Home | Community | Message Board

MushroomMan Mycology
This site includes paid links. Please support our sponsors.


Welcome to the Shroomery Message Board! You are experiencing a small sample of what the site has to offer. Please login or register to post messages and view our exclusive members-only content. You'll gain access to additional forums, file attachments, board customizations, encrypted private messages, and much more!

Shop: Original Sensible Seeds Autoflowering Cannabis Seeds   Kraken Kratom Kratom Capsules for Sale   Mushroom-Hut Mono Tub Substrate   Unfolding Nature Unfolding Nature: Being in the Implicate Order

Jump to first unread post Pages: 1
InvisibleveggieM

Registered: 07/25/04
Posts: 17,504
Anti-fungus Drug Induces Hallucinations
    #7440355 - 09/22/07 12:22 PM (16 years, 4 months ago)

Study Says Pfizer Anti-fungus Drug Can Induce Hallucinations
September 22, 2007 - theday.com

CHICAGO - Physicians, nurses and other health care providers should be aware that patients receiving intravenous treatment with the antifungal drug voriconazole may develop a range of neurological side effects, including auditory and visual hallucinations, according to a report presented at the 47th annual Interscience Conference on Antimicrobial Agents and Chemotherapy.

Voriconazole, sold under the trade name Vfend, is a relatively new drug used to treat serious fungus infections, such as invasive mold infections and invasive candidiasis. Many of these patients are extremely ill and are receiving several different drugs, which makes it difficult to distinguish the side effects of specific drugs from the symptoms of the underlying illness.

To estimate the frequency and seriousness of voriconazole side effects, Dr. Dimitrios Zonios and colleagues at the National Institutes of Health in Bethesda, Maryland, evaluated patients in an ongoing prospective study that was assessing voriconazole toxicity. The researchers focused on side effects of the central nervous system, which are not well characterized for the drug.

Between March 2006 and June 2007, the researchers evaluated 66 cancer patients who were being treated with intravenous voriconazole at their institution. Careful interviews and toxicity evaluations were conducted for each patient.

Zonios's group identified eight patients who experienced hallucinations. All of these patients had visual hallucinations and four also had auditory hallucinations. In six patients the hallucinations began within 24 hours of receiving the drug, and after 1 and 2 weeks of treatment in the other two patients.

The hallucinations quickly disappeared after the drug was stopped in six patients and after the dosage was reduced in the other two. No residual effects were noted.

The visual hallucinations frequently consisted of seeing people or scenes. One patient reported seeing flying objects, another saw scenes of Montana and New York City, and a third patient saw a giant "Wookie" from the movie Star Wars bending over his bed.

The auditory hallucinations often consisted of hearing voices and music, and one patient reported hearing TV commercials.

All of the patients remained oriented, alert, and understood that the hallucinations were not real.

The researchers were not able to identify any other drugs that were likely to have caused the hallucinations and none of the other drugs interacted voriconazole to cause an increase in blood levels of the antifungal drug. Drug levels were within the dose recommendations in all eight patients when symptoms began.

Other neurological effects seen in the group as a whole included visual disturbances, such as blurry vision, in 15 patients; sensitivity to light in 10; and a decreased ability to concentrate in 2 patients. Another 5 developed signs of liver damage.

Zonios and colleagues conclude that visual and auditory hallucinations are "not uncommon" side effects of voriconazole and suggest that health care professionals offer reassurance to patients, should this complication occur.

The possible association between voriconazole-related hallucinations and high blood levels of the drug is currently being investigated, the investigators added.


Extras: Filter Print Post Top
OfflineSkeeblix
Dave Thomas
Male


Registered: 01/28/07
Posts: 1,745
Loc: Wendy's
Last seen: 8 years, 3 months
Re: Anti-fungus Drug Induces Hallucinations [Re: veggie]
    #7440390 - 09/22/07 12:40 PM (16 years, 4 months ago)

Oh no! You might see something that isn't! there! Quick, pull it from the shelves before someone enjoys it or jumps out a window, or something! :rolleyes:

The only thing I see wrong with this medicine is the liver damage it's possibly at the root of.


--------------------
This post approved by:


Premedman1 said:
:lol: I just shat my pants.


Extras: Filter Print Post Top
OfflineTurricaN
Grasshopper
Registered: 03/17/05
Posts: 823
Loc: Amersfoort, Netherlands
Last seen: 8 months, 10 days
Re: Anti-fungus Drug Induces Hallucinations [Re: Skeeblix]
    #7440456 - 09/22/07 01:05 PM (16 years, 4 months ago)

It depends on whether they're speaking of real hallucinations (the kind that datura causes) or pseudo-hallucinations (the kind that psilocybin and LSD cause).

If it's the former (and by the sound of the article, it is), then I would agree with the article that there is reason to be concerned about the drug.


Extras: Filter Print Post Top
OfflineTHEBats
FuturePsychopharmacologist
Male

Registered: 03/18/05
Posts: 1,268
Loc: Florida
Last seen: 12 years, 7 months
Re: Anti-fungus Drug Induces Hallucinations [Re: TurricaN]
    #7440496 - 09/22/07 01:18 PM (16 years, 4 months ago)

Quote:

TurricaN said:
It depends on whether they're speaking of real hallucinations (the kind that datura causes) or pseudo-hallucinations (the kind that psilocybin and LSD cause).

If it's the former (and by the sound of the article, it is), then I would agree with the article that there is reason to be concerned about the drug.




Well gee what else would you call seeing a wookie bending over your bed?


Extras: Filter Print Post Top
OfflineArcofaJourney
Internaltransportationdevice
 User Gallery

Registered: 10/05/05
Posts: 582
Loc: your imagination
Last seen: 6 years, 7 months
Re: Anti-fungus Drug Induces Hallucinations [Re: THEBats]
    #7440594 - 09/22/07 01:51 PM (16 years, 4 months ago)

Quote:

THEBats said:
Quote:

TurricaN said:
It depends on whether they're speaking of real hallucinations (the kind that datura causes) or pseudo-hallucinations (the kind that psilocybin and LSD cause).

If it's the former (and by the sound of the article, it is), then I would agree with the article that there is reason to be concerned about the drug.




Well gee what else would you call seeing a wookie bending over your bed?




i call that Saturday night.


Extras: Filter Print Post Top
InvisibleGanzig
It's for the street cred
Male User Gallery


Registered: 11/29/06
Posts: 8,206
Loc: Oregon Flag
Re: Anti-fungus Drug Induces Hallucinations [Re: TurricaN]
    #7440764 - 09/22/07 02:56 PM (16 years, 4 months ago)

Quote:

TurricaN said:
It depends on whether they're speaking of real hallucinations (the kind that datura causes) or pseudo-hallucinations (the kind that psilocybin and LSD cause).

If it's the former (and by the sound of the article, it is), then I would agree with the article that there is reason to be concerned about the drug.




yeah, what the hell does that mean? I have never consumed the loco weed as they call it from my hood, but what is real and what is pseudo?


--------------------
I must keep reminding myself of this.
I must keep reminding myself of this. I must keep reminding myself of this.
I must keep reminding myself of this.


Extras: Filter Print Post Top
OfflineLittleman

Registered: 10/01/06
Posts: 446
Last seen: 9 months, 17 days
Re: Anti-fungus Drug Induces Hallucinations [Re: Ganzig]
    #7440788 - 09/22/07 03:07 PM (16 years, 4 months ago)

reall hallucinations is straight up seeing things, objects etc. that arent there.
lsd and mush produce visuals, which are more like a distortion of reality.


--------------------
"Well Right after the 4th hit he was so far gone he puked all over him self. He had no clue that he threw up on him self and was finger painting in it on his stomach."
- Mudnpool

NZ Psilocybe Hitlist:
Subaeruginosa-Weraroa-Semilanceata
-Subsecotioid - Angulospora - Tasmaniana - Alutacea


Extras: Filter Print Post Top
InvisibleTTT
Cultivate the inside
 User Gallery

Registered: 08/07/06
Posts: 4,340
Re: Anti-fungus Drug Induces Hallucinations [Re: Littleman]
    #7440807 - 09/22/07 03:15 PM (16 years, 4 months ago)

I always thought that hallucinations are when you see and hear things that you believe to be there, but arent.

Pseudo-hallucinations are when youre aware that the things youre seeing/hearing arent real.


Extras: Filter Print Post Top
Offlinedirtworshipper
Sitting in the heart cave
Male User Gallery


Registered: 05/12/07
Posts: 2,060
Loc: at The Guru's lotus feet
Last seen: 3 years, 3 months
Re: Anti-fungus Drug Induces Hallucinations [Re: ArcofaJourney]
    #7441179 - 09/22/07 05:20 PM (16 years, 4 months ago)

Quote:

ArcofaJourney said:
Quote:

THEBats said:
Quote:

TurricaN said:
It depends on whether they're speaking of real hallucinations (the kind that datura causes) or pseudo-hallucinations (the kind that psilocybin and LSD cause).

If it's the former (and by the sound of the article, it is), then I would agree with the article that there is reason to be concerned about the drug.




Well gee what else would you call seeing a wookie bending over your bed?




i call that Saturday night.




:rofl:


--------------------

“You've got as many lives as you like, and more, even ones you don't want.” - George Harrison


Extras: Filter Print Post Top
Invisiblemonkeyheaven
Male


Registered: 07/09/07
Posts: 964
Loc: yonder
Re: Anti-fungus Drug Induces Hallucinations [Re: THEBats]
    #7441611 - 09/22/07 07:37 PM (16 years, 4 months ago)






Well gee what else would you call seeing a wookie bending over your bed?




time to buy the wife a razor?


Extras: Filter Print Post Top
OfflineTurricaN
Grasshopper
Registered: 03/17/05
Posts: 823
Loc: Amersfoort, Netherlands
Last seen: 8 months, 10 days
Re: Anti-fungus Drug Induces Hallucinations [Re: Ganzig]
    #7442843 - 09/23/07 03:57 AM (16 years, 4 months ago)

Quote:

Ganzig said:yeah, what the hell does that mean? I have never consumed the loco weed as they call it from my hood, but what is real and what is pseudo?



If you believe that the hallucination is real, then it's a real hallucination, otherwise it's a pseudo-hallucination.

Consider the difference between normal and lucid dreaming.


Extras: Filter Print Post Top
OfflineJohn0809
Sporehut King
Male

Registered: 01/28/06
Posts: 183
Last seen: 16 years, 18 days
Re: Anti-fungus Drug Induces Hallucinations [Re: TurricaN]
    #7443777 - 09/23/07 11:11 AM (16 years, 4 months ago)

Ahh the difference is eaither tripping and knowing it or tripping
and
going to the hospitol jumping out a window and such because whatever it is that is making you trip also makes you forgot you ate it or makes you think it has nothing to do with the effects your feeling


--------------------
Check out my Site!


Extras: Filter Print Post Top
Offlineemit
Trippy 70'sSci-Fi Movie
Male User Gallery


Folding@home Statistics
Registered: 06/20/07
Posts: 131
Loc: my place ;)
Last seen: 1 year, 5 months
Re: Anti-fungus Drug Induces Hallucinations [Re: John0809]
    #7445286 - 09/23/07 07:09 PM (16 years, 4 months ago)

it can get scary if you dont know you are tripping


--------------------
yes...


Extras: Filter Print Post Top
Jump to top Pages: 1

Shop: Original Sensible Seeds Autoflowering Cannabis Seeds   Kraken Kratom Kratom Capsules for Sale   Mushroom-Hut Mono Tub Substrate   Unfolding Nature Unfolding Nature: Being in the Implicate Order


Similar ThreadsPosterViewsRepliesLast post
* Tokyo govt to crack down on unregulated drugs AnnoA 903 0 01/10/04 06:33 AM
by Anno
* Two plead guilty in drug smuggling case motamanM 1,368 0 12/24/03 02:52 PM
by motaman
* Rave drugs seized motamanM 2,643 1 05/09/03 10:42 AM
by Learyfan
* Melbourne, Australia: Legal drugs are overdosers' choice AnnoA 995 0 04/26/04 04:20 AM
by Anno
* WHY DEADLY DRUG IS STILL PERFECTLY LEGAL motamanM 4,061 13 05/13/04 06:38 AM
by Asante
* Youths risk death in latest drug abuse trend motamanM 11,225 18 01/27/17 09:32 AM
by Themanwiththeplan
* Sizeable mushroom bust said to be one of biggest on record *DELETED*
( 1 2 all )
cerealrat 12,933 30 07/13/04 12:38 AM
by Anno
* Drug task force is making mark AnnoA 1,532 0 03/31/04 08:27 AM
by Anno

Extra information
You cannot start new topics / You cannot reply to topics
HTML is disabled / BBCode is enabled
Moderator: motaman, veggie, Alan Rockefeller, Mostly_Harmless
3,084 topic views. 0 members, 9 guests and 8 web crawlers are browsing this forum.
[ Show Images Only | Sort by Score | Print Topic ]
Search this thread:

Copyright 1997-2024 Mind Media. Some rights reserved.

Generated in 0.025 seconds spending 0.006 seconds on 14 queries.