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Re: Syrian Rue and mushrooms [Re: GenesisCorrupted]
    #28500229 -

GenesisCorrupted said:
I have this for the rest of the month. I’ve already been on the Dmt diet for like four months. So it won’t cause any interactions. But now that I know this. I will request an RIMA for the refill.
Then I get to fully enjoy a lot of things that have been falsely advertised as toxic poison to me.
I gave you a user review by the way. You’re like the most reliable source of information on these topics.
That’s how badly Google understands this topic.😂



Well i've done a lot of research and experimentation lol, and yet, some people still tell me i'm wrong sometimes lol. I mean idk everything, but i do know a good bit lol.

But yeah see if you can get a RIMA like Moclobemide, though it's not available here in the US it is available in Canada and Australia, but one can try to find it via an online pharmacy (which is where i had gotten my Moclobemide), or you can see if a psychiatrist will prescribe it and they can either maybe order it from Canada or overseas or you can send the prescription to an online pharmacy in Canada or overseas and have it shipped here, from what i've read.


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Re: Syrian Rue and mushrooms [Re: Sabnock] * 1
    #28500232 -

It would be worth it. Also, the psychiatrist I got is pretty cool. Otherwise he wouldn’t of even prescribed me an MAO. So I’m sure they would be willing to work with me in getting a medication that works better.

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Re: Syrian Rue and mushrooms [Re: GenesisCorrupted]
    #28500295 -

Triptamines and ketamine are safe but just don't take phenyethylamines even with reversible maois, because some phenylethylamines has some serotonin uptake inhibition activity. I actually try 150 mg moclo many times with with mdma, mescaline but dosage is really important (I prefer to not go over 150 mg and small amount of pea) but it may be dangerous for some people. Also I feel opoid mu receptor activity from peganum harmala if I go over 4 grams, i could not find literature about it, but i feel it.

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Re: Syrian Rue and mushrooms [Re: taskamil] * 1
    #28500310 -

taskamil said:
Triptamines and ketamine are safe but just don't take phenyethylamines even with reversible maois, because some phenylethylamines has some serotonin uptake inhibition activity. I actually try 150 mg moclo many times with with mdma, mescaline but dosage is really important (I prefer to not go over 150 mg and small amount of pea) but it may be dangerous for some people. Also I feel opoid mu receptor activity from peganum harmala if I go over 4 grams, i could not find literature about it, but i feel it.



Yeah Rue definitely interacts with the Opioid system, i can feel it too, to a degree, though it seems to be safer i'm pretty sure compared to actual Opiates, because i've taken Rue very regularly (daily for long periods of time) and let the Harmala reverse tolerance build up and so the dosage just gets stronger and stronger, at least for the Harmalas, while the background compounds are Rue-dosage dependent, the Harmalas are reverse tolerance-dependent, but if you take either high/heavy dosages of Harmalas, or about 4 grams or higher of Rue, there's definite pain relief and body relaxation there, even the next day or so, i'm pretty sure it's Harmaline-related because Harmine doesn't seem to have those properties that i've been able to tell and i've noticed it with Harmala extract which tells me it's coming from the Harmaline most likely, though some of Rue's other background compounds may well contribute as well. Either way, it doesn't seem to be unsafe or addictive or anything like actual Opioids so it likely has some sort of modulatory effect like positive allosteric modulation or indirect activation through some other mechanism. Plus if it had true full on Opioidergic properties it would cause some sort of withdrawal you would think, yet i've noticed no withdrawal at all from Rue, i've taken it daily in heavy dosages for years, and just stop taking it and over a few weeks to a couple months i slowly just return to baseline and any residual effects are then gone.

There's some studies that mention it interacts with the Opioid system, here's one - "These result showed that the alkaloid extract of Pgh contains active analgesic principles acting both centrally and peripherally. Furthermore, this antinociceptive effect has been avoided by naloxone at a dose of 1mg/kg in the first phase of formalin and hot plate tests indicating that this extract act partly through an opioid-mediated mechanism. In conclusion, the alkaloid extract of Peganum harmala seems to have both central and peripheral antinociceptive activities which may be mediated by opioid receptors." - https://pubmed.ncbi.nlm.nih.gov/18054186/

As for MDMA, it's definitely not advised to take that with Harmalas or Moclobemide, although it may well be doable so long as the dosage is controlled for. I've only had MDMA once at approx 100mgs, i had been taking my usual heavy dosages of Harmalas/Rue, and merely skipped taking it a day and took the MDMA, and the next day went back to the Rue, so i had Rue the day before and the day after the MDMA and had been dosing Harmalas/Rue on the regular, and yet didn't seem to have any issue, although the MDMA was rather strong and made my head felt like it was disappearing while having diarrhea, i didn't even really get anything good from the MDMA, i just felt really calm, but at the same time i do believe i was already low in Serotonin and had been for a long time in my life apparently, so idk maybe that's why i didn't get much of a good effect from the MDMA, either that or me taking the Rue around the same time did something but i think i was just low in Serotonin, which MDMA probably even made that worse lol. Granted i didn't have any negative interactions/reactions to the MDMA, it just felt strong and wasn't particularly fun or enjoyable and pleasurable.


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Re: Syrian Rue and mushrooms [Re: Sabnock] * 1
    #28500349 -

Yes I found new literature about harmaline efecting ventral tegmental area glutamatergic system and potenciates mu activity. So because of no direct agonist effect of mu receptors, there is no risk of withdrawal or any other opoid related side effects, probably it potenciates just internal opoid system. Actually because I don't like metylphenidate excess energy effects, harsh comedown and also become harder to find, I also started using rue 0.5 gram daily for one month for my adhd and makes me feel good and less distractive, more productive and good for general health. I am considering to go to 1 gram daily.

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Re: Syrian Rue and mushrooms [Re: Sabnock] * 1
    #28500350 -

Sabnock said:
taskamil said:
As for MDMA, it's definitely not advised to take that with Harmalas or Moclobemide, although it may well be doable .



I have been told and will be doing more research.

Mdma does both dangerous activites.
Ups heart rate. Hypertensive crises
And produces a lot of serotonin.
Serotonin syndrom.

Edited by GenesisCorrupted (10/11/23 04:16 PM)

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Re: Syrian Rue and mushrooms [Re: GenesisCorrupted] * 2
    #28500353 -

GenesisCorrupted said:
Sabnock said:
taskamil said:
As for MDMA, it's definitely not advised to take that with Harmalas or Moclobemide, although it may well be doable .



I have been told and will be doing more research.

Mdma does both dangerous activites.
Ups heart rate. Hypertensive crises
And produces a lot of serotonin.
Serotonin syndrom.



Yes it is dangerous but it can be doable at right dosages. There are death reports combining maoi with mdma just dont do if you are not sure about dosage or not sure about your substance.

You can read this article it is old but information there is valueable.

https://maps.org/news-letters/v06n3/06332ott.html

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Re: Syrian Rue and mushrooms [Re: Sabnock] * 1
    #28501157 -

I definitely feel the pain relief from Syrian Rue as well. I’ve thought to myself many times how it feels comparable to a small amount of opium, but with more positivity and energy.

Really cool to hear that it affects other people this way as well.

Northener introduced me to harmalas and they’ve done me a world of good since I started taking them.

One other interesting thing that I’ve noticed recently is that when I chew fresh seeds they seem to be a lot more stimulating than a harmala extract. I’m not sure what causes this so if anyone could enlighten me that would be great! Harmala extract still has all of the pain relieving and antidepressant qualities, but the fresh seeds have an extra energy boost as well.


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"God is an intelligible sphere, whose center is everywhere and whose circumference is nowhere."

Llamando la Mareacion

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Re: Syrian Rue and mushrooms [Re: Bardy] * 1
    #28501347 -

Good timing on this weird thread resurrection, I bought some powdered rue and plan on taking 2-3g rue + 2g liberty caps with it tomorrow or Saturday.
I've been reading conflicting stories about nausea caused by unextracted rue. Those with a lot of experience with it, how bad is it actually? I'll take them as separate teas 20-60 mins apart and I'll have some fresh ginger (helps with nausea apparently?) and a bucket for emotional support.


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Re: Syrian Rue and mushrooms [Re: Turvenuija] * 1
    #28501435 -

I definitely puked on rue + extracted dmt.  Experiences with harmine extracts + ACRB tea were much more gentle on my stomach.

Making tea from the liberty caps, rather than ingesting the mushrooms themselves, will help too.


--------------------
And if I only could
I'd make a deal with God
And I'd get him to swap our places
I'd be running up that road
Be running up that hill
With no problems

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Re: Syrian Rue and mushrooms [Re: tree frog]
    #28501498 -

Yeh I have a feeling I'm going to hurl, I get some nausea from shroom tea alone but that's fine, puking has never ruined trips for me. Get it over with, get the taste out and carry on. I'll look into extracting for the future, it doesn't look hard at all just time consuming.


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Re: Syrian Rue and mushrooms [Re: Turvenuija]
    #28501552 -

Turvenuija said:
Good timing on this weird thread resurrection, I bought some powdered rue and plan on taking 2-3g rue + 2g liberty caps with it tomorrow or Saturday.
I've been reading conflicting stories about nausea caused by unextracted rue. Those with a lot of experience with it, how bad is it actually? I'll take them as separate teas 20-60 mins apart and I'll have some fresh ginger (helps with nausea apparently?) and a bucket for emotional support.



This is based off of my personal experience.
At first when your body has nothing to fear, Syrian Rue is fine.
In fact, it made me hungry multiple times.
But it does produce nausea I know for a fact.
Because physiologically I started getting more and more nauseous just by the smell of it.
Those last couple caps I had of Syrain Rue...
The smell of them was enough to turn my stomach and make me nauseous just being near the box that I kept them in.
That’s how powerfully the nausea works on you. The smell alone is enough.

I use pure harmalla extract or pills.
I’m so happy that I’m not using the actual Syrian rue pill capsules anymore.
Just keep marijuana nearby. You’re gonna need it.

I implore you to not make tea!!!
Get a scale it doesn’t have to be wildly accurate.
Measure out how much 3 Gelcaps Weigh on their own. Get the triple 000
Subtract that from the weight of your measured out Syrian rue seed. So that you’re right around 2 1/2 to 3 g.
It’ll take about 30 minutes for you to absorb the contents of those seeds.
Even with nothing being tasted at all.
You will still feel a little bit nauseous.
It won’t be bad enough to even need medicine until you try to put anything else on top of it that also produces nausea. Then you will have wild crazy ass nausea.
Here’s my reference material.
Mushrooms and Dmt both produce a similar amount of nausea when combined with this chem.


You do not want any of the flavor in your mouth at all…
Super duper better experience.
For comparison.
Imagine you left a tea bag of Earl Grey in a mug for three days….
Then somebody made you drink it.
Then, when you finally finish swallowing it. They put a gun up to your head and said you needed to suck on the teabag for a couple minutes.
That’s the aftertaste…
For all that is good in the world. For god sake. Just get some empty pill caps. Even empty some if you have some around the house that you’re not gonna use. Because the nausea that you have will be pretty significant. I didn’t realize how nauseous I was until the fourth time I tried to do it, and I got nauseous before I even finished picking up the Rue pills.
https://www.shroomery.org/forums/showflat.php/Number/28447856
This is my nausea free recipe
I can’t even imagine a worst way to use Syrian Rue.

Edited by GenesisCorrupted (10/12/23 12:45 PM)

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Re: Syrian Rue and mushrooms [Re: GenesisCorrupted]
    #28501596 -

GenesisCorrupted said:
Turvenuija said:
Good timing on this weird thread resurrection, I bought some powdered rue and plan on taking 2-3g rue + 2g liberty caps with it tomorrow or Saturday.
I've been reading conflicting stories about nausea caused by unextracted rue. Those with a lot of experience with it, how bad is it actually? I'll take them as separate teas 20-60 mins apart and I'll have some fresh ginger (helps with nausea apparently?) and a bucket for emotional support.



This is based off of my personal experience.
At first when your body has nothing to fear, Syrian Rue is fine.
In fact, it made me hungry multiple times.
But it does produce nausea I know for a fact.
Because physiologically I started getting more and more nauseous just by the smell of it.
Those last couple caps I had of Syrain Rue...
The smell of them was enough to turn my stomach and make me nauseous just being near the box that I kept them in.
That’s how powerfully the nausea works on you. The smell alone is enough to make your body start getting nauseous again.

I use pure harmalla extract or pills.
I’m so happy that I’m not using the actual Syrian rue pill capsule anymore.
Just keep marijuana nearby. You’re gonna need it.



Oh boy, i know this all too well lol. Same thing happened to me, just the smell of the Rue, the sight of the Rue powder, instantly would make me queasy and wanna gag and throw up lol. It can be rather deterring but i know the magick that Rue holds so i look past the nausea and vomiting and all that, but it is quite the pungent seed.

With that said, there are two ways that i go about dealing with the nausea/vomiting, i either take the Rue/Harmalas regularly (usually daily, at night, but a few times a week seems to also be fine ime) which will build up the reverse tolerance and with that the side-effects including the nausea/vomiting/diarrhea will go away and the bodyload will clean up and the motor impairment goes away and then even heavy dosages of Harmalas will feel pretty clean and are functional and won't cause anymore nausea/vomiting.

Or i use Limonene, which is a compound found in a wide variety of plants and essential oils, and is a major component of Lemon essential oil which people have touted as an anti-nausea remedy though they attributed it to Beta-Pinene, it's actually the Limonene, and so i recommend trying pure Limonene, get the pure oil form and not the supplement form because the supplement form is too high of a dosage at 500mgs to 1 gram, whereas you want more along the lines of 6 to 10 drops, 8 to 10 drops particularly seemed to help for me but 6 drops may even be enough, which would equate to about 108 to 180mgs, and so you just put the Limonene drops into a capsule using a dropper, and take it at the same time as the Rue/Harmalas, and it will remove most if not all of the nausea/vomiting ime, and i've gotten good feedback so far about it and that it works for others, so it might be something worth trying. The Limonene also seems to clean up some of the bodyload to a degree i think, it feels nice though ime.

As for things like Ginger or Zofran or Peppermint, they all act as Serotonin 3 receptor antagonists, which can be useful for nausea/vomiting, and some folks claim that it helps with the Aya or mushrooms or what not, but ime anytime i've tried Ginger or Zofran or Peppermint with Aya or even the Rue/Harmalas, idk, i find that it really doesn't help me with the nausea/vomiting but it also alters things in a really weird way that i don't particularly like or get benefit from. Plus with Peppermint, there's also other properties it has, including GABA-A receptor activity which on one hand may be useful but on the other hand i feel like it dulls things down, which is contrary to what Lemon Balm does for me through it's GABAergic properties which doesn't seem to dull things down but still relaxes things and smooths things out. So as far as GABAergic properties go, Lemon Balm is great, but Peppermint not so much, ime.

And yes, Cannabis is imo/ime definitely worth having around for gut discomfort and nausea, it's a great ally.

But yeah Rue seed powder encapsulated can be a bit more rough on the gut, at least at first, but if you build up the reverse tolerance and do away with the side-effects, and get your body used to it, and plus Rue/Harmalas have anti-microbial properties and so it'll interact with the gut microbiome which needs to get used to it, and then things feel better, even with the seed powder. But extracts are nice too, i much prefer the Rue seed itself over the extracts though because the seed itself has a lot more going on and feels more natural and magickal, whereas the extract feels more isolated and medicinal, which isn't an issue for me as i can certainly use that, but as far as extracts go i prefer homemade full spectrum freebased extract, which apparently you can't buy online that i've seen, some vendors list their Harmala extracts as full spectrum but they're not truly full spectrum, they're manske'd extracts which is basically just a pure Harmaline/Harmine mix, but the true full spectrum extract also has some other alkaloid from the Rue, but it doesn't get everything, it just adds a few more compounds to the mix and makes it feel better and closer to but lighter than the seed, so i recommend making your own full spectrum Rue extract and trying that out and comparing how it feels to the manske'd Harmala extract.


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Re: Syrian Rue and mushrooms [Re: Turvenuija] * 1
    #28501608 -

Turvenuija said:
Good timing on this weird thread resurrection, I bought some powdered rue and plan on taking 2-3g rue + 2g liberty caps with it tomorrow or Saturday.
I've been reading conflicting stories about nausea caused by unextracted rue. Those with a lot of experience with it, how bad is it actually? I'll take them as separate teas 20-60 mins apart and I'll have some fresh ginger (helps with nausea apparently?) and a bucket for emotional support.



Encapsulate the powdered Rue seed, tea is horrid lol. Encapsulate the powder, take the Rue capsules, then 30 minutes to an hour later drink the mushroom tea (i recommend an hour which seems to do good for me personally).

The nausea/vomiting from Rue can be pretty strong for sure, but it's really not that bad if you don't go too high on the dosage. Which i recommend 2.5 to 3 to 3.5 grams of Rue, but 2.5 grams at least, 2 grams is a bit low though it can work but 2.5 grams of Rue is better. And 2 grams of mushrooms is fine, though for the "full shebang" i do recommend trying 2.5 to 3.5 grams, which with proper potentiation would be near about 5 to 7 grams equivalent, ime, but again potency can vary so 2 grams can be a nice place to start i've just found 2 grams of mushrooms ime to be a little light.

But yeah the nausea/vomiting can also most certainly happen with Harmala extracts too, however the extracts are less likely to cause nausea or stomach discomfort, but with a high enough dosage can certainly still make you vomit lol, which is more of an easier purge compared to with the Rue seed but none the less, the Rue seed itself ime is where the real magick is, i've had great experiences/effects/benefits using extracts but i always end up going back to the seed itself as it seems to give me effects i don't get when using extracts.


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Re: Syrian Rue and mushrooms [Re: Bardy]
    #28501610 -

Bardy said:
I definitely feel the pain relief from Syrian Rue as well. I’ve thought to myself many times how it feels comparable to a small amount of opium, but with more positivity and energy.

Really cool to hear that it affects other people this way as well.

Northener introduced me to harmalas and they’ve done me a world of good since I started taking them.

One other interesting thing that I’ve noticed recently is that when I chew fresh seeds they seem to be a lot more stimulating than a harmala extract. I’m not sure what causes this so if anyone could enlighten me that would be great! Harmala extract still has all of the pain relieving and antidepressant qualities, but the fresh seeds have an extra energy boost as well.



I get the stimulation too, honestly to me it feels a bit more like it comes from the Harmaline, even though Harmaline can have a bit more sedative properties and Harmine is said to be a bit more stimulating, so it could be the Harmine but at the same time using pure Harmine or light roast Rue or Caapi doesn't seem to give me the stimulant effect i notice, which imo likely comes from Harmaline. Harmaline does have some actions as a GABA-A inverse agonist (which i've often used 3 to 4.5 grams of dried Lemon Balm leaf tea to counteract) which may perhaps lead to some stimulation, it also inhibits COMT which is involved in the metabolism of Dopamine and Noradrenaline but idk if that would contribute or not, i'm sure it has some other properties though that may be involved.


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Re: Syrian Rue and mushrooms [Re: Sabnock] * 1
    #28501620 -

I love when you weigh in on this topic.
I gotta get some of that limonene.
I’m very interested in trying it to ease the come up.
I find that the Ayahusca doesn’t produce an open eye visual for me unless I go into the very heavy dosage range. Is it just set & setting holding me back or am I not doing a big enough dose to get to where I’m trying to go to?
I’ll end up getting that thing where everything looks normal. Until you look at your phone. Then words try and get like Drifty…
Like every other letter, in a word, will start sliding down the screen as if it’s melting a little bit. Which is very cool. But it seems like my cell phone is one of the only things that even produces this.
Another time I was trying to watch knives out. Everything was completely normal until Daniel Craig turned once. Then there was a third eye behind his ear!

These are not the visuals that you are looking for!

Edited by GenesisCorrupted (10/12/23 12:59 PM)

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Re: Syrian Rue and mushrooms [Re: Sabnock]
    #28501624 -

Also, one fun fact that y'all might make use of, is that you can use either pure Harmine or properly light roasted Rue seed (which will break down the Harmaline content while sparing the Harmine content and some of the background compounds), and either take that for a bit, or mix it with the raw Rue or the Harmala/Rue extracts, and it will boost the Harmine concentration and raise Harmine above Harmaline so that Harmine is dominant and Harmaline is secondary, seems to feel better that way ime, and plus that's one reason why some folks don't like Rue because it's dominant in Harmaline, but if you raise the Harmine concentration, it feels better.

And, if you take the same dosages, like say you take 2 to 4 grams of properly light roasted Rue for the Harmine content, and you let the reverse tolerance to Harmine build up some, you can then switch to using the same dosage of raw Rue instead of the light roast (or pure Harmine extract), and the Harmine dosage will stay at the same level and will continue to be dominant even with Harmaline's reverse tolerance building up. This way, you can alter the ratio of Harmine to Harmaline. And you can mix light roast and raw Rue's (or add pure Harmine to the raw Rue) and use a little bit of raw Rue and then make up for the rest of it with light roast or pure Harmine.


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Re: Syrian Rue and mushrooms [Re: Sabnock]
    #28501627 -

Since I’ve been trying to experience EyeCandy
I wanted to use the harmaline because I heard it was harder hitting.
But if it’s body load and not visual. Then I’m going to get harmine next time. I had a choice.
I chose to get harmaline powder. It only has 2% harmine in it.
I could’ve gotten the exact opposite. 97% harmine. 2% harmaline.

They also offer mix. Where they offer some thing that they claim to be 50-50 split.
The people are youse are very good. They make whatever you really one of the three options. I just thought that harmaline was the way to go.

Edited by GenesisCorrupted (10/12/23 01:02 PM)

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Re: Syrian Rue and mushrooms [Re: Sabnock] * 1
    #28501629 -

I knew that you could roast them to release some of the chemicals and destroy some of the unpleasant compounds. I learned that from watching some dudes trying to make Yopo. But I don’t want to destroy any of my compounds. I’m just gonna get a better mix next time.

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Re: Syrian Rue and mushrooms [Re: GenesisCorrupted]
    #28501631 -

GenesisCorrupted said:
I love when you weigh in on this topic.
I gotta get some of that limonene.
I’m very interested in trying it to ease the come up.
I find that the Ayahusca doesn’t produce an open eye visual for me unless I go into the very heavy dosage range. Is it just set & setting holding me back or am I not doing a big enough dose to get to where I’m trying to go to?
I’ll end up getting that thing where everything looks normal. Until you look at your phone. Then words try and get like Drifty…
Like every other letter, in a word, will start sliding down the screen as if it’s melting a little bit. Which is very cool. But it seems like my cell phone is one of the only things that even produces this.
Another time I was trying to watch knives out. Everything was completely normal until Daniel Craig turned once. Then there was a third eye behind his ear!

These are not the visuals that you are looking for!




Yeah this stuff for me isn't particularly visual, lots of folks even with traditional Aya seem to not get much in the way of visuals, although some other folks get very obvious visuals and then act like visuals are supposed to be there when really this kind of medicine doesn't seem to be particularly visual at least for me, i get pretty much everything else but the visuals lol.

As far as the visuals go, it's mainly Harmala visuals like open eyed tracers and such, maybe some "lightness" where it feels like there's a mild light kinda lighting up the darkness in a way, idk, and there's some mental imagery that comes through to me sometimes that is mostly just random people doing random things, scenes that flash by rather quickly, almost like if you took snippets from a bunch of random movies and edited them together where it's just one quick glimpse scene after the other, it's kinda like that, i just see people, faces, them doing random things, idk what it is. Sometimes i'll also see like jungle imagery. But i really don't get much in the way of mental imagery/closed eyed visuals, they're fairly mild no matter the dosages of Harmalas/Rue or DMT, for me anyways.

Also ime there seem to be this thing i've noticed where at certain dosages of the Harmalas, things tend to be a bit more visual but beyond that certain dosage range it becomes less visual and more physical which definitely has it's benefits that i don't get from dosages below that. So there may be something to do with the dosage range of Harmalas playing into the visuals. Also i think extra Harmine makes things a bit more visual as well.

Another thought i've had is that perhaps if someone doesn't get visuals, maybe they're low in certain vitamins, particularly the B vitamins, ime. I've begun to supplement with B vitamins the last few months because i apparently wasn't getting enough from my diet, and i have noticed some visual activity picking up recently, so i'm not sure if that's because of the raised Harmine concentration or if it's because of the vitamins, but i do think in any case, B vitamins are really important and you want to make sure you're getting those. Magnesium too, as Harmalas seem to use up or deplete Magnesium, which for me causes cramping and heart palpitations and then i know i'm low and have to supplement.


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Edited by Sabnock (10/12/23 01:25 PM)

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