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InvisibleveggieM

Registered: 07/25/04
Posts: 17,504
The Morel Foils Dangerous Grapefruit-drug Interactions
    #9698598 - 01/29/09 05:47 AM (15 years, 1 month ago)

Edible Fungus Foils Dangerous Grapefruit-drug Interactions
January 29, 2009 - Medical News Today

Scientists in Florida report that adding an edible mushroom-like fungus to grapefruit juice may help to reduce the serious side effects that can occur when people taking certain prescription drugs drink grapefruit juice. Their study is in the January 14 edition of the ACS' bi-weekly Journal of Agricultural and Food Chemistry.

In the study, Kyung Myung and colleagues explain that furanocoumarins (FCs) - chemicals found in grapefruit and some other citrus - block a key enzyme critical for metabolizing, or breaking down, certain prescription medications. This "grapefruit/drug" interaction - sometimes called the "grapefruit effect" - can turn normal drug doses into toxic overdoses. Researchers have tried to remove FCs using chemical, physical and microbiological methods. Myung and colleagues, for example, had previously discovered that an inedible fungus can be used to remove most of the FCs from grapefruit juice.

Now they report that the edible fungus Morchella esculenta, which is from the same major fungal group as the previously tested inedible fungus, removed most of the furanocoumarins from the grapefruit juice. It also reduced grapefruit juice's inhibition of the enzyme by 60 percent.

Dried M. esculenta also worked, leading the researchers to suggest that it could be useful in removing the compound from grapefruit juice and identifying the specific components in the fungi that bind to furanocoumarins.

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Offlineneopet nub
Stranger


Registered: 11/29/08
Posts: 2,408
Last seen: 13 years, 4 days
Re: The Morel Foils Dangerous Grapefruit-drug Interactions [Re: veggie]
    #9698640 - 01/29/09 06:12 AM (15 years, 1 month ago)

Cubensis work much better. :thumbup:


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Ego death from weed!

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OfflineStonewall
Mad Scientist


Registered: 08/31/08
Posts: 165
Loc: MI, USA
Last seen: 8 months, 1 day
Re: The Morel Foils Dangerous Grapefruit-drug Interactions [Re: neopet nub]
    #9698992 - 01/29/09 08:47 AM (15 years, 1 month ago)

the day we stop learning is the day we start dying.. I love seeing new fungus medical research :mushroom2:


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The ultimate good is like water. It nourishes all things without trying to, content with the lowly places people disdain.

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OfflineCptnGarden
fuck this site

Registered: 05/13/04
Posts: 11,945
Last seen: 14 years, 10 months
Re: The Morel Foils Dangerous Grapefruit-drug Interactions [Re: neopet nub]
    #9699876 - 01/29/09 12:39 PM (15 years, 1 month ago)

Quote:

neopet nub said:
Cubensis work much better. :thumbup:




Cubensis suck :thumbup:

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OfflineParadox.Matrix
Stranger
Male


Registered: 12/24/08
Posts: 49
Loc: Toronto, Canada
Last seen: 14 years, 9 months
Re: The Morel Foils Dangerous Grapefruit-drug Interactions [Re: CptnGarden]
    #9701251 - 01/29/09 05:47 PM (15 years, 1 month ago)

nothing better then a pan of fried morels


--------------------
"What you see when you look at me is not my face, it's much more, when will you humans learn that the body is just the arbitrary physical manifestation of our spirits. This idea transcends racist ideologies; see life is comparable to that of a car, the body compromises the wheels, gears, the engine is the Brain, but the man in the seat is the spirit, the Soul. Sometimes you run out of gas or wreck, but is that life? you simply get out, get into another car or go home"

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