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OfflineImperialCactus
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Registered: 12/23/05
Posts: 532
Last seen: 11 years, 1 month
5-HTP and SSNRI interactions
    #6350004 - 12/09/06 02:46 AM (17 years, 2 months ago)

So, based on everything i've heard and read about 5-HTP, it sounded like something worth trying. I had never bought any though, until yesterday which was sort of an impulse buy. Anyways, i'm wondering if taking this along with an SSNRI or SSRI would be a bad idea.

I know this isn't an SSRI, but it's very possible that i will be put back on one and i'm not sure what class Lamictal falls under... anti-convulsant i guess. If the Lamictal doesn't help then i will be put on Cymbalta, which is where the SSNRI part comes from. So i guess this is a two part question really. Oh, and i should probably mention that i'm taking all this stuff for depression.

The only thing i can think of as far as Lamictal goes is that if i were to take 5-HTP and it helped, i wouldn't know what would be causing it. This is only the 7th day of taking Lamictal, and still only 25mg's as well. I don't think the two should conflict since i'm fairly sure it doesn't affect Serotonin at all, although i'm having a hard time finding something to specifically confirm that.

As for the Cymbalta, that does work on Serotonin which makes me wonder if combining the two would be a bad idea. If so then i should probably return the 5-HTP, since i didn't think of this at first and it was expensive as fuck... i'd keep it around for the occasional Ecstasy use but if i'm put back on an SSRI then that would be pointless.


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Invisibleredtailedhawk
Explorer of the Mystery
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Registered: 11/24/04
Posts: 559
Loc: The Old Continent
Re: 5-HTP and SSNRI interactions [Re: ImperialCactus]
    #6350269 - 12/09/06 07:42 AM (17 years, 2 months ago)

Mixing the two could be very dangerous. Avoid at all cost. If you want to know more Google HTP+SSNRI.


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"Who are you who live in all these many forms? You're death that captures all. You too are the source of all that's gonna be born. You're glory, mercy, peace, truth. You give calm a spirit, understanding, courage, the contented heart."


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Invisibledblaney
Human Being

Registered: 10/03/04
Posts: 7,894
Loc: Here & Now
Re: 5-HTP and SSNRI interactions [Re: ImperialCactus]
    #6351305 - 12/09/06 02:57 PM (17 years, 2 months ago)

Perhaps the more relevant question is why do you think you shouldn't be depressed?


--------------------
"What is in us that turns a deaf ear to the cries of human suffering?"

"Belief is a beautiful armor
But makes for the heaviest sword"
- John Mayer

Making the noise "penicillin" is no substitute for actually taking penicillin.

"This country, with its institutions, belongs to the people who inhabit it. Whenever they shall grow weary of the existing government, they can exercise their constitutional right of amending it, or their revolutionary right to dismember or overthrow it." -Abraham Lincoln


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Offlinebrowndustin
dustybuddy

Registered: 10/03/03
Posts: 2,957
Last seen: 9 years, 9 months
Re: 5-HTP and SSNRI interactions [Re: dblaney]
    #6351636 - 12/09/06 04:29 PM (17 years, 2 months ago)

BE CAREFUL!


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When the stress burns my brain it's like acid raindrops
maryjane is the only thing that makes the pain stop


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Invisibledblaney
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Registered: 10/03/04
Posts: 7,894
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Re: 5-HTP and SSNRI interactions [Re: browndustin]
    #6351653 - 12/09/06 04:33 PM (17 years, 2 months ago)

Careful about what? For a great many people who are 'depressed', they think that being depressed is somehow bad and wrong. They think that they should be happy. Yet this feeling that their current state is somehow not right and they should be otherwise is very often a significant cause of their distress and unhappiness.

Many times, depression is a wake up call, telling you that something needs work. Maybe it's your lifestyle, maybe your attitude, maybe your beliefs. But simply dismissing depression as a state of mind that for whatever reason SHOULD NOT and sometimes MUST NOT be around is not only futile, but usually counter-productive!


--------------------
"What is in us that turns a deaf ear to the cries of human suffering?"

"Belief is a beautiful armor
But makes for the heaviest sword"
- John Mayer

Making the noise "penicillin" is no substitute for actually taking penicillin.

"This country, with its institutions, belongs to the people who inhabit it. Whenever they shall grow weary of the existing government, they can exercise their constitutional right of amending it, or their revolutionary right to dismember or overthrow it." -Abraham Lincoln


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OfflineImperialCactus
Stranger

Registered: 12/23/05
Posts: 532
Last seen: 11 years, 1 month
Re: 5-HTP and SSNRI interactions [Re: dblaney]
    #6352159 - 12/09/06 07:44 PM (17 years, 2 months ago)

I'm not really sure how to answer that... i used to get very suicidal at times, which is why i decided that things weren't working and that i might as well try seeing someone about that. Recently though things have been going a little better, and i still have my problems but am generally not as suicidal at least. I won't bother you with all the reasons why i think i'm depressed, unless someone actually wanted to hear about all that for some reason.

I guess serotonin syndrome is one possibility, didn't think of that at first either... although i don't know just how likely or probable that would be. I still don't know if it would be a bad idea with the Lamictal, but i guess i'll just wait until i'm not taking any of this crap anymore.


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Offlinebrowndustin
dustybuddy

Registered: 10/03/03
Posts: 2,957
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Re: 5-HTP and SSNRI interactions [Re: dblaney]
    #6353116 - 12/10/06 02:30 AM (17 years, 2 months ago)

Quote:

dblaney said:
Careful about what? For a great many people who are 'depressed', they think that being depressed is somehow bad and wrong. They think that they should be happy. Yet this feeling that their current state is somehow not right and they should be otherwise is very often a significant cause of their distress and unhappiness.

Many times, depression is a wake up call, telling you that something needs work. Maybe it's your lifestyle, maybe your attitude, maybe your beliefs. But simply dismissing depression as a state of mind that for whatever reason SHOULD NOT and sometimes MUST NOT be around is not only futile, but usually counter-productive!




I'm just stating that a drug isn't always the magic puzzle peice that's going to make everything better. Depression should definitely be tackled from a multitude of angles. Just messing with seritonen is something that scares me.

I think a lot of the anecdotal feedback is just placebo. I thought that SSRI's fixed my problems but when I realized that I was more of a zombie and so close to suicide, a part of me decided that I should stop. Not before I got seritonen syndrom though.. blah. It's late.


--------------------
When the stress burns my brain it's like acid raindrops
maryjane is the only thing that makes the pain stop


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Invisibledblaney
Human Being

Registered: 10/03/04
Posts: 7,894
Loc: Here & Now
Re: 5-HTP and SSNRI interactions [Re: browndustin]
    #6353183 - 12/10/06 03:42 AM (17 years, 2 months ago)

:smile:

Sounds like we are in complete agreement!


--------------------
"What is in us that turns a deaf ear to the cries of human suffering?"

"Belief is a beautiful armor
But makes for the heaviest sword"
- John Mayer

Making the noise "penicillin" is no substitute for actually taking penicillin.

"This country, with its institutions, belongs to the people who inhabit it. Whenever they shall grow weary of the existing government, they can exercise their constitutional right of amending it, or their revolutionary right to dismember or overthrow it." -Abraham Lincoln


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OfflineImperialCactus
Stranger

Registered: 12/23/05
Posts: 532
Last seen: 11 years, 1 month
Re: 5-HTP and SSNRI interactions [Re: browndustin]
    #6354118 - 12/10/06 01:27 PM (17 years, 2 months ago)

Thanks for the advice everyone, i'm going to return the 5-HTP and continue to work with my psychiatrist a bit longer since he really does seem to know what he's doing and i really haven't given him enough of a chance yet. Of course i'll continue to work on other things and aspects of my life not involving drugs as well, i'm just getting kinda short on ideas there, which is why i decided to try all this in the first place.

I am starting to realize that a lot of this has been a placebo effect though. It seems that when i first start taking something, i feel better... however it's unlikely any of these drugs would have that effect so soon, and then eventually i do realize that nothing has changed and i'm right back where i started pretty much. And for the record i don't like the idea of screwing with serotonin levels either, but maybe i really do have a physical, medical problem that needs to be addressed. So i don't know, i realize no drug is going to fix all my problems but i am hoping that it can help... i guess i'll see. Thanks again for the advice.


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OfflineschmutzenS
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Registered: 12/03/02
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Re: 5-HTP and SSNRI interactions [Re: ImperialCactus]
    #6366807 - 12/13/06 04:30 PM (17 years, 2 months ago)

Cymbalta is nasty, nasty stuff. It's habit-forming and has been shown to increase suicidal thoughts and tendencies. It's like really dirty speed, I tried it for three days and didn't sleep the entire time. Your dr. will most likely say that since 5-HTP is not recognized by the FDA to treat a disease, then it's worthless. I say try the 5-HTP before trying any antidepressants. The Natrol brand 5-HTP is a lot cheaper than the health food variety.


--------------------


"Blow up your TV, throw away your paper.  Go to the country, build you a home."


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OfflineImperialCactus
Stranger

Registered: 12/23/05
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Last seen: 11 years, 1 month
Re: 5-HTP and SSNRI interactions [Re: schmutzen]
    #6368905 - 12/14/06 01:44 AM (17 years, 2 months ago)

Hmm, well thanks for that. I have a feeling my psychiatrist would say something along the lines of there are better, more effective things to try... but i doubt he would say that it's completely worthless. Maybe it really wouldn't help me, i don't know. I do have the Natrol brand, but i think my mistake was in getting it from GNC, since i paid $15 for 30 100mg pills, so i'm definitely taking those back now that i know they can be much cheaper.

I don't really like the sound of Cymbalta so far, but i will give it a try at least, if that's what he really thinks i should do. I don't see him for another week or two anyways, don't remember the exact date. If it's anything like Paxil i don't think i'll be taking it for very long though, since the side effects from that really did suck, and even if it did help i'm not sure that it would be worth it. Hopefully Cymbalta won't be as bad for me.


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OfflineschmutzenS
King of the side-pins
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Registered: 12/03/02
Posts: 15,387
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Re: 5-HTP and SSNRI interactions [Re: ImperialCactus]
    #6369742 - 12/14/06 10:06 AM (17 years, 2 months ago)

Quote:

since i paid $15 for 30 100mg pills




I think that's about what it runs for, the cymbalta OTOH is definately more than that even with really good insurance. I really encourage you to read as much as possible about cymbalta before trying it. http://www.askapatient.com/viewrating.asp?drug=21427&name=CYMBALTA This is a very unbiased page, depending on your condition it just may help you, and God Bless if it does.

Just beaware there were deaths during the testing of this medicene; if you think it is increasing your thoughts of suicide - i think it would be better to stop taking it then wait it out until you see your dr. again.

Here's the FDA study, 18-64 year olds are at increased risk: http://www.keprtv.com/news/health/4842866.html


--------------------


"Blow up your TV, throw away your paper.  Go to the country, build you a home."


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