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OfflineJfisher
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Marijuana May Cause Pregnancies To Fail
    #5922769 - 08/01/06 06:40 PM (17 years, 9 months ago)

Marijuana may cause pregnancies to fail

* 22:00 01 August 2006
* NewScientist.com news service
* Michael Day


Smoking marijuana at the time of conception could cause pregnancies to fail, new research in mice suggests. The same problem may occur as a result of taking the slimming drug, rimonabant.

The warnings come from embryologists who have discovered key factors that govern an embryo’s chances of successful implantation. After fertilisation in humans and mice, the egg faces a perilous path from the place of conception in the fallopian tube down into the womb.

The team from Vanderbilt University Medical Centre, Tennessee, US, has shown that precisely the right levels of a chemical called anandamide are required for this passage to be completed safely. Increasing or decreasing the amount of anandamide drastically harms mouse embryos’ chances of normal implantation and survival.

Their research reveals that anandamide levels in the fallopian tubes are governed by two enzymes: one called NAPE-PLD increases levels of anandamide, while NAAH reduces them.
Cannabinoid receptor

Significantly, the team also found that exposing the mice to certain drugs disrupted this delicate balance, thereby impeding an embryo's ability to pass into the womb. One such substance is tetrahydrocannabinol (THC), the major psychoactive component of marijuana.

Like anandamide, it binds to the cannabinoid receptor CB1, thereby displacing anandamide and boosting levels of the chemical present in the oviduct.

The discovery poses worrying questions about the ability of marijuana, the most widely used illegal drug among women of reproductive age, to harm pregnancy, says the lead researcher, Sudhansu Dey.

“This is worrying because embryo retention is a significant cause of ectopic pregnancy in women,” he says. He also notes that the incidence of such abnormal and dangerous pregnancies has risen sharply in the past decade.
Slimming pills

Another expert in reproductive biology, Herbert Schuel at the State University of New York in Buffalo, US, points out that some new medicines also interacted with CB1 receptors and therefore had the potential to disrupt amandine levels and embryo development. One such drug, the slimming pill rimonabant – sold as Acomplia – is already licensed in the UK.

“Given the results of the study, we need to be very sure that rimonabant doesn’t have unwanted effects on women of reproductive age," Schuel says. CB1 receptors are not just present in the brain but all over the body, including the reproductive system, he adds, "so we shouldn’t be surprised if it has unwanted effects".

A spokeswoman for rimonabant’s manufacturer, Sanofi-Aventis, said the company did not recommend the use of rimonabant during pregnancy and advised patients who are planning to become pregnant to seek immediate medical advice.

Journal reference: Journal of Clinical Investigation (vol 116, p 2087)


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OfflinePlaceholder
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Registered: 05/31/06
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Re: Marijuana May Cause Pregnancies To Fail [Re: Jfisher]
    #5922865 - 08/01/06 07:11 PM (17 years, 9 months ago)

I don't think marijuana use has dramatically gone up in the last 10 years, but prescription drug use sure as hell has.

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OfflineMicrocosmatrix
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Re: Marijuana May Cause Pregnancies To Fail [Re: Placeholder]
    #5923125 - 08/01/06 08:41 PM (17 years, 9 months ago)

I can't speak for everyone else but my marijuana use has gone up in the last 10 years. :wink:


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:orly:


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Offlinemakaveli8x8
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Re: Marijuana May Cause Pregnancies To Fail [Re: Microcosmatrix]
    #5923213 - 08/01/06 09:11 PM (17 years, 9 months ago)

micro you have some pretty eyes.


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We were sent to hell for eternity :hellfire: Ø:omgawesome:h®
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Over-population the root of all Evil-brings the Elites Closer to the gates.

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Offlinedownlowfunk
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Re: Marijuana May Cause Pregnancies To Fail [Re: makaveli8x8]
    #5923463 - 08/01/06 10:20 PM (17 years, 9 months ago)

Again more propaganda do not believe this at all. Marijuana has been proven to actualy help Pregnant women. This is complete b/s. No im not saying smoke a huge bong like Renee Bojee was doing but some marijuana will not hurt a pregnancy, and has been used through out history as a pain reliever during Labor. I dont know about you but I trust the herb, to sooth my womens pain more than I trust the Epideral.

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OfflineSchwip
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Re: Marijuana May Cause Pregnancies To Fail [Re: downlowfunk]
    #5923564 - 08/01/06 10:43 PM (17 years, 9 months ago)

Read the article again downlowfunk.

It states that THC causes complications around the time of conception.

Not 8 or 9 months into it.


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" If the sky were to suddenly open up there would be no law. There would be no rule. There would only be you and your memories... the choices you've made, and the people you've touched. If this world were to end there would only be you and him and no-one else. "

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OfflineCptnGarden
fuck this site
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Re: Marijuana May Cause Pregnancies To Fail [Re: Microcosmatrix]
    #5924162 - 08/02/06 01:31 AM (17 years, 9 months ago)

Quote:

Microcosmatrix said:
I can't speak for everyone else but my marijuana use has gone up in the last 10 years. :wink:




so has mine, and I bet everyones has, and I dont blame them. as soon as bush hit office I was tokin a gram+ a day. I bet the day he resigns ill be smoking much less, unless we get some dick like cheney. <--haha

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Invisiblefastfred
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Re: Marijuana May Cause Pregnancies To Fail [Re: CptnGarden]
    #5924691 - 08/02/06 08:06 AM (17 years, 9 months ago)

This is a really poor article, even for a shit rag like The NewScientist.

It doesn't make the slightest bit of sense. You're not pregnant until the embryo implants. It's impossible to harm a pregnancy before it happens. If you want to try to say that pregnancy happens upon fertilization then you'd have to say that birth control users are performing monthly abortions. That's just stupid.


-FF

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OfflineExplosiveMango
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Re: Marijuana May Cause Pregnancies To Fail [Re: fastfred]
    #5924818 - 08/02/06 09:24 AM (17 years, 9 months ago)

Quote:

fastfred said:
This is a really poor article, even for a shit rag like The NewScientist.

It doesn't make the slightest bit of sense. You're not pregnant until the embryo implants. It's impossible to harm a pregnancy before it happens. If you want to try to say that pregnancy happens upon fertilization then you'd have to say that birth control users are performing monthly abortions. That's just stupid.


-FF




Agreed. Very sketchy article.


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Know your self.
Know your substance.
Know your source.

The most distorted perspective possible is the perspective that yours is not distorted.

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OfflineExplosiveMango
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Re: Marijuana May Cause Pregnancies To Fail [Re: ExplosiveMango]
    #5924831 - 08/02/06 09:31 AM (17 years, 9 months ago)

Quote:


FROM ww.forbes.com/forbeslife/health/feeds/hscout/2006/08/01/hscout534145

Dey and his team suppressed FAAH activity in the mice. This increased the level of anandamide, which mimics what happens when a woman smokes marijuana and increases the level of THC, which binds to the same receptor as anandamide.





(And why the f*ck not just use THC guys? Does it not do quite what you expect?)


--------------------
Know your self.
Know your substance.
Know your source.

The most distorted perspective possible is the perspective that yours is not distorted.

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Offlinedownlowfunk
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Re: Marijuana May Cause Pregnancies To Fail [Re: Schwip]
    #5925493 - 08/02/06 01:53 PM (17 years, 9 months ago)

Quote:

Schwip said:
Read the article again downlowfunk.

It states that THC causes complications around the time of conception.

Not 8 or 9 months into it.




Yeah whatever,  both my niece and nephew were conceieved while the parents where using MJ, and Psilocybe.  and those kids are genius's ok well the niece is a crazy Chica, but still aptly gifted in dance and singing.  Again this article is propaganda nonesense F the Government and their propaganda studies :mushroom2:

Edited by downlowfunk (08/02/06 02:04 PM)

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OfflineBGC
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Re: Marijuana May Cause Pregnancies To Fail [Re: downlowfunk]
    #5928705 - 08/03/06 02:16 PM (17 years, 9 months ago)

Yet another bogus one I've spotted lately.

I read in High Times about how British research FOUND that cannabis DID NOT hurt the fetus in times of birth.

This is garbage. :rofl2:


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Offlinebongoboy2000
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Re: Marijuana May Cause Pregnancies To Fail [Re: BGC]
    #5934065 - 08/05/06 09:59 AM (17 years, 9 months ago)

I say GOOD! Too many damn people on this planet anyways. Even if it is true, it's not like drinking alcohol and smoking cigarettes is OK if you're trying to get preagnant. The problem is, no one will ever hear this warning because it's illegal to provide informative information about things like pot.
Just a safe, natural alternative to birth control pills. What CAN'T this drug do!!?


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...I got nothin..

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OfflinePregnant Friend
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Re: Marijuana May Cause Pregnancies To Fail [Re: downlowfunk]
    #8549165 - 06/21/08 11:29 PM (15 years, 10 months ago)

What do you think about the effects smoking marijuana.  Smoked only once around 7-8 weeks along --- can a very rapid heartbeat cause harm to an unborn fetus??? 

Edited by Pregnant Friend (06/21/08 11:35 PM)

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Invisiblealphabeatu
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Re: Marijuana May Cause Pregnancies To Fail [Re: Jfisher]
    #8549973 - 06/22/08 06:40 AM (15 years, 10 months ago)

it almost reads marijuana kills infants


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OfflineVisionary Tools
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Re: Marijuana May Cause Pregnancies To Fail [Re: fastfred]
    #8550472 - 06/22/08 12:08 PM (15 years, 10 months ago)

Quote:

fastfred said:
This is a really poor article, even for a shit rag like The NewScientist.

It doesn't make the slightest bit of sense.  You're not pregnant until the embryo implants.  It's impossible to harm a pregnancy before it happens.  If you want to try to say that pregnancy happens upon fertilization then you'd have to say that birth control users are performing monthly abortions.  That's just stupid.


-FF




It's just more whoring masquerading as journalism. Anyone with the cash can get their opinions published in what used to be a credible journal.  The BBC is much the same.

Well, the BBC breaks the law though.

Quote:

Put Personal Name & Address here
Put Date Here.


Sir Michael Lyons
The Chairman,                                                                                                                                          By 1st Class Post
BBC,                                                                                                                                                          Recorded Delivery.
Broadcast centre,
201 Wood lane,
London
W12 7TP

Dear Sir Michael Lyons

Re: The Royal Charter of the BBC, & the Treason & Felony Act, 1848
Notice Before Action.

It has been brought to my attention that the Corporation has received and is now receiving substantial amounts of funding from the European Union, in breach of Charter Provisions, and that in consequence of this very suspect arrangement the BBC is now reduced to the function of providing both broadcasting & propaganda facilities to a form of alien authority that fails to acknowledge the Supreme Authority of the British Crown.

I must advise you that all such conduct serves to breach the provisions of the Treason Act, 1351 with the further provisions of the Treason & Felony Act, 1848.

In addition, I must advise that the Treason & Felony Act of 1848 provides that it is a Criminal Offence for Subjects of the Crown to give aid or comfort to Traitors, and that this offence is punishable by imprisonment for life.

I am concerned for my own position and I must ask you to cease and desist from all treacherous conduct & financial arrangements, without delay.

Unless I receive your written assurance that the Corporation will issue an immediate public apology for all Treason committed thus far, with your further guarantee that the Corporation will cease and desist from all and any conduct that fails to maintain the Supremacy of the British Crown, then I must give fair warning of my intention to discontinue the payment of all such moneys as are now being applied to the financial support of the BBC.

I look forward to receipt of your immediate response to this present letter and I give notice that payments in support of the BBC will be suspended, unless I receive a satisfactory response within 14 days of this present date.

Yours faithfully,




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