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lysergicide
Aurora Borealis


Registered: 12/16/05
Posts: 1,863
Loc: 41.8861° N, 12.4851° E
Last seen: 9 days, 8 hours
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this feels different...
#7663156 - 11/21/07 01:55 PM (16 years, 2 months ago) |
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this salvia feeling, this vast expanse. i haven't tried salvia in a long time, but this still feels different, it feels distant and cascading; yet overwhemingly warm and beautiful. at other times it made me feel as if i were dead, but right now i just feel an overwhelming stoning sensation.
i know this is it, but why it feels so different, i don't know.
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Individual
Bass Addict


Registered: 12/20/06
Posts: 6,666
Loc: Reality Loophole
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Re: this feels different... [Re: lysergicide]
#7663190 - 11/21/07 02:02 PM (16 years, 2 months ago) |
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Maybe it feels different because you are different from the last time you tried it?
-------------------- THE PHILOSOPHY OF LIBERTY <---
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Robo
R Series 66Y
Registered: 05/08/07
Posts: 14,861
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Re: this feels different... [Re: lysergicide]
#7663340 - 11/21/07 02:42 PM (16 years, 2 months ago) |
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The Salvia dimension is a strange one...
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lysergicide
Aurora Borealis


Registered: 12/16/05
Posts: 1,863
Loc: 41.8861° N, 12.4851° E
Last seen: 9 days, 8 hours
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Re: this feels different... [Re: Robo]
#7663369 - 11/21/07 02:52 PM (16 years, 2 months ago) |
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it is strange, indeed.
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TripityDooDaDay
Prick


Registered: 09/14/06
Posts: 2,046
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Re: this feels different... [Re: lysergicide]
#7663966 - 11/21/07 05:23 PM (16 years, 2 months ago) |
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Salvia is strange. There is always a familiar feel to me but the trips can vary more than imagination it seems at times.
I wonder if some of the difference you just experienced has anything to do with the 5-HTP you mentioned starting?
Don't forget to update us on this THREAD when you feel like it.
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Merkin
neep.



Registered: 07/04/03
Posts: 27,537
Loc: Ass Flavoured Pie Factory
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salvinorin A is not a seretonin agonist.
-------------------- Wheels of cheese wheeels of cheeeeese!!!
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redgreenvines
irregular verb


Registered: 04/08/04
Posts: 37,532
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Re: this feels different... [Re: Merkin]
#7666234 - 11/22/07 09:07 AM (16 years, 2 months ago) |
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It is not the shape of a serotonin agonist, but the indirect action is not known. all they know is that the KOR binding sites show salvinorin-A binding, but indirectly from there, no experiments have been done. Specifically, raised serotonin levels have not been evaluated in relation to a KOR binding event, but such elevated levels may actually be the case.
Such an experiment should be devised, but it is difficult to design at this time, short of flash freezing subjects and controls at 1 minute, 2 minutes, 3 minutes... then mollecular assaying specific sites known to be serotonin active during psychedelic events. Naturally mice should be used.
anyway until such tests are done - all we know is a binding site, and that amounts to next to nothing.
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lysergicide
Aurora Borealis


Registered: 12/16/05
Posts: 1,863
Loc: 41.8861° N, 12.4851° E
Last seen: 9 days, 8 hours
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so last night i broke through and it was incredibly familiar from what i was used to.
before, it was a mere stoning sensation with distinct visuals and it gave me 2 hours of feeling weird.
last night, i broke through with incredible accuracy and i didn't know what to do or how to react. it was horrifying. i loved it.
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