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1. Powder mushrooms in blender

2. soak powder in 140 proof ethanol = 70 percent alcohol. Soak for 12 hours (or so), in the fridge but
roomtemp is probably OK too.

2a)Then pour the liquid through an old white t-shirt or so in a 2nd jar. Fill a syringe with it,
attach a filter and empty the syringe in jar no. 3
The filtration can be done with a disposable 0.2 micrometer liquid filter for
syringes (handpowdered, so no electricity or adspirator is needed) because you do not need to
save the insoluble particles. The filter can be discarded.

3. evaporate the liquid (big shallow dish, table fan) to 1/10 of the volume
(until it has just not begun to crystallize out)

4. add a few drops of hydrochloric or muriatic acid to convert all ionic and freebase alkaloids into salts

5. put the acidified extract in a tall vial

6a. remove resins with naphta or petroleum ether. These liquids float on top of the extract. To remove the
resins, just add naphta or pet ether, shake, let settle and remove/separate the layers with a pipette or
syringe. Discard the naphta/pet ether.
6b. repeat step 6a.

7. Now add acetone and repeat step 6a+6b.
7a) wash with 95 percent alcohol (cold)

The dark granular stuff which remains is a mixture of alkaloids. Among those are the alkaloids you want.

8. Add 190 proof or 95-96 percent ethanol (denatured alcohol is no problem as long it is denatured with
methanol or acetone). Close the vial and place it in boiling water. If you have a small,
thick walled glass bottle or vial you can even place it in a pc.

9. Wait until the vial is of the same temperature, take it out of the water and allow it to
cool down to slightly below the boiling point of the ethanol (so you can safely open the lid)
Suck up the liquid in a syringe, filter it and allow it to cool down slowly.

9a) The fine white crystals which precipitate
(rain down) as first from the solutiuon is what you are looking for.
White psilly crystals precipitate, urea stays in solution
(as long as you don't evaporate the liquid too far of course).

10. Remove the excess liquid with a pipette or syringe. Save the crystals.

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micro said:psilocybin seems to dissolve in protic solvents when acidified -- why would adding HCL make it precipitate out of an alcohol?

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