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Offlinehightimesreader
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Registered: 07/18/06
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Is Psilocybin metabolized into Psilocyin or vise versa?
    #7853318 - 01/09/08 12:16 PM (16 years, 23 days ago)

Psilocybin -> Psilocyin once eatin correct? Stomach acid should convert the molecule into Psilocyin correct?

HTR


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InvisibleMad_Larkin

Registered: 11/29/07
Posts: 18,606
Re: Is Psilocybin metabolized into Psilocyin or vise versa? [Re: hightimesreader]
    #7853332 - 01/09/08 12:19 PM (16 years, 23 days ago)

As far as I know, you are correct.


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OfflineCoaster
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Re: Is Psilocybin metabolized into Psilocyin or vise versa? [Re: Mad_Larkin]
    #7853562 - 01/09/08 01:09 PM (16 years, 23 days ago)

Psilocin is the pharmacologically active agent in the body after ingestion of psilocybin or psychedelic mushrooms.

Psilocybin is rapidly dephosphorylated in the body to psilocin which acts as a 5HT2A, 5HT2C and 5HT1A agonist. It's effects are thought to come from it's ability to mimic serotonin (5-HT) and thereby activate serotonin receptors in the brain.

Psilocin has no significant effect on dopamine receptors (unlike LSD) and only affects the norephenephrine system at very high dosages.

Psilocin half-life ranges from 2 to 3 hours


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