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Anonymous

what do shrooms do to your head
    #954410 - 10/12/02 04:24 AM (18 years, 11 months ago)

other than make you see things and what not, what does it do to your brain.....i guess you could call them side effects or long term effects.....im just curious....


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InvisibletrendalM
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Re: what do shrooms do to your head [Re: ]
    #954428 - 10/12/02 04:37 AM (18 years, 11 months ago)

Mushrooms contain the tryptamines Psilocin, Psilocybin (the phosphate ester of Psilocin) and to a lesser degree Baeocystin.

Psilocybin is broken down by the body into psilocin, which is several times more potent than psilocybin. Psilocin is structurally similar to the neurotransmitter serotonin. When you take shrooms the psilocin enters your brain and begins to attatch to certain serotonin binding sites in your brain (the 5-HT-2a site, I think).

Now for whatever reason (no one is really sure yet) this causes you to "trip" and have all the associated effects (hallucinations and the psychedelic experience, as well as some physical effects like dilated pupils).

As far as anyone knows, and there are decades of research into this, there are no long-term physical effects from mushrooms (psilocin). Psilocin, like LSD, is very fragile. It is almost entirely metabolized and excreted by your body within 24 hours and can not even be detected within a matter of days. Psilocin does not cause any known damage to your brain or any part of your body. It is one of the safest drugs known to man.


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Once, men turned their thinking over to machines in the hope that this would set them free.
But that only permitted other men with machines to enslave them.


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OfflineAnnoA
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Re: what do shrooms do to your head [Re: ]
    #954671 - 10/12/02 08:45 AM (18 years, 11 months ago)



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OfflineLOPHO.MP
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Re: what do shrooms do to your head(don't worry) [Re: ]
    #954760 - 10/12/02 11:13 AM (18 years, 11 months ago)


That is a very good question Replica.
Obviously you care what you put in your body and what effects it has. (some people really don't give a shit)

OK. Pharmacology, chemistry and neurology are not my strong point. I'm more into the social sciences, anthropology, sociology etc... So, my point is: there are human cultures that have been using mushrooms for thousands of years. It is very likely that humans have been using mushrooms since pre-historic times.
For me this is the ultimate proof of a drug that is compatible with humans. If someone tells me something about how psilocybin has a molecular nature that makes it metabolize in the brain....etc. etc. it does not mean much to me. However, if I can see that humans have been using this substance for millenia that I can understand.

If you are worried about side effects of something don't worry about mushrooms. If I were you I would be more worried about things that humans have not been exposed to for thousands of years. For example: synthetic chemicals in our food, and all this other shit that is just being invented.

So, think about the side-effects of the artificial flavors in that neon colored candy you are eating and don't sweat the mushrooms!

Good Luck!


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---Still Searching---


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OfflineArisEve
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Re: what do shrooms do to your head [Re: trendal]
    #954850 - 10/12/02 12:59 PM (18 years, 11 months ago)

You cant go wrong when you induldge in the more natural things in life... They dont grow for shits... They grow because they were ment to be eaten! shroom on heeh.


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Simple pleasures in life are only to momentarily distract you from the obviousness of lifes reality...

-ArisEve



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InvisibleNox
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Re: what do shrooms do to your head [Re: ]
    #956460 - 10/13/02 07:01 AM (18 years, 11 months ago)



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[The above post is made by a fictional character and is intended for amusement only.]


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InvisibleXlea321
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Re: what do shrooms do to your head(don't worry) [Re: LOPHO.MP]
    #956631 - 10/13/02 11:13 AM (18 years, 11 months ago)

For me this is the ultimate proof of a drug that is compatible with humans.

Alcohol, tobacco and opium are all pretty ancient too. Although tobacco in it's natural form doesn't appear to cause the same problems cigarettes do and opium is pretty harmless apart from the possibility of addiction.

Having said that I think psilocybin/psilocin are two of the safest compounds there is.


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Don't worry, B. Caapi


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InvisibletrendalM
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Re: what do shrooms do to your head [Re: ArisEve]
    #956935 - 10/13/02 02:45 PM (18 years, 11 months ago)

Don't think that just because something is "natural" it is safer than "artificial"...

Datura is natural but it is also extremely dangerous and deaths from datura poisoning are not all that uncommon. On the other hand there is LSD which is synthetic but like psilocin has never been found to cause damage to the human body.


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Once, men turned their thinking over to machines in the hope that this would set them free.
But that only permitted other men with machines to enslave them.


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InvisibleGalvie_Flu
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Re: what do shrooms do to your head [Re: trendal]
    #957032 - 10/13/02 03:34 PM (18 years, 11 months ago)

r


Edited by shaos (04/09/11 10:33 PM)


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Anonymous

Re: what do shrooms do to your head [Re: Galvie_Flu]
    #957047 - 10/13/02 03:40 PM (18 years, 11 months ago)

That doesnt count, he was a freak!


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InvisibleXlea321
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Re: what do shrooms do to your head [Re: Galvie_Flu]
    #957147 - 10/13/02 04:22 PM (18 years, 11 months ago)

Do we really know the LSD caused this centrum? Sounds pretty unlikely seeing as LSD is thousands times less toxic to the human body than aspirin.


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Don't worry, B. Caapi


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Offlinedjjoel
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Re: what do shrooms do to your head [Re: Xlea321]
    #957192 - 10/13/02 04:44 PM (18 years, 11 months ago)

Shrooms, Alcohol, Weed, Opium.. drugs of this kind are perfectly fine for you if you use them in moderation. Too much of any drug is not good, but not enough is also not fun :P Just keep that in mind and youll be fine!


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gg!


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OfflineTrauM
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Re: what do shrooms do to your head [Re: trendal]
    #957633 - 10/13/02 07:57 PM (18 years, 11 months ago)

Yes correct shrooms are one of the safest drugs known to man, but only physically (brain, body, health).

That does not account for mentally (thoughts, actions, procedures), lets not forget how equal they both are for safety issues.

Peace


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Oh what a tangled web we weave when we practise to deceive..


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InvisibletrendalM
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Re: what do shrooms do to your head [Re: TrauM]
    #960153 - 10/14/02 05:56 PM (18 years, 11 months ago)

In reply to:

Yes correct shrooms are one of the safest drugs known to man, but only physically (brain, body, health).

That does not account for mentally (thoughts, actions, procedures), lets not forget how equal they both are for safety issues.




Entirely true. The danger lies in how your mind (psychologically speaking) handles the trip. Some people probably just can't handle the psychedelic experience.

In reply to:

not true. i was reading that some kid with an adrenal gland tumor ate some LSD without knowing he had the tumor, and he died when his adrenal gland produced too much adrenalin. the autopsy found this out.




Do you have a reference for this? It's very possible to die from too much adrenalin, that's what happens when a person "scares themself to death". Too much adrenalin can easily cause a heart attack along with many other problems. However the LSD would not be the direct cause of death. He probably had a bad trip and got scared. Fear causes release of adrenalin. If his adrenal gland was malfunctioning then I suppose it's possible that the trip scared him to death.

It's not the same thing as LSD being toxic or harmful in any physical way.


--------------------
Once, men turned their thinking over to machines in the hope that this would set them free.
But that only permitted other men with machines to enslave them.


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Anonymous

Post deleted by Anno [Re: trendal]
    #960772 - 10/14/02 09:27 PM (18 years, 11 months ago)



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InvisibletrendalM
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Re: what do shrooms do to your head [Re: ]
    #960953 - 10/14/02 10:23 PM (18 years, 11 months ago)

MDMA does cause massive release of serotonin as well as inhibition of reuptake, so yes you lose a lot of serotonin when you do ecstacy which is why some people feel depressed, or hungover, afterwards.

Psilocybin (mushrooms) and LSD do not cause a release of serotonin and they do not inhibit reuptake. They act like serotonin in the brain and attatch themselves to some of the same receptors as serotonin. Because no extra serotonin is released and reuptake still functions you will not lose much (if any at all) serotonin while on these drugs.

Chemically they are very non-toxic and do not damage cells in the body. Some experiments have shown possible chromosome damage from LSD, but the concentration of LSD placed directly in blood required to cause the damage was far above the levels of asprin or caffeine that cause the same damage. Medically these chemicals are classified as non-toxic.


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Once, men turned their thinking over to machines in the hope that this would set them free.
But that only permitted other men with machines to enslave them.


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Anonymous

Post deleted by Anno [Re: trendal]
    #961123 - 10/14/02 11:19 PM (18 years, 11 months ago)



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InvisibleXlea321
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Re: what do shrooms do to your head [Re: ]
    #961673 - 10/15/02 01:46 AM (18 years, 11 months ago)

I think the latest research has shown that the idea of "E releasing serotonin" was just bad science that the government latched onto. There are people who have used E 1000 times plus who have more serotonin than people who have never taken E. Serotonin appears to naturally vary in different people.


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Don't worry, B. Caapi


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InvisibleGalvie_Flu
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Re: what do shrooms do to your head [Re: Xlea321]
    #963082 - 10/15/02 03:16 PM (18 years, 11 months ago)

if you use shrooms too often, sometimes some individuals develop curley hair


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InvisibletrendalM
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Re: what do shrooms do to your head [Re: Xlea321]
    #963098 - 10/15/02 03:19 PM (18 years, 11 months ago)

Your brain produces more serotonin all the time, so just because a person has more serotonin than someone else doesn't mean that person hasn't released a hell of a lot more serotonin.


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Once, men turned their thinking over to machines in the hope that this would set them free.
But that only permitted other men with machines to enslave them.


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Offlinespliffguru
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Re: what do shrooms do to your head [Re: Galvie_Flu]
    #963108 - 10/15/02 03:23 PM (18 years, 11 months ago)

Nothing is truly safe.


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There was a point to this message, but it has temporarily escaped the chronicler's mind


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InvisibleXlea321
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Re: what do shrooms do to your head [Re: trendal]
    #963131 - 10/15/02 03:29 PM (18 years, 11 months ago)

The government backed scientists produced pictures of brains with low serotonin and said this was because they'd taken E. Low serotonin was evidence of "brain damage" and the reason why people were "depressed".

It now turns out that there are people who have taken E over 1000 times who show more serotonin in brain pictures than people who've never taken it.


--------------------
Don't worry, B. Caapi


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OfflineTVEye
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Re: what do shrooms do to your head [Re: Xlea321]
    #963390 - 10/15/02 05:03 PM (18 years, 11 months ago)

Well, it's actually pretty thoroughly established that MDMA works by releasing and inhibiting the reuptake of serotonin and dopamine. That's not just the result of a government-backed study; that's just what scientific examinations have shown. In fact, Dancesafe has a nice little slide show that demonstrates exactly what MDMA does to the brain. And the hangover is due to a) reduced serotonin and dopamine levels and b) the fact that MDMA is pretty hard on your body. It's not an increased tolerance to serotonin - I don't think you can actually increase or decrease your tolerance to that neurotransmitter. It's the fact that you have significantly less serotonin in your system than you did before taking the drug - hence the whole postloading thing, so you can reestablish the balance MDMA upset as quickly as possible.

In any case, yeah, psilocin doesn't act in a way remotely similar to MDMA in the brain. They're not related chemically, and they don't do the same things.


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If you're cold, you're dead; if you're cool, you're halfway there - Chuck Dukowski


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Re: what do shrooms do to your head [Re: TrauM]
    #963876 - 10/15/02 08:21 PM (18 years, 11 months ago)

I indulged in mushrooms a lot early this year. Every weekend... After a perticularly bad trip i had some issues with irational anxieties and some other wierd stuff. Ive worked these problems out myself and they no longer bother me. I was really worried about my mental health for a while tho.

Whether shrooms caused it, brought it out early, or was not connected at all im not sure, im pretty sure shrooming evrey weekend didnt help.


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This is the only time I really feel alive.


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OfflineTeKHeAD009
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Re: what do shrooms do to your head(don't worry) [Re: LOPHO.MP]
    #966490 - 10/16/02 06:17 PM (18 years, 11 months ago)

In reply to:

If I were you I would be more worried about things that humans have not been exposed to for thousands of years.




Ya, actuially after everything I've read about mushrooms, I'm more concerned with driving my car and sniffing all those (toxic?) fumes that our vehicles put out. Like you said LOPHO.MP chemicals being used as preserviatives in our food. Even deoderant I'm more concerned about then mushrooms. They believe that arisol deoderant may be one cause of alztimers. The aluminum in it screwes up the brain.


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InvisibletrendalM
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Re: what do shrooms do to your head(don't worry) [Re: TeKHeAD009]
    #966512 - 10/16/02 06:22 PM (18 years, 11 months ago)

In reply to:

If I were you I would be more worried about things that humans have not been exposed to for thousands of years.




Humans have been exposed to tobacco and alcohol for thousands of years...


--------------------
Once, men turned their thinking over to machines in the hope that this would set them free.
But that only permitted other men with machines to enslave them.


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