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InvisibleveggieM

Registered: 07/25/04
Posts: 17,504
Weak Marijuana Works as Well as High-Dose THC Pills
    #7128685 - 07/04/07 01:48 PM (16 years, 7 months ago)

Weak Marijuana Works as Well as High-Dose THC Pills
July 3, 2007 - bbsnews.net

WASHINGTON, D.C. -- Two just-published scientific studies provide further evidence that medical marijuana laws do not increase marijuana use, and that even weak marijuana works as well as (and in some ways better than) high-dose Marinol, the THC pill sometimes touted as a substitute for marijuana.

In a study published online by the International Journal of Drug Policy, researchers from the Texas A&M Health/Science Center analyzed two sets of data designed to monitor emerging drug-use trends, the Arrestee Drug Abuse Monitoring System (ADAM) and the Drug Abuse Warning Network (DAWN), from locations where medical marijuana laws have been put into effect. ADAM is based on urine tests of adult and juvenile arrestees, while DAWN tracks mentions of drug use in records of hospital emergency departments. Both sets of data, from before and after implementation of the medical marijuana laws, were looked at in a "time-series analysis" based on the premise that "if the law in question has an impact (either positive or negative) then the series of observations that follow its implementation will have a different slope or trend than those that occurred before."

In both sets of data -- from California, Colorado, Oregon, and Washington -- the researchers found no change in the trend after medical marijuana laws went into effect. "Consistent with other studies of the liberalization of cannabis laws," they wrote, "[the results] indicate that medical cannabis laws do not increase use of the drug."

A second study, in the Journal of Acquired Immune Deficiency Syndromes and also published online ahead of its appearance in print, compared the THC pill marketed as Marinol to smoked marijuana supplied by the National Institute on Drug Abuse. While both medications proved effective at stimulating appetite, reducing the need for other medications to combat gastrointestinal problems, and helping patients sleep, it took eight times the recommended dose of Marinol to roughly equal the efficacy of weak marijuana, with 3.9 percent THC, supplied by NIDA. According to the White House Office of National Drug Control Policy, the average THC content of marijuana seized by law enforcement during the first quarter of 2007 was 8.5 percent.

The study's "double-dummy" design successfully prevented patients from identifying which active treatment they were receiving at any given time, overcoming a common problem with marijuana and THC studies. Although researchers characterized the efficacy of Marinol and whole marijuana in the study as "similar," only whole marijuana produced statistically significant improvements in patients' levels of hunger, desire to eat, and quality of sleep. Marijuana also produced a higher daily caloric intake than even the highest Marinol dose, although in this small and relatively brief study, that difference did not reach statistical significance.

Neither treatment produced significant negative side effects. Strikingly, when patients were given a series of tests measuring learning, memory and other cognitive functions, neither marijuana nor oral THC produced any significant changes in performance.

Gorman DM and Huber J Charles Jr. Do Medical Cannabis Laws Encourage Cannabis Use? International Journal of Drug Policy, 2007 Vol. 18 no. 3, pp. 160-7.

Haney M, Gunderson EW, Rabkin J, Hart CL, Vosburg SK, Comer SD, and Foltin RW. Dronabinol and Marijuana in HIV-Positive Marijuana Smokers: Caloric Intake, Mood, and Sleep. J Acquir Immune Defic Syndr. 2007 Jun 21; [Epub ahead of print]

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Offlinehighdroponics
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Registered: 11/14/06
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Re: Weak Marijuana Works as Well as High-Dose THC Pills [Re: veggie]
    #7128769 - 07/04/07 02:08 PM (16 years, 7 months ago)

the reason marinol is petty much useless is because it ONLY contains a synthetic THC, whereas marijuana contains THC, CBD, and CBN, without the other two chemicals its not really going to provide the needed effect...but this is just what ive come to realize through a debate with a doctor.


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Dr :ronpaul: says to stop trying to treat the side-effects of big government and focus on the core issues. End the Federal Reserve/audit the gold reserves at Fort Knox, abolish the IRS, end all wars and occupancies, stop the building of an empire that will inevitably fail, and cut all unconstitutional federal programs. Put the power back in the peoples' hands by ending this nanny-state.

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InvisibleDNKYD
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Registered: 09/23/04
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Re: Weak Marijuana Works as Well as High-Dose THC Pills [Re: highdroponics]
    #7128866 - 07/04/07 02:38 PM (16 years, 7 months ago)

Useless to to the patients as an effective medicine, but very useful to the pharmaceutical companies that need to sell 10x more so the patients can get the desired effects.

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Offlinehighdroponics
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Re: Weak Marijuana Works as Well as High-Dose THC Pills [Re: veggie]
    #7128906 - 07/04/07 02:57 PM (16 years, 7 months ago)

^ not only that but with the other chemicals in these pills, it will cause other 'sickness'(since all pharmaceutical meds cause sickness/side effects) and then people will pin it down on marijuana....which this stuff isnt, its a synthetic form of THC created in a lab by chemists.


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Dr :ronpaul: says to stop trying to treat the side-effects of big government and focus on the core issues. End the Federal Reserve/audit the gold reserves at Fort Knox, abolish the IRS, end all wars and occupancies, stop the building of an empire that will inevitably fail, and cut all unconstitutional federal programs. Put the power back in the peoples' hands by ending this nanny-state.

Edited by highdroponics (07/04/07 02:58 PM)

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OfflineEllis Dee
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Re: Weak Marijuana Works as Well as High-Dose THC Pills [Re: highdroponics]
    #7130338 - 07/04/07 11:47 PM (16 years, 7 months ago)

The thing I fail to understand is that this pill is promoted as being effective for anti-nauseas for AIDS wasting syndrome, but of you have to take it orally it can't be effective because the patient will puke it back up.


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"If the foundations be destroyed, what can the righteous do."-King Solomon

And there was war in heaven: Michael and his angels fought against the dragon; and the dragon fought and his angels,

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InvisibleOneMoreRobot3021
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Registered: 06/06/03
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Re: Weak Marijuana Works as Well as High-Dose THC Pills [Re: Ellis Dee]
    #7131533 - 07/05/07 08:01 AM (16 years, 7 months ago)

In Canada they've developed "Sativex" which solves that problem by putting THC into a spray form that you spray into the lining of your mouth.


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Acid doesn't give you truths; it builds machines that push the envelope of perception. Whatever revelations came to me then have dissolved like skywriting. All I really know is that those few years saddled me with a faith in the redemptive potential of the imagination which, however flat, stale and unprofitable the world seems to me now, I cannot for the life of me shake.

-Erik Davis

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OfflineProt
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Registered: 01/27/02
Posts: 104
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Re: Weak Marijuana Works as Well as High-Dose THC Pills [Re: OneMoreRobot3021]
    #7132337 - 07/05/07 12:15 PM (16 years, 7 months ago)

Canada did not devlope the spray.. brits did. its just that they are about the only ones that support it.

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Invisiblejeetered
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Registered: 07/07/06
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Re: Weak Marijuana Works as Well as High-Dose THC Pills [Re: veggie]
    #7133178 - 07/05/07 03:33 PM (16 years, 7 months ago)

it's still easier to vape or smoke a nug. cheaper by far, and does wonders for the environment. The pulp waste could produce plenty of textiles, of course, we've all heard this before, so i won't go further.

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InvisibleOneMoreRobot3021
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Registered: 06/06/03
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Re: Weak Marijuana Works as Well as High-Dose THC Pills [Re: jeetered]
    #7133613 - 07/05/07 05:06 PM (16 years, 7 months ago)

Anyway, the reason medical marijuana users should be able to SMOKE their product is that the pain relief accompanied by smoking a joint tends to come on immediately. Many medical mj users will have a joint rolled, and when symptoms of their disease and assorted medications flare up, they take two or three hits, then roach it, then repeat as necessary. With marinol, you need to wait for it to take effect.


--------------------
Acid doesn't give you truths; it builds machines that push the envelope of perception. Whatever revelations came to me then have dissolved like skywriting. All I really know is that those few years saddled me with a faith in the redemptive potential of the imagination which, however flat, stale and unprofitable the world seems to me now, I cannot for the life of me shake.

-Erik Davis

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Invisiblefastfred
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Re: Weak Marijuana Works as Well as High-Dose THC Pills [Re: OneMoreRobot3021]
    #7141380 - 07/07/07 08:34 AM (16 years, 7 months ago)

Anyone know if you can crack open a marinol pill and smoke it?

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OfflinechemiKalz
u r tripp0r?
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Registered: 09/08/05
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Re: Weak Marijuana Works as Well as High-Dose THC Pills [Re: fastfred]
    #7143444 - 07/07/07 08:03 PM (16 years, 7 months ago)

Quote:

fastfred said:
Anyone know if you can crack open a marinol pill and smoke it?




:cop:


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Invisiblejeetered
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Re: Weak Marijuana Works as Well as High-Dose THC Pills [Re: veggie]
    #7145504 - 07/08/07 08:08 AM (16 years, 7 months ago)

when i had a script for the tens last year, i attempted soaking a cigarette in the oils, then try to smoke it, it not only tasted like complete ass, it did nothing.

BUT, taking two or three, then letting them sit in for about an hour, and smoking some hits of KB made me unable to maintain balance, and I ate 80 dollars worth of groceries in 45 minutes. (maybe longer, i was stoned)

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