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Stranger Reged: 08/30/04 Posts: 1049 |
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--> To those who experience anxiety on shrooms...If you take shrooms along with 70mg of pure thh or tetrahydroharmine, not only does it eliminate anxiety, add crystal clear clarity, increased euphoria, but the shroom trip is extended by an hour +, done it countless times myself, absolutely incredible gorgeous experience. Thh is a psychedelic sri not maoi found in cappi. Damn near perfect psychedelic combo....other than that mescaline is all ready the perfect psychedelic, drank cactus tea over 150 times over many years. I love that it lasts incredibly long allready. Sabnock said: "There may be some confusion surrounding THH for people. From my understanding, the form of THH found in the B. Caapi vine is purely a Serotonin reuptake inhibitor and ime it certainly feels that way, it doesn't have or at least isn't supposed to have MAOI properties, which that comes from the Harmine and Harmaline." Sabnock is a legend, read countless posts from him and he is indeed correct. Bardy said: Quote:Yes, that information is incredibly vague or unclear. The sentence is very vague in that it does not tell you it would take a severe overdose of THH to inhibit MAO-A. From Interprise chemical: "THH is a fluorescent indole alkaloid extracted from B. caapi that inhibits MAO-A and MAO-B with much weaker potency (IC50s = 74 nM and >100 μM, respectively) compared to its companion harmala alkaloids: harmaline (IC50s = 2.5 nM and 25 μM, respectively) and harmine (IC50s = 2 nM and 20 μM, respectively)" https://interpriseusa.com/produ Keep in mind, the lower the nM, the higher or stronger the activity. Reading those numbers, you would have to take 30 times the normal dosage of 100mg THH, or 30 x 100 = 3,000mg THH just to equal rima activity of 100mg of harmaline, and it takes at least 100mg of harmaline to activate DMT. That much THH would be an overdose and most likely kill a person. My max is 300mg of THH. It takes around 150mg of harmine to activate DMT, that would require 5500 mg of THH to do the same. --> If you remember 69ron, I was not around when he used to post, as I was at the mescaline king forum thenook.org for at least a decade (now extinct) he claimed that THH alone would activate DMT, this is completely un-true, this earned him or her a very bad reputation as people found out after his writing of this, that no such thing was possible. Bardy said: Quote:When you compare 4.3% harmine and 5.6% harmaline to 0.1% THH, you end up with next to nothing in the seeds as THH. There is absolutely no significant amount of THH in rue seeds, period...but you can make THH from harmaline in 1.5 hour. Even as a chemist, I spent months trying to make THH from harmaline without using exotic chemicals like TIHKAL, after months of failure, I went into a trance and was given a vision of how to complete the process I was stuck at using an over the counter chemical and explain how to make it simply in link below, I wanted humanity to know how to do this, as I feel it is extremely important. Hallucinogenic Plants in the Mediterranean Countries, Ioannis D. Passos, Maria Mironidou-Tzouveleki, in Neuropathology of Drug Addictions and Substance Misuse, 2016: Quote:https://www.sciencedirect.com/t Older Caapi is becoming close to extinct as harvesters have to go further and deeper into the Jungle...hence the over hundred spiritual centers in South America are having to harvest younger cappi with much less tetrahydroharmine, here in link below is an alternative to help conserve while it grows over many years: Traditional true Ayahuasca has always been (1) Caapi by itself or (2) Caapi with psychotria viridis or Diplopterys cabrerana. 12 reasons THH rocks and how to make her here: https://www.shroomery.org/forum Nillion, I'm not a vendor nor ever been, you might be thinking of 69ron, I am not 69ron. Lifelong chemist and researcher. Anyways, I cracked the code on how to make THH at home in only 1.5 hour, no exotic chemicals needed like in TIHKAL, more on this below. Bardy said: Quote:I'm a life long chemist, and know my chemistry, THH is 100% SRI and not a significant RIMA at all. Harmine is a RIMA, so is harmaline. THH is the 2nd highest alkaloid in caapi, in same family as ibogaine with a 10.5 hour half life with peak at 5.25 hours. Be careful if you buy THH from china (liftmode) as there have been reports of it not staining blue under UV (like real THH) but green, indicating harmaline is still in it. Dab a cue tip in vinegar, then take up a bit of your THH, smear on a paper plate, hold under uv light, if it glows blue you got pure thh, if any yellow or green it's contaminated with harmaline. Freedom said: Quote: Freedom, You will find no reports of THH + mushrooms or THH + LSD cause this is brand new cutting edge, but I've been doing it for many years, gorgeous experience, it's like taking a low dose of mescaline with you shrooms or acid. THH or tetrahydroharmine is the best kept secret in the psychedlic world: THH and how to make her (along with many trip reports of 300mg THH by itself): https://www.shroomery.org/forum More of my research (10 topics), on the cutting edge, and why dmt should always be taken with thh as found in true Ayahuasca: https://mycotopia.net/topic/111 2 minute formed HPBCD DMT liquid very bioavailable sublingually under tongue & outperforms DMT salts orally by many factors in personal trials, combo with tetrahydroharmine, Ayahuasca. Part 0: 12 reasons pure THH or tetrahydroharmine rocks (this post #1 in middle) Part 1: HPBCD complexed DMT experimental dosage, effects & duration, over 44 sublingual DMT experiences over a year's time (this post #1 at bottom). Many times stronger than oral DMT. Updated 1-1-2022. Part 2: Receptorome chart & explanation Part 3: Tetrahydroharmine (THH) effects --> Part 4: Tetrahydroharmine receptorome similarities to mescaline; potentiates cactus & safety note Part 5: Chemist Patrick Arnold's HPBCD prohormones & bloodwork studies part 6: Dr. Narang: "with sublingual" or "under the tongue" better than buccal, gingival & palatal, absorption of drugs through the sublingual route is 3 to 10 times greater than oral route and is surpassed by hypodermic injection. part 7: a little bit on my 70 Ayahuasca experiences, doses & visions part 8: New research: Morning glory contains 5 stimulating LSD-like drugs, soluble only in wine/alcohol, only sparingly soluble in water part 9: 20 minute visionary visit from a dead Aztec Shaman part 10: One way to make pure tetrahydroharmine part 11: From the archives of DMT world: How to easily extract 2.3g DMT from 170g bark using a 2 liter Erlenmeyer flask part 12: Out of print writings on the Divine Plant of the Incas, coca leaf visions...and writings on strong euphoria from coca leaf tea bags soaked in wine, forming orally active cocaethylene in the liver, discovered in 1994. Explains the popularity of Vin Mariani (coca leaf soaked wine) with both popes, Thomas Edison and countless celebrities. part 13: THH + mushrooms report from JKW. part 14: Multiple encounters with death & depression. Northerner said: Quote:Thank you Northerner. I've been taking dmt with THH for many, many years, here is a compilation of my 50 + trip reports with many pics of the 150mg harmine + 70-300mg THH + 90mg dmt true Ayahuasca capsules: https://www.shroomery.org/forum Since harmine has a half life of from 1 to 3 hours, I redose at the 1.5 hour to 2 hour point using only 75mg harmine + 90mg dmt in a single capsule again for a +4 moderately strong experience, as 1/2 the harmine dose is still active from the first dose. You don't have to add anymore THH since THH has a half life of 10.5 hours, peaking at around 5 hours. You can re dose as many times as you want, continues to work strongly. This gives me a total 4 hour strong trip that is easy to handle, with hours of afterglow. Going beyond 120mg DMT is not recommended, see my trip reports on page 2. I recommend crushing the dmt freebase into fresh aloe vera gel from fresh leaf (*almart carries fresh leaf in grocery section or buy on line, store excess gel in freezer as it only lasts 1 week in fridge, defrost more when needed) only as the polysaccharides in the fresh leaf increase the penetration of the dmt into the intestines by many factors, for an experience that can easily reach +4 to +5 and is all encompassing and super colorful just like real Jungle Ayahuasca, I've noticed no difference in strength between these zero nausea Ayahuasca capsules and real Ayahuasca brew I've prepared from caapi and Hawaiian psychotria. THH + mushrooms report from JKW: Quote: -------------------------------- Go to bottom of page 3 for an easy pan cyan estero strain grow similar to Asura's grow: https://www.shroomery.org/forum 50 trip reports in this thread. Modern research has determined that the pan cyan strain of mushrooms with their HIGH NORPSILOCIN + BAEOCYSTIN and related analogues content hit the adrenal receptors with as much force as MESCALINE or DMT, see chart below. Notice how just plain psilocin alone hits the 3 adrenal receptors (responsible for enhanced colors, euphoria, beauty and music enhancement) with lighter activity. Attached: Structure–Activity Relationships for Psilocybin, Baeocystin, Aeruginascin, and Related Analogues to Produce Pharmacological Effects in Mice, ACS Pharmacol. Transl. Sci. 2022, 5, 11, 1181–1196: https://pubs.acs.org/doi/10.102 by Grant C. Glatfelter*, Eline Pottie, John S. Partilla, Alexander M. Sherwood, Kristi Kaylo, Duyen N. K. Pham, Marilyn Naeem, Grant C. Glatfelter*, Eline Pottie, John S. Partilla, Alexander M. Sherwood, Kristi Kaylo, Duyen N. K. Pham, Marilyn Naeem, Vamshikrishna Reddy Sammeta Vamshikrishna Reddy Sammeta, Stacie DeBoer, James A. Golen, Elliott B. Hulley, Christophe P. Stove, Andrew R. Chadeayne, David R. Manke, and Michael H. Baumann. Pan cyan vs P. cubensis "They [Pan cyans] are so much cleaner! The trip is shorter but more intense. The visuals are just incredible. You feel very light compared to cubensis and the headspace is more manageable (at least at lower doses). "Most intense, euphoric, neon colorful trip that introduced me to pan cyan, most unlike any cubes I have ever had. Way preferred these over cubes. So deeply euphoric and extremely visual with saturated tropical neon colors. From then on I was hooked." "I didn't really expect how good the differences were from Cube to [Pan cyan] estero. The visuals weren't comparable at all and the euphoria was so wonderful. My 2g trip was literally the best substance experience of my life next to marriage and kids. 10 hours of pure bliss." "I strongly agree with starting with one-half gram dry. It was a much better experience than any cubes I've tried even at higher doses." "Cubes gave me mild nausea and made me feel 'shakey'. Not at all so with Pan cyans." "Less cartoony than cubes. More crisp neon geometric patterns. The trip also feels less tiring." "Copelandia [Panaeolus] cyanescens are far stronger than cubes and have a distinctly different feel." "I've eaten pan cyans around the 1g dose - to me it was like 3g of cubies in strength with a different quality to it." "IMO they [Pan cyans] are a lot better than cubes. No body noise and very intense and clear. More like LSD just a lot shorter. I don't cultivate many actives on a regular basis anymore, but out off all I have experienced to date, these are my favorite." "Pan Cyan (and Trops) are very much worth the effort!!! I have never eaten any Cubes that were as VISUAL as these are. Not to mention a little goes a LONG ways. Gram and a half of these little fellers will blister your brain!" "In my humble opinion, I think 1 gram of wet Panaeolus is even better than 1 gram of dry Cubensis, making them 10X more potent [?!?], in addition to the more positive and smooth experience, easier consumption due to amount and taste, and much less nausea." "My first experience [with Pan cyans] was wonderful! I definitely noticed a big difference in potency and the mood of the trip. I still remember how clean, visual and surreal everything felt. I felt absolutely no body noise or anxiety. They felt very natural to experience, nothing felt wrong if that makes sense." "Ok, so it's given that [Pan cyan] it's much stronger than cubensis. But I've noticed that there is a difference in the high. Why is that?" "There's something about Pan Cyan that induces something special that no cube could ever bring, it isn't that it's a clean feeling either - it's something that must deal with happiness in general - so whether it stimulates serotonin production or a mixture of neurochemicals for the best experience, I have had consistently positive experiences with each trip both physiologically and psychologically. I wonder if it has to do with other alkaloids or absence of alkaloids vs cubensis." "It is my personal view that Hawaiian Copelandia [Panaeolus] cyanescens offers the entheogen user a more enjoyable experience than the more easily cultivated Psilocybe cubensis. In fact I would place it in the premier cru of psychedelic plants, alongside the indigenous Liberty Cap (Psilocybe semilanceata) and the various DMT containing plants." General comments "They are the cleanest, smoothest, most peaceful mushroom vibe of all the species I have tried. Panaeolus cyanescens and tropicalis rank #1 in my book." "They are far and above the cleanest clearest and most potent mushrooms I have ever encountered, tread lightly with these guys." "SWIM has only consumed the Copelandia cyans (Hawaiian), and reputes them to be the best mushroom experience by far. Very clean trip, zero body load, clear head space." "The highs real clean. It reminds me of the Felix the cat acid from the 80s. Just smooth. With little body noise and extreme visuals. A calm lucidity that is like a slice of heaven." "First experience last night with Estero pan cyan. Truly mystical, amazing, and the most beautiful and gentle psychedelic experience to date. Truly a gift." "I also noticed that cyans have a very smooth comedown and longer duration. What could be the reason for this?" "Pans are no joke. Anyone who says LSD is more powerful than mushrooms has never done pans." -------------------------------- Other topics: Alchemy chemistry fun: Compilation of pan cyan or panaeolus cyanescens or copeandia cyanescens trip reports, crown jewel of mushrooms: https://www.shroomery.org/forum How to extract 2.4g dmt from 170g bark using a 2 Liter erlenmeyer flask (heat and break resistant), post #15: https://mycotopia.net/topic/111 Tetrahydroharmine or THH and how to make her, Caapi visionary feminine teaching spirit: https://www.shroomery.org/forum Zero nausea HPBCD or aloe vera enhanced penetration Ayahuasca capsules: https://www.shroomery.org/forum Cactus tea before waterpark to beat the heat: https://www.shroomery.org/forum How to make LSI or Lysergic Acid Isovaleraldemide (Greek Eleusis ancient LSD) at home from morning glory seeds (the priests used non poisonous claviceps paspali which grows on paspalum grass adjacent to Eleusis present day in the famous Rarian plane, same alkaloid profile as the sacred Mesoamerican morning glory): https://www.shroomery.org/forum Make your own 1-acetaldehyde LSD at home from LSD, very similar to ALD-52 or the real orange sunshine: https://www.shroomery.org/forum LSD high dose trip: 20 minute visionary visit from a dead Aztec Shaman: https://www.shroomery.org/forum On my very first pan cyan mushroom trip, where I went to a house music club tripping with friends, I viewed laser light patterns on the floor of the club, where the women danced, I believe the mushrooms showed me how to form never before seen patterns, as went I went home, over the next several months, I built my own 6 channel audio generator that when these combined frequencies (3 on x channel and 3 on y channel) were sent to a laser x and y galvanometer, were able to produce brand new laser patterns such as collapsing circles and spinning lines 360 degrees which looked beyond belief in the fog as 3-d, I then went on to market these laser scanners to clubs on the strip, and they were a huge success...I owe this creative invention to the mushrooms which sparked new creative energies, way beyond thought, from a higher source where the mushrooms tap into. My love for house music stems back to those days of visiting many clubs as an entertainment laser lighting fixture creator and programmer and making friends with the many DJ's. Over the summer myself and friends were lifeguards at the local water park. But on the weekends we went to parties or house music clubs. https://soundcloud.com/discover https://www.friskyradio.com/ https://jaytechmusic.podbean.co -------------------------------- Compilation of panaeolus cyanescens or pan cyan experiences & combo with THH or tetrahydroharmine, like organic psilocin LSD, extremely visual, music enhancing & super euphoric. myself: ---------- Very first pan cyan experience: 3 of us ate dried pan cyans on the way to a nightclub playing undergound house music. The road to the club turned into a rollercoaster of neon colors made of purple, yellow, green, super saturated, waving up and down in intense neon colors, just incredible. I looked at my left arm and it was covered in green Alien symbolic hieroglyphics, so wild! I looked off to the side into the sky and saw 3 alein hyperdimensional beings, small in stature looking back at me, made of purple and yellow colors...we stopped to peak inside the store with crystals inside along the way, all of the crystals in the shop had alien heads in them with open mouths and penetrating eyes, staring back at us, we saw aliens in all of the crystals! When we got to the nighclub, the woman collecting the $5 to get in, turned into a scary witch, we were all agasp, inside the club, we were some of the first to enter, so not crowded at all, the music sounded so bad ass, the videos playing in the addition rooms grabbed our attention. We each touched the girl's leg who went with us, who was tripping as well, felt like MDMA, the intensity of the touch was incredible. Most intense, euphoric, neon colorful trip that introduced me to pan cyan, most unlike any cubes I have ever had. Way preferred these over cubes. So deeply euphoric and extremely visual with saturated tropical neon colors. From then on I was hooked. I grow these following Gordotek's simple method further below, when fruiting the spawned trays with the sterile casing layer, I just leave cake pan trays out on a small fold out table with a Kvol hd3 3.5 liter ultrasonic cool mist humidifier pointed at all 3 trays on a timer 1/2 hour on, 1/2 hour off, pointed at all 3 trays on a table close to window in small room that get's warmer than rest of house, fruit just fine in open air. Very simple, nothing elaborate needed. The monsoon is also a great humidifier. I do use a flow hood however when transferring the grown out mycelium grain jars to the trays when mixing in with the pasteurized manure/straw (spawning stage), AND also later when removing the see thru cake lid covering the white mycelium grown out substrate in the cake pan when applying the sterile 1/4" casing layer. Picture at the very end of trays on table in open air for fruiting. They like a constant 77 degrees F from beginning to end, ie grain jar stage to fruiting stage. Prefer keeping the 3 grain jars and the 3 cake pans during the lid closed "mycelium substrate grow out" and "open lid, open air fruiting stage" on top of a VIVOHOME 10 Inch x 20.75 Inch Waterproof Seedling Heat Mat with included 40-108°F Digital Thermostat Controller. You could also use a greenhouse Martha tent with controllable temp and a monsoon humidifier with stretchable hose that reaches as high as 66" to the top of the inside of the 63" tall tent to direct humidity downwards to all the trays, only have to refill the monsoon every 2 days. Buy or make a Laminar flow hood, it's the best investment you will ever make. *** You can take these pan cyan at the same time as taking 150 to 250mg of pure tetrahydroharmine (not an MAOI or RIMA but a psychedelic SRI or serotonin reuptake inhibitor) and it feels like "organic psilo LSD", powerful combination with super heightened euphoria and visuals and huge powerful music enhancement, stimulating like LSD in combo with the THH, as THH has numerous similarities to mescaline and LSD. I have done this combo numerous times, one of my absolute favorite trip experiences. I can recommend pan cyans in combo with 150 to 250mg pure tetrahydroharmine, gives an experience that is extremely euphoric, intensely visual and spiritual, a lot like LSD when combined with the THH, one of my absolute favorites of all time. THH + mushrooms report from JKW: Quote: 1) bridgesii 600 gram to 800 gram pieces from around the core tea, 350 to 450mg plus mescaline in the tea = 11 out of 10 2) panaeolus cyanescens mushrooms in combo with 150 to 250mg THH, 6 hour incredible experience = 11 out of 10 3) LSD with bridgesii cactus combo = 11 out of 10 4) oral 200mg harmine + 200mg oral THH + sublingual under the tongue DMT, can re-dose under the tongue dmt every hour up to 3 hours = 11 out of 10 Gordotek's pan cyan grow: https://www.patreon.com/posts/n https://mycotopia.net/topic/110 https://www.shroomery.org/8695/ https://www.shroomery.org/8421/ https://www.shroomery.org/forum https://www.shroomery.org/forum https://www.shroomery.org/forum http://en.psilosophy.info/panae https://www.shroomery.org/forum https://mycotopia.net/topic/329 https://www.shroomery.org/8695/ https://www.shroomery.org/forum https://www.shroomery.org/forum How pure THH or tetrahydroharmine adds to the experiences, here are my experiences combining it with sublingual HPBCD DMT. What I do now is take 200mg of harmine and 200mg of pure THH orally, then 1 hour later once I feel the harmine and THH, I take sublingual HPBCD DMT (around 100mg) hold under tongue for 15 minutes, all dissolves, gives a 1.5 hour very strong extremely euphoric and visual experience, then I re-dose more sublingual DMT at the 1.5 hour point again, holding under tongue, continues to work at full strength, as the oral harmine has a half life of from 1 to 3 hours, continues to work for 3 hours to 5 hours. I way prefer taking DMT under tongue instead of orally, as zero nausea, goes straight to brain, no dizziness, the only way I use it, very bad ass this way. None of the negatives of oral Ayahausca. There is something about DMT moving thru the stomach that makes it nausea prone, dizzy, and weird and strange, this is all avoided by using it under tongue. The harmine lowers MAO in the brain for 3 to 5 hours, so you can use the dmt under tongue with many re-doses, as it prevents the DMT from being zapped by mitochondria in the brain. https://mycotopia.net/topic/111 https://mycotopia.net/topic/111 12 reasons pure THH or tetrahydroharmine rocks: -------------------------------- 0. THH is not an MAOI or a RIMA but a psychedelic serotonin reuptake inhibitor (SRI) found in caapi with many similarities to mescaline. She is a feminine teaching spirit. 1. Part 10 of the first linked paper above: shows how to convert harmaline to pure THH in 1.5 hour for the first time (very fast) with 75% yield. TIHKAL THH entry also achieved 75% yield. Post also shows how to dip a cue tip in vinegar to wet, take up a bit of the THH, smear on a paper plate to check the blue glow under blacklight to make sure it is pure. Any green in the glow means you still have un-converted harmaline, but follow instructions and you won't have any unconverted. --> Please do this UV check even if you source THH from China (liftmode paperwork indicates Chinese made), as there have been a few reports of it glowing green and not pure light blue with the vinegar swabbed UV check, indicating there is still harmaline in the THH, it would not be a good idea to take even light amounts of harmaline with shrooms, you want only pure THH...either make it yourself or source it from a reputable supplier. THH is an SRI and harmaline is a RIMA, completely different substances <-- 1. Dennis Mckenna Ph.D: page 115: Thus, tetrahydroharmine may prolong the half-life of DMT by blocking it's intraneuronal uptake, and hence, its inactivation by MAO, localized in mitochondria within the neuron. In my experience, THH doubles the half-life of DMT, so when used sublingually or orally, you get a full strong 90 minutes out of it with long afterglow. 2. She is in the same beta-carboline family as ibogaine. She is the 2nd highest alkaloid in Caapi. She has a 10.5 hour half-life with peak at 5.25 hours. 3. DMT only colors are subdued and dark, but THH brightens the DMT visuals: out of this world impossible bright neon colors are a trait of high dose oral tetrahydroharmine + moderate dose 60 to 70mg+ sublingual or oral HPBCD DMT: neon red-greens, neon orange-blues, neon purple-yellows. 4. DMT does not block serotonin on it's own, but THH does...this results in not only stimulation but euphoria in combo with the DMT: and real Ayahuasca visions become apparent...important teamwork. Ibogaine, LSD, mescaline, shrooms, 5-meo-dmt, bufotenin in Amazonian snuffs, all block serotonin, THH blocks serotonin. 5. THH has numerous similarities to mescaline, she is like the beta-carboline version of mescaline, few people have used her over 100mg. I have seen the receptorome chart for THH vs. mescaline. She not only blocks serotonin like mescaline, but agonizes all 3 adrenal receptors A1-A3 associated with beauty and aesthetic enhancement, just like mescaline. Beauty enhancement is "over the top" when THH is included, she is diamondlike shimmering in her beauty. Actresses on TV will look like dazzling glowing super-colorful cartoon versions of themselves (just like with high dose cactus tea) only if you include the THH. Researchers have called THH the "tryptamine of the beta-carboline world" and rightly so. 6. THH is found in average 150mg in a cup of Caapi based Ayahuasca tea, when 2 cups are drank by some of the more advanced members for evening at the vegetals (UDV, Santo Daime, Shuar Indian) people are consuming around 300mg of THH. 7. Music will only sound bad-ass incredible if you include from 150mg to 300mg oral THH with your sublingual or oral DMT. Listening to music on THH + DMT is like listening to music on high dose cactus tea: heavenly, infinitely beautiful music enhancement, every voice and instrument stands out on it's own, like hearing a song for the very first time. 8. This pure THH at 300mg all by herself is extremely visual, she's an isomer of a hormone like substance made in the brain naturally. 9. The entry in TIHKAL for 300mg THH is completely wrong, where the unexperienced person compares it to the effects of 100mg harmaline. She is nothing at all like harmaline, and like 69ron once said about the person's comment in TIHKAL, he or she would not be able to tell their ass from their elbow. I agree, what complete nonsense. Dr. Shulgin wrote that he never got the chance to try THH, but wrote that more studies on it are "badly needed." 10. professor8 (found here from 11/1/2010 he writes like a poet w/special powers of imagination & expression): Quote: Espiridion: Quote: 11. Trips (from here on 12/2/2011): Quote: The world is moving in the direction of the Left Brain: technology and science. What the world needs is to move in the direction of Right Brain development: empathy, spirituality, connectedness. Compounds like tetrahydroharmine in Caapi could be said to improve emotional intelligence. Is this component of caapi a smart-nutrient for the right side of the brain? you be the judge. At 300mg of THH all by itself, there are heavy open-eyed tracers like lightening flashes, and hours of teaching closed eye visions that start with colored sparkles and fireworks (red, green, yellow, blue) that dart around and progress into full-fledged way-beyond 4k visions with eyes closed that are not only static but often animated like slow and high speed movies, but all one monochrome color like green or blue for me, when you add DMT, the visions then become colored and patterning on animals for example will display their associated colors, DMT also adds on to or builds on top the THH visions, expanding them, but the teachings and insights & visions are credited to the Vine, just as Gayle Highpine writes in linked paper: 12. Gayle Highpine (Ayahuasca researcher): http://www.ayahuasca.com/amazon Quote: Page 154 of "Various Alkaloid Profiles in Decoctions of Banisteriopsis Caapi, 2005": https://kodu.ut.ee/~hellex/aya/ Quote: Dr. Callaway wrote in "The Entheogen Review": Quote: THH blocks serotonin, just like all the major natural oral psychedelics, serotonin blocking results in stimulation, breaking down of barriers and filters, direct access to divine spiritual world, increased visionary power, major beauty, color and music enhancement, euphoria in combo with the DMT. DMT does not block serotonin but requires THH in combo to do this, important teamwork. 5-ht1a agonism is inhibitory and results in serotonin blockage (over 80% of brain 5-ht). Thomas S. Ray's study shows a value of 3.57 at SERT for Ibogaine (4.00 is max). Ibogaine has been shown to inhibit serotonin transporter (SERT) noncompetitively, in contrast to all other known inhibitors, which are competitive with substrate. Ibogaine inhibits both serotonin and dopamine reuptake transporters, it is an SDRI or serotonin & dopamine reuptake inhibitor. THH or tetrahydroharmine also inhibits the serotonin reuptake transporter (SERT). In contrast, as an example, Cocaethylene (coca leaf tea bags soaked in wine, the orally active & potent ingredient formed in the liver from cocaine + ethanol in the 1860's "Vin Mariani" wine popular with both Popes, Thomas Edison and scores of other famous people) increases the levels of serotonergic, noradrenergic, and dopaminergic neurotransmission in the brain by inhibiting the action of the serotonin transporter, norepinephrine transporter, and dopamine transporter. These pharmacological properties make cocaethylene a serotonin-norepinephrine-dopamin Dr. Nichols (Purdue Scientist authorized to study LSD, from Heffter.org LSD paper): https://www.heffter.org/wp-cont Quote: waylitjim (April 2005): https://mycotopia.net/topic/334 -------------------------------- Ever wonder why many consider the Panaeolus experience incredibly unique? "They are the cleanest, smoothest, most peacefull mushroom vibe of all the species I have tried. Panaeolus cyanescens and tropicalis rank #1 in my book." "the highs real clean . its reminds me of the phelix the cat acid from the 80s . just smooth . with little body noise and extreme visuals . a calm lucidty that is like a slice of heaven" "Pan Cyan (and Trops) are very much worth the effort!!! I have never eaten any Cubes that were as VISUAL as these are. Not to mention a little goes a LONG ways. Gram and a half of these little fellers will blister your brain!" Psilocybin and psilocin are part of the tryptamine family. Their chemical structure bears close resemblance to that of serotonin. "The occurrence of tryptamine derivatives in Panaeolus cyanescens, also known as Copelandia cyanescens, from Australia, Hawaii and Thailand were investigated. All 70 collections contained psilocin, serotonin and urea. Those from Hawaii were also relatively rich in psilocybin, whereas the species from Australia and Thailand were virtually exempt of this compound. It is not unthinkable that the ability to biosynthesize psilocin in a number of Panaeolus is a consequece of a genetic accident: initially, these members of the genus probably produced more or important qualites of serotonin until a mutation conferred the ability to produce 4-hydroxylated tryptamines. So far, not other genus or species has been found to accomplish this feat!" Partial reference from: Stijve, T. (1992): Psilocin, psilocybin, serotonin and urea in Panaeolus cyanescens from various origin waylitjim: ---------- Even with lower levels of psilocybin, Panaeolus are still more potent than Cubensis. Why? Because by weight psilocin is around 1.4 times more potent than psilocybin. The primary active ingredients of psilocybe mushrooms are psilocybin and psilocin, and to a lesser extent baeocystin and norbaeocystin. The ratio of psilocybin to psilocin varies from species to species. The primary difference is that psilocin is unstable and it breaks down in the presence of oxygen. If the mushrooms are dried correctly and kept cold, they should suffer very little psilocin break down. Psilocybin on the other hand has been found in a 115-year old mushroom sample. It is believed that after injestion, psilocybin is easily converted into psilocin and that the pharmacological properties of both compounds are the same. Asura: ----- Pan cyans are faster than cubes and 3-4x more potent. 2g is a full on DMT-like, level 5 trip, so while your yield is less...your magic content is more...and the trips are insanely good. It's the most potent species anyone has a chance of doing indoors with significant yield. They are harder to fruit but there are plenty of people killing it right now with low tech setups. I would love to help out on the science...but I am not tripping right now. I could probably recruit some folks on the official pan thread, though. The link in my sig details how I cultivate them, but an ideal time line is something like: 1. Agar wedge to LC. 5 days to grow out. 2. LC to substrate = 10 days to grow out 3. substrate to tray = 5 days to recover. 4. Case and fruit = 5 days until first pins. So, wedge to first pins in 25 days. About 3-5 days to harvest. 2nd-x flushes will also be done in 3-5 days. If someone could figure out how to get the yield and make it as easy as cubes, I'm pretty sure most people would grow these. I am averaging about 32g dried for one tray (3 quarts substrate), which doesn't sound like much - but that is 16 full on level 5 trips from that. If I lemon tek 2g of pans it is overpowering. Like forced VR or something. My eyelids cease to exist and the inside of my head and the outside of my head are one space. Time loops. Living 1000 life times. Alien landscapes. Vision quests. You name it. It's pretty fucking intense and scary to be honest...I don't do it that often ![]() A 1g dose is heavenly, though, and much more manageable. Tea makes it easier. Lemon tek is like taking a strong cube trip and compressing it. The trip moves really, really fast. It's speeded up. The come up is very disorienting. Like not only are you are tripping hard, you're also in a barrel going over Niagara Falls. Gordotek: --------- 3 DIC 2020 A LAS 21:26 New simple method (TEK) for growing Panaeolus cyanescens (aka Copelandia cyanescens, Hawaiians, blue meanies, Pans and Pan cyans): https://www.patreon.com/posts/n Estero strain available here: https://sporesfast.com/product- Q: Can I buy a kit for this? A: YES! See: https://www.patreon.com/posts/6 June 10 at 7:09 PM, https://www.patreon.com/posts/6 Comparison of Estero (Pan cyan) and Albino Penis Envy (Cubensis) mushrooms via Thin Layer Chromatography: https://www.patreon.com/posts/6 -------------------------------- I will create a video explaining how to do this type of analysis, but for now I just wanted to show everyone a comparison between these species. Albino Penis Envy (APE) is widely considered to be one of the most potent cubensis cultivars, it was heavily represented in the latest psilocybin cup (if you want to see my comments/critique of the cup, click the link and scroll down to the bottom where comments are shown, to see comments on a phone you may have to tap settings (in chrome for example)->desktop view). So how does APE stack up against Estero (pan cyan)? Each dot in the picture above represents a chemical compound (these are labeled on the left). They are in two vertical columns, so the left side from top to bottom is all Estero, right side is APE. Starting with the two most important, look at the psilocybin and psilocin content - quantification is not precise, but you can estimate based on spot size and darkness, the Estero cultivar is approximately three times as potent as APE (and it would have easily blown all other entries out of the water had it been submitted to the psilocybin cup). This should be a reminder to all to dose appropriately (pan cyan holds the record for most potent mushroom species in the world as per published research). If you normally take 3 grams of cubensis, try 1g of Estero. It is always better to start with a lower dose and see how you respond before trying anything higher (you may want to start with just 0.5g). There is NO PRIZE for taking the highest dose, in fact there is no documented benefit of any dose beyond about 35mg psilocybin equivalent, just more fear & anxiety for most people. But there's more to it than just triple the psilocybin and psilocin, Estero also contains baeocystin (hard to see, but its there), urea (quite a bit), and serotonin. None of these compounds can be seen at all in APE. Could these be partly responsible for the difference in anecdotes from user experiences on Estero? Here are some comments people have sent on this subject: "I strongly agree with starting with one-half gram dry. It was a much better experience than any cubes I've tried even at higher doses." "Cubes gave me mild nausea and made me feel 'shakey'. Not at all so with Pan cyans" "Penis Envy is and has been overrated. I think any other well sourced Cube is just the same. It’s that cultural conditioning at play." "lol who needs cubes when you can have Cyanescens! I’ve blessed a few people with them and they are now believers lol." "When Estero kicked in, I wasn’t disappointed. At one point I forgot I ate Cyanescens and thought I was on a DMT ride! As often happens to me on DMT I was 'connected' to some kind of power cord or machine umbilical that was coming from my wall straight towards me and plugged into my third eye! And I felt the presence of a cosmic nurse at my side. Like she had her hand in my shoulder reassuring me all was ok! Then I was like “f*** I ate mushrooms this ain’t a DMT trip” ![]() "I've taken enough cubes to know Estero is different... 2 grams. Most amazing experience of my life. 10 hours. And another two hours of happiness watching TV and talking about my experience with my wife. In the end I just want to thank you. No comparison." "OMG, OMG, O. M. G. Had my first deeply religious experience on 2g [estero] yesterday. I have never felt anything like it in my life. It was truly incredible." "I ended up taking a 1 gram of Estero since I’m used to taking 3-4 grams of cubensis. Man…you were not kidding about the potency of these. 1 gram easily felt like 4-4.5 grams of cubensis to me. These were by far the best visuals on mushrooms I’ve ever had. Also, the euphoria was quite intense, and giggle sessions were uncontrollable. All in all, I love pan cyans and they’ll likely be my go to. I’ll likely still grow cubensis for microdosing as well as less potency for sharing with others." "Experienced people do sometimes doubt ones sanity trying to explain just how deep Estero gets on what some call a "micro dose" the pan experience for me is the most rewarding substance I've ever ingested and half reduced my dose and frequency of use to fine tune the benefits, plus stopped using synthetic drugs completely and have been experiencing recovery i didn't really know I need but pretty sure i do." "I didn't really expect how good the differences were from Cube to estero. The visuals weren't comparable at all and the euphoria was so wonderful. My 2g trip was literally the best substance experience of my life next to marriage and kids. 10 hours of pure bliss." [Gordo note: 2g is too much for most people, be cautious] "Funny because I went to an Ayahuasca ceremony in May and the Shaman told me to start growing pans... he said, “Cubes are for the people. Pans are for the elevated.” "First experience last night with Estero pan cyan. Truly mystical, amazing, and the most beautiful and gentle psychedelic experience to date. Truly a gift." "There's something about Pan Cyan that induces something special that no cube could ever bring, it isn't that it's a clean feeling either - it's something that must deal with happiness in general - so whether it stimulates serotonin production or a mixture of neurochemicals for the best experience, I have had consistently positive experiences with each trip both physiologically and psychologically. I wonder if it has to do with other alkaloids or absence of alkaloids vs cubensis" One of this years funniest/best psychedelic reveals was the guy who actually came up with Penis Envy (the best selling cubensis cultivar of all time), when interviewed by Hamilton Morris essentially said (my paraphrase) 'Eh, it's still just a cube, and cubes don't do it for me. I find the Cyanescens far superior (they have entities)!' Haha. So the guy who created the most popular cubensis cultivar in the world doesn't even like cubensis. Eventually I think most in the grower community will come to prefer other species. I would still like to see some reputable published research comparing user experience by species (this is challenging to do but worth a try). As an aside, if you listen to that Hamilton interview, the PE guy says a lot of "out there" things that deserve to be challenged, every so called claim of "supernatural powers" has always failed rigorous testing and he is no exception. The psychedelic community has a long history of nonsense associated with it, and as far as I'm concerned, its time to do things differently, and I will always call out the nonsense. I have plenty more to say about Casteneda, astral projection, and more, but don't want to get side tracked. Love life, stay strong, and be well. https://www.patreon.com/posts/2 gordotek FAQ https://www.patreon.com/posts/6 New "Grass Lover" mushroom grow kit (for pan cyan or any other grass lover species) https://sporesfast.com/product/ estero syringe March 5 at 8:40 AM New "Grass Lover" mushroom grow kit (for pan cyan or any other grass lover species) I'm really excited about this because I have been trying to get a vendor to make kits suitable for my pan cyan TEK for more than a year and no one seemed able or willing to do it, people have been asking me where they could buy the substrate, etc. and I had no good source UNTIL TODAY! Midwest grow kits finally put together a kit that matches my recommended specifications. As far as I know, they are the ONLY vendor out there that is selling a kit like this. I'm also very pleased with where they priced it (currently just $35). Their kit includes properly pasteurized manure/straw based substrate (3 hour hot water immersion bath pasteurization process) with separate casing mix and the kit even includes the cake pans with clear lids. So with this kit, all a person will need is the grain spawn and a humidifier (note that they even sell a pretty cool looking humidifier with a long bendable hose that has great reviews so if you need a humidifier you might consider that too). Midwest set me up with an affiliate link which I am very grateful for, any sales that happen after clicking my link help support this channel but I'm not promoting this just because I have an affiliate link, this is genuinely the only kit of its kind on the internet that I know of and the price is unbeatable too. https://midwestgrowkits.referra If the link doesn't take you directly to it, type "grass lover" into the search bar (the humidifier and grain jars should show up at the bottom of the grass lover kit page as well if you want those items). Note: I wouldn't promote this without testing it first, they sent me an early version of the kit, I will probably make a full video review of the kit and add to this post when I have more to share, but for now I'll just say that everything looks fantastic! There was enough substrate in the kit to make 3 standard size cake pans, and the Estero cultivar RIPPED though this substrate reaching full colonization in 4-5 days with no signs of contamination. Looks to me like they got it right. So someone who wanted to simplify the process of growing pan cyans could just order some sterile grain jars (Midwest also sells those), order a spore syringe (as far as I know, only one vendor sells Estero spore syringes) just inject the grain jars, wait for colonization, order the grass lover kit, dump the substrate from the kit into the cake pan that also comes with the kit, dump the colonized grains on top of that, mix, cover with clear lids, wait for colonization (preferably in warm temps 75-85F), then remove the clear lids and add the casing mix from the kit, humidify on a timer or spray down heavily several times per day, and you should get nice yields. Couldn't be much easier than that. Edited by tregar (01/21/24 09:43 AM)
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