:45 AM (3 years, 6 months ago)

I found several articles online about crystalizing psilocybin from different solvents. There are a few crystal forms that require slightly different processes. They all talk about working under nitrogen. I think oxygen is the main issue. If you can make pure-ish crystal psilocybin, then dissolve it with an oxygen-free solvent, convert it into psilocin via enzymes under nitrogen, that might work. I assume we can eat the enzymes so there's your final product. Keep it in the fridge with a self healing lid and pull out doses with a syringe.

The degrading of psilocin is caused by oxidation which leaves the psilocin in a state where it will bind to itself, making a blue or green pigment. I don't know what other conditions could cause this, though, so oxygen may not be the only issue.

Crystallizing psilocin looks like a royal pain but it is apparently possible as well. It's in the Sandoz patent near the end.

Take that all with a grain of salt, I'm remembering college chem and I was pretty bad at it.

Cheers
Herb

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Expanding my mind until I can join the collective