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InvisibleOneMoreRobot3021
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Excellent Article on Mushrooms on front page of CNN.com!
    #5845281 - 07/11/06 12:13 AM (17 years, 6 months ago)

(I'm aware this was posted in Shroomery News Service, but I dunno, this seems really big to me! I thought it deserved a place in the Pub, cross-posting be damned!!)

Mushrooms produce mystical experiences

NEW YORK (AP) -- People who took an illegal drug made from mushrooms reported profound mystical experiences that led to behavior changes lasting for weeks -- all part of an experiment that recalls the psychedelic '60s.

Many of the 36 volunteers rated their reaction to a single dose of the drug, called psilocybin, as one of the most meaningful or spiritually significant experiences of their lives. Some compared it to the birth of a child or the death of a parent.

Such comments "just seemed unbelievable," said Roland Griffiths of the Johns Hopkins University School of Medicine in Baltimore, Maryland, the study's lead author.

But don't try this at home, he warned. "Absolutely don't."

Almost a third of the research participants found the drug experience frightening even in the very controlled setting. That suggests people experimenting with the illicit drug on their own could be harmed, Griffiths said.

Viewed by some as a landmark, the study is one of the few rigorous looks in the past 40 years at a hallucinogen's effects. The researchers suggest the drug someday may help drug addicts kick their habit or aid terminally ill patients struggling with anxiety and depression.

It may also provide a way to study what happens in the brain during intense spiritual experiences, the scientists said.

Funded in part by the federal government, the research was published online Tuesday by the journal Psychopharmacology.

Psilocybin has been used for centuries in religious practices, and its ability to produce a mystical experience is no surprise. But the new work demonstrates it more clearly than before, Griffiths said.

Even two months after taking the drug, pronounced SILL-oh-SY-bin, most of the volunteers said the experience had changed them in beneficial ways, such as making them more compassionate, loving, optimistic and patient. Family members and friends said they noticed a difference, too.

Charles Schuster, a professor of psychiatry and behavioral neuroscience at Wayne State University in Detroit, Michigan, and a former director of the National Institute on Drug Abuse, called the work a landmark.

"I believe this is one of the most rigorously well-controlled studies ever done" to evaluate psilocybin or similar substances for their potential to increase self-awareness and a sense of spirituality, he said. He did not participate in the research.

Psilocybin, like LSD or mescaline, is one of a class of drugs called hallucinogens or psychedelics. While they have been studied by scientists in the past, research was largely shut down after widespread recreational abuse of the drugs during the 1960s, Griffiths said. Some work resumed in the 1990s.

"We've lost 40 years of (potential) research experience with this whole class of compounds," he said. Now, with modern-day scientific methods, "I think it's time to pick up this research field."

The study volunteers had an average age of 46, had never used hallucinogens, and participated to some degree in religious or spiritual activities such as prayer, meditation, discussion groups or religious services. Each tried psilocybin during one visit to the lab and the stimulant methylphenidate (better known as Ritalin) on one or two other visits. Only six of the volunteers knew when they were getting psilocybin.

Each visit lasted eight hours. The volunteers lay on a couch in a living-room-like setting, wearing an eye mask and listening to classical music. They were encouraged to focus their attention inward.

Psilocybin's effects lasted for up to six hours, Griffiths said. Twenty-two of the 36 volunteers reported having a "complete" mystical experience, compared with four of those getting methylphenidate.

That experience included such things as a sense of pure awareness and a merging with ultimate reality, a transcendence of time and space, a feeling of sacredness or awe, and deeply felt positive mood like joy, peace and love. People say "they can't possibly put it into words," Griffiths said.

Two months later, 24 of the participants filled out a questionnaire. Two-thirds called their reaction to psilocybin one of the five top most meaningful experiences of their lives. On another measure, one-third called it the most spiritually significant experience of their lives, with another 40 percent ranking it in the top five.

About 80 percent said that because of the psilocybin experience, they still had a sense of well-being or life satisfaction that was raised either "moderately" or "very much."


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Acid doesn't give you truths; it builds machines that push the envelope of perception. Whatever revelations came to me then have dissolved like skywriting. All I really know is that those few years saddled me with a faith in the redemptive potential of the imagination which, however flat, stale and unprofitable the world seems to me now, I cannot for the life of me shake.

-Erik Davis


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OfflineUlcerPentacidis
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: OneMoreRobot3021]
    #5845293 - 07/11/06 12:16 AM (17 years, 6 months ago)

Haha.

I just read this on another forum and was planning on posting it. Good read, and i can only hope this results in more positive exposure for psilocybin and hallucenogenic plants in general.


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µgrammar


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OfflineEmperorKuzco
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: OneMoreRobot3021]
    #5845303 - 07/11/06 12:21 AM (17 years, 6 months ago)

About god damn time the medical community took another look at psilocybin. This might be a step in the right direction toward de-criminalizing mushrooms.


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OfflineClammyJoe
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: EmperorKuzco]
    #5845306 - 07/11/06 12:22 AM (17 years, 6 months ago)

Wouldn't hold my breath on that, but its a step towards understanding.


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OfflinePurpleKush
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: OneMoreRobot3021]
    #5845320 - 07/11/06 12:25 AM (17 years, 6 months ago)

only 6 out of 46 people realized they were tripping? i would think it would have to be kind of obvious


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:blindfury::fried::psychsplit::vaped:


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InvisibleOneMoreRobot3021
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: ClammyJoe]
    #5845329 - 07/11/06 12:27 AM (17 years, 6 months ago)

Quote:

TheMadConductor said:
Wouldn't hold my breath on that, but its a step towards understanding.




Exactly! It's an open-minded article as far as its perspective on the research.

This article is going to be all over every newswire all over the world. Regular joes and janes are gonna sit down to their morning news and this is going to be a big part of it. The warning about not experimenting on your own is the smallest part of the article; by and large it's looking at the research in a very good light.

Baby steps!


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Acid doesn't give you truths; it builds machines that push the envelope of perception. Whatever revelations came to me then have dissolved like skywriting. All I really know is that those few years saddled me with a faith in the redemptive potential of the imagination which, however flat, stale and unprofitable the world seems to me now, I cannot for the life of me shake.

-Erik Davis


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Invisiblequiver
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: EmperorKuzco]
    #5845347 - 07/11/06 12:32 AM (17 years, 6 months ago)

i wouldnt bet on it


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InvisibleMezcal
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: OneMoreRobot3021]
    #5845392 - 07/11/06 12:42 AM (17 years, 6 months ago)

"Two months later, 24 of the participants filled out a questionnaire. Two-thirds called their reaction to psilocybin one of the five top most meaningful experiences of their lives. On another measure, one-third called it the most spiritually significant experience of their lives, with another 40 percent ranking it in the top five."

:grin:


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InvisibleSimisu
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: Mezcal]
    #5845853 - 07/11/06 04:47 AM (17 years, 6 months ago)

that's not the way to do research (not that i know exectly what they did)
why didn't they take people who already used mushrooms befor?
a study like this should be made under a diffrent setting then sitting in a room blindfolded listening to classical music :shrug:

i'd like to know what these people knew about mushrooms befor being given the dose (which was not mentioned BTW!)
were they given a recriational dose, lower or higher then?

i guess the actual study mentiones all those details but the report is kinda lacking... all it really tells me is that "psychodelics reaserch is valid and should be started again, this is just a teaser" which is not that bad but...

we should be thanking MAPS for this i'm pretty sure :tongue:


--------------------
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OfflineDfekt
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: Simisu]
    #5845871 - 07/11/06 05:11 AM (17 years, 6 months ago)

Thankyou for cross posting this or i never would have seen it!

Excellent news, that's made my day :grin:

Quote:

Two-thirds called their reaction to psilocybin one of the five top most meaningful experiences of their lives. On another measure, one-third called it the most spiritually significant experience of their lives, with another 40 percent ranking it in the top five.





I'm willing to bet those numbers would significantly increase if they had given them Ozric Tentacles to listen to instead of classical music!


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"Quotation is a serviceable substitute for wit." ~Oscar Wilde


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InvisibleSimisu
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: Dfekt]
    #5845877 - 07/11/06 05:21 AM (17 years, 6 months ago)

Quote:

MistaMiner said:
I'm willing to bet those numbers would significantly increase if they had given them Ozric Tentacles to listen to instead of classical music!




:yesnod::thumbup:


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:mushdance::sanpedro::peyote::mushroom2: :heart: Shr:supershroom::supershroom:mery :heart: :mushroom2::peyote::sanpedro::mushdance:
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Invisibleivi
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: Simisu]
    #5845879 - 07/11/06 05:23 AM (17 years, 6 months ago)

Quote:

Simisu said:
that's not the way to do research (not that i know exectly what they did)
why didn't they take people who already used mushrooms befor?
a study like this should be made under a diffrent setting then sitting in a room blindfolded listening to classical music :shrug:

i'd like to know what these people knew about mushrooms befor being given the dose (which was not mentioned BTW!)
were they given a recriational dose, lower or higher then?

i guess the actual study mentiones all those details but the report is kinda lacking... all it really tells me is that "psychodelics reaserch is valid and should be started again, this is just a teaser" which is not that bad but...

we should be thanking MAPS for this i'm pretty sure :tongue:




"The participants were hallucinogen-naïve adults reporting regular participation in religious or spiritual activities. Two or three sessions were conducted at 2-month intervals. Thirty volunteers received orally administered psilocybin (30 mg/70 kg) and methylphenidate hydrochloride (40 mg/70 kg) in counterbalanced order. To obscure the study design, six additional volunteers received methylphenidate in the first two sessions and unblinded psilocybin in a third session. The 8-h sessions were conducted individually. Volunteers were encouraged to close their eyes and direct their attention inward. Study monitors rated volunteers’ behavior during sessions. Volunteers completed questionnaires assessing drug effects and mystical experience immediately after and 2 months after sessions. Community observers rated changes in the volunteer’s attitudes and behavior."



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InvisibleSimisu
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: ivi]
    #5845888 - 07/11/06 05:31 AM (17 years, 6 months ago)

can you please link to the rest of it?


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Invisibleivi
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: Simisu]
    #5845897 - 07/11/06 05:38 AM (17 years, 6 months ago)



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Invisiblebadchad
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: ivi]
    #5845910 - 07/11/06 05:50 AM (17 years, 6 months ago)

The participants being drug naive was purposefully done. Thus, you would eliminate bias.

And no, MAPS had no part in this study.


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...the whole experience is (and is as) a profound piece of knowledge.  It is an indellible experience; it is forever known.  I have known myself in a way I doubt I would have ever occurred except as it did.

Smith, P.  Bull. Menninger Clinic (1959) 23:20-27; p. 27.

...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.

Osmond, H.  Annals, NY Acad Science (1957) 66:418-434; p.436


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InvisibleSimisu
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: badchad]
    #5845920 - 07/11/06 06:05 AM (17 years, 6 months ago)

don't know about you but it took me a while to rid my self of the bias to cannabis when i first started smoking...
it's hard for me to belive they didn't know they were given "drugs" so that's bound to make some sort of bias anyway!

if i'd make a research about mushrooms it would probably use people like shroomerites... that way you can consentrate on the effects of the drug on the spirit/mind with a better "vocabulary" (thought that's just my opinion :shrug:)
i belive drugs can be used as tools if people can be educted properly on the use of these drugs! there are many reports of amazing things happening betwine people while on high doses of mushrooms, things like telepathy and out of body expiriances... can these be duplicated? are they just imagination or fact? THATS what I want to know :tongue:

the fact that hallucinogens can create "mystical" or "religiuse" expiriances is nothing new and i could care less WHY it happens or how... that's for every person to decide for him self! i don't think it's the drug... it's all in the mind, the drug just lets it all happen?

p.s thanks ivi :grin:


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InvisibleSimisu
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: badchad]
    #5845961 - 07/11/06 06:55 AM (17 years, 6 months ago)

now  this (PDF) is an interesting article on Neurology!
this would certainly capture the imagination of many doctors around the world and hopefully someone is going to pick up the glove (and once they make some kind of cure from either psilocybin or LSD that would be news worthy :tongue: hopefully they won't be able to patent any drug to treat this other then simply the mushrooms or the acid...)

i have my own little theory on why it works but unfortunately i have no formal education to back it up with :smirk:


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OfflineIamthewalrus
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: badchad]
    #5845962 - 07/11/06 06:57 AM (17 years, 6 months ago)

Quote:

badchad said:
The participants being drug naive was purposefully done. Thus, you would eliminate bias.

And no, MAPS had no part in this study.




my thoughts exactly...if it were drug users this study would not be nearly as significant...this will give ppl who currently are biased against drugs a reason to question their beliefs and maybe even seak out personal treatment if they need it and join our side of the fence


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InvisiblePenguarky Tunguin
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: Iamthewalrus]
    #5846008 - 07/11/06 07:38 AM (17 years, 6 months ago)

Another great write up at Abcnews.com

http://abcnews.go.com/Health/story?id=2174998&page=1


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Every mistake, intentional or otherwise, in the above post, is the fault of the reader.


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Offlinecybrbeast
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: OneMoreRobot3021]
    #5849748 - 07/12/06 03:03 AM (17 years, 6 months ago)

Wow this article really has gotten a lot of coverage.



242 related articles  :shocked: :laugh:


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futuretribe.space


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OfflineEconomist
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: cybrbeast]
    #5849752 - 07/12/06 03:06 AM (17 years, 6 months ago)

Nice!

You know, with all the public debate about the benefits of Marijuana, I was kind of sad that my lil fun-guys would never get any media converage. It's refreshing to see this.


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InvisiblePinhead
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: OneMoreRobot3021]
    #5849923 - 07/12/06 05:58 AM (17 years, 6 months ago)

Quote from news article:
The volunteers were randomly assigned to take either 30 milligrams of psilocybin (chemically synthesized, not extracted from mushrooms) or 40 milligrams of methylphenidate, the stimulant sold as Ritalin.
http://www.washingtonpost.com/wp-dyn/content/article/2006/07/10/AR2006071001304.html

Ok, I was wondering, but too lazy to figure out how many grams of dried cubensis this dosage of "30 milligrams" would equal.


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InvisiblePinhead
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: Pinhead]
    #5850009 - 07/12/06 07:09 AM (17 years, 6 months ago)

Found this on MAPS site:
Potency and Dosage

Due to species variation, psilocybin mushrooms differ in potency. For example, concentrations of psilocybin in Psilocybe cubensis is about 2 mg/gm, whereas the quite potent Psilocybe semilanceata averages around 12.8 mg/gm in fresh specimens. Potency can also vary between strains of the same species, or even between various mushroom "flushings,"
=========================================
Ok, 2mg/gm of cubensis,does this mean they were given the equivalent of 15 gms. of dried cubensis? I know that this isn't 100% accurate because of the other active compounds in the natural source. Wow! still quite a hefty dosage!


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Invisiblesupercollider
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: Pinhead]
    #5850307 - 07/12/06 10:02 AM (17 years, 6 months ago)

They're talking about fresh grams, not dried. 15g fresh is a low-moderate dose.


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Supercollider? I just met her!


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OfflineClammyJoe
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: supercollider]
    #5850317 - 07/12/06 10:05 AM (17 years, 6 months ago)

They were probably given an equivalent, of 1 - 1.5 grams. Which is still a pretty good amount, especially in that kind of setting.


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InvisibleStonerguy
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: ClammyJoe]
    #5850448 - 07/12/06 10:50 AM (17 years, 6 months ago)

Really who wants to sit in a room blindfolded and listening to classical..  You need something to "touch" the senses. Wether it be flashing strobe lights and vicks, or the sun and the sweet smells of flowers.  I prefer the later for profound thinking :zoom:


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OfflineIamthewalrus
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: Stonerguy]
    #5850462 - 07/12/06 10:55 AM (17 years, 6 months ago)

this is excellent...actually a user posted in my thread concerning lsd as pain medication saying that a MAJOR study on psilocybin with truely amazing findings was gonna be published within a few months(this is it) and could be catalyst for a new era of research..but he admitted this may be wishful thinking...I'm curious how he knew about this :smile:

excellent!


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InvisibleSimisu
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: Iamthewalrus]
    #5850565 - 07/12/06 11:42 AM (17 years, 6 months ago)

they've been talking about this study (i'm assuming you're talking about the cluster head ache "study" right?) for a while... i've heard of it befor and looked into the clusterbusters web site and forums and they were gathering data for it!


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InvisibleHELLA_TIGHT
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: OneMoreRobot3021]
    #5850594 - 07/12/06 11:54 AM (17 years, 6 months ago)

Quote:

OneMoreRobot3021 said:

Psilocybin has been used for centuries in religious practices, and its ability to produce a mystical experience is no surprise. But the new work demonstrates it more clearly than before, Griffiths said.

Even two months after taking the drug, pronounced SILL-oh-SY-bin, most of the volunteers said the experience had changed them in beneficial ways, such as making them more compassionate, loving, optimistic and patient. Family members and friends said they noticed a difference, too.

Charles Schuster, a professor of psychiatry and behavioral neuroscience at Wayne State University in Detroit, Michigan, and a former director of the National Institute on Drug Abuse, called the work a landmark.

"I believe this is one of the most rigorously well-controlled studies ever done" to evaluate psilocybin or similar substances for their potential to increase self-awareness and a sense of spirituality, he said. He did not participate in the research.





:thumbup:


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OfflineIamthewalrus
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: Simisu]
    #5850676 - 07/12/06 12:27 PM (17 years, 6 months ago)

no this is different....he mentioned specific findings were gonna be published within the next couple months


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InvisibleLeft Nut City
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: Iamthewalrus]
    #5850762 - 07/12/06 12:58 PM (17 years, 6 months ago)

I tried to get in on that study at Hopkins (the school is right close to me) and they told me to bugger off because Iused tobacco and the study needed non-tobacco users.

They said that if they were ever going to do a study involving fuck-ups then I am right near the top of the list.

:grin:


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OfflineIamthewalrus
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: Left Nut City]
    #5850891 - 07/12/06 01:45 PM (17 years, 6 months ago)

LOL omg they really said that? hahahaha


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Invisiblesleepy
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: ClammyJoe]
    #6257984 - 11/07/06 03:50 PM (17 years, 2 months ago)

Quote:

TheMadConductor said:
They were probably given an equivalent, of 1 - 1.5 grams. Which is still a pretty good amount, especially in that kind of setting.




(30 mg/70 kg) 30 mg is what richard alpert was using at harvard. in that wierd setting i wouldn't even want to take that small of a dose


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OfflineGreat Scott
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: OneMoreRobot3021]
    #6258428 - 11/07/06 05:47 PM (17 years, 2 months ago)

These people are noobs, lol.  :lol:
Good for them, though.  Positive mainstream exposure is always good.


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OfflineHB
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Re: Excellent Article on Mushrooms on front page of CNN.com! [Re: OneMoreRobot3021]
    #6259161 - 11/07/06 07:58 PM (17 years, 2 months ago)

I think it's wild that they found exposure in the media ... and it's even more wild that they are having official federally-sponsored research with regular people on reasonable doses ...

but mushrooms should stay out of the media as much as possible to avoid creating any sort of strong feelings in people about them ...


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