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Drewwyann
Slayer of ticks



Registered: 10/30/06
Posts: 4,077
Loc: Atlantis
Last seen: 10 years, 3 months
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How long do SSRIs last?
#7461349 - 09/27/07 05:58 PM (16 years, 4 months ago) |
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I plan to trip with my girlfriend in the woods sometime before it starts to get cold around here, and before all of the leaves begin to fall.
She takes SSRIs, and i was wondering, how long does she have to be off of them in order for their effects to wear off at least mostly? Im doing some research on it, and i can't seem to find too much.
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 Anyone need a glass pipe? : http://www.facebook.com/profile.php?id=100002435158931 Love powerfully  
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QuantumMeltdown
Space Monkey




Registered: 10/31/01
Posts: 4,962
Loc: Ft. Lauderdale, FL
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Re: How long do SSRIs last? [Re: Drewwyann]
#7461501 - 09/27/07 06:31 PM (16 years, 4 months ago) |
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You really shouldn't discontinue your medications without a doctors order. Don't you think if shes on psych meds shes on them for a reason? Maybe she shouldn't be doing mushrooms.
-------------------- -QuantumMeltdown Total abstinence is so excellent a thing that it cannot be carried to too great an extent. In my passion for it I even carry it so far as to totally abstain from total abstinence itself. -Mark Twain "The time has come the walrus said, little oysters hide their heads, my Twain of thought is loosely bound I guess its time to Mark this down, Be good and you will be lonesome Be lonesome and you will be free Live a lie and you will live to regret it That's what livin' is to me That's what livin' is to me" Jimmy Buffett
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denots87
Shroomerite



Registered: 11/17/06
Posts: 125
Loc: B-Town
Last seen: 13 years, 2 months
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Depends on alot of things. SSRIs have half life's, ie how long the drug will stay in your body just like THC has. The medication specifically will determine the half life (prozac has a short half life so its out of your body sooner, compared to Effexor or other SSRI's which take longer).
Research the EXACT medication she is on, not just a general SSRI search as many SSRIs act and work differently on the brain and will interact different with boomers. I would strongly advise against discontinuing an anti depressants for more than a day, like a missed a dose to prevent any complications from mild to serious withdrawal (again this is all based on the person, everyone reacts differently). I've been taking SSRI's for 10 years now finding the spot to trip can be tricky, but is doable. Simple advice: Skip the medication on the day or day before you two plan on tripping, then continue the meds the next day, and enough the trip and awesome foilage
Peace and good trips
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skroomadoom
master of theskroomaverse



Registered: 07/16/07
Posts: 428
Loc: GA
Last seen: 14 years, 19 days
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I'm on SSRIs but I still trip all the time. It really doesn't seem to effect my tripping all that much. YMMV, but I would have her try tripping without going off her meds if you can help it.
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Drewwyann
Slayer of ticks



Registered: 10/30/06
Posts: 4,077
Loc: Atlantis
Last seen: 10 years, 3 months
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Re: How long do SSRIs last? [Re: skroomadoom]
#7461685 - 09/27/07 07:08 PM (16 years, 4 months ago) |
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QuantumMeltdown, I know my girlfriend very very well and I am 100% confident that she will be fine on mushrooms. She is very intelligent, and is a very sane person. One of the most sane i have met to date. But than you for the concern.
And denots, thank you for the info. I've been trying to find this out for quite a while.
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 Anyone need a glass pipe? : http://www.facebook.com/profile.php?id=100002435158931 Love powerfully  
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badchad
Mad Scientist

Registered: 03/02/05
Posts: 13,372
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Re: How long do SSRIs last? [Re: Drewwyann]
#7461695 - 09/27/07 07:10 PM (16 years, 4 months ago) |
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While knowing the half-life of a drug is a good start, it doesn't necessarily indicate a reversal of the cellular effects of the drug.
-------------------- ...the whole experience is (and is as) a profound piece of knowledge. It is an indellible experience; it is forever known. I have known myself in a way I doubt I would have ever occurred except as it did. Smith, P. Bull. Menninger Clinic (1959) 23:20-27; p. 27. ...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely. Osmond, H. Annals, NY Acad Science (1957) 66:418-434; p.436
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Drewwyann
Slayer of ticks



Registered: 10/30/06
Posts: 4,077
Loc: Atlantis
Last seen: 10 years, 3 months
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Re: How long do SSRIs last? [Re: badchad]
#7461748 - 09/27/07 07:23 PM (16 years, 4 months ago) |
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well she is taking zoloft (sertraline) and wellbutrin (bupropion). Wellbutrin is a reuptake inhibitor of dopamine, so i dont believe that it would have any effect on psilocybin or psilocin. The sertraline would however.
Badchad, you have just crushed my hope. But in a very informative way.
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 Anyone need a glass pipe? : http://www.facebook.com/profile.php?id=100002435158931 Love powerfully  
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CrackRockSteady
~~~~~~~~~~~~~~~~~~~shoa



Registered: 04/01/07
Posts: 78
Last seen: 16 years, 4 months
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Re: How long do SSRIs last? [Re: Drewwyann]
#7461897 - 09/27/07 08:03 PM (16 years, 4 months ago) |
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The half-life would be the easiest thing to examine and assess, but keep in mind that things like Wellbutrin XL, SR or any other time-release form will have a longer half-life. What badchad said is very true though, and it gets to a point where you just have to try it an see.
I wouldd tend to agree that going off of them for 2 days (max) couldn't hurt. Wellbutrin doesn't seem to have as bad a withdrawl as an SSRI (I've been on both, effexor and wellbutrin). I went for 3 days with no Effexor (SNRI btw), with no noticable effects. Supposedly Effexor has one of the worst withdrawls, BUT everyone is different.
Good luck...
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