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OfflineSherman901
Stranger
Registered: 08/17/05
Posts: 151
Last seen: 4 years, 19 days
Question of tolerance
    #5802148 - 06/29/06 04:14 AM (17 years, 7 months ago)

Yeah, this has been asked many times before but I couldn't find a thread that had this exact question. I'm buying a hit of acid and some mushrooms this weekend. I'm planning on taking acid one night and mushrooms the next. When I take acid it won't build up my tolerance for mushrooms as well, will it? I can trip on both just as strong as any other time, right?


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Offlinemellowrubberduck
NDE on 7/8/06
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Registered: 06/11/06
Posts: 241
Loc: Pennsylvania, USA
Last seen: 14 years, 3 months
Re: Question of tolerance [Re: Sherman901]
    #5802301 - 06/29/06 07:01 AM (17 years, 7 months ago)

I didn't think there was any type of cross-tolerance.


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Invisiblebadchad
Mad Scientist

Registered: 03/02/05
Posts: 13,372
Re: Question of tolerance [Re: mellowrubberduck]
    #5802331 - 06/29/06 07:27 AM (17 years, 7 months ago)

There should definetly be cross-tolerance. Both drugs are thought to work through very similar mechanisms of action (acting as 5-HT2A partial agonists).

I'm sure others will give you some first hand perspective though.


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...the whole experience is (and is as) a profound piece of knowledge.  It is an indellible experience; it is forever known.  I have known myself in a way I doubt I would have ever occurred except as it did.

Smith, P.  Bull. Menninger Clinic (1959) 23:20-27; p. 27.

...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.

Osmond, H.  Annals, NY Acad Science (1957) 66:418-434; p.436


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Offlinelsd25icu812
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Registered: 03/16/06
Posts: 596
Loc: United States
Last seen: 13 years, 7 months
Re: Question of tolerance [Re: badchad]
    #5802563 - 06/29/06 09:34 AM (17 years, 7 months ago)

yea there will defiantly be a noticeable difference. you should still be able to get high but it wont be the same at all. i would really suggest waiting a few days. eat the L first hehe


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love is what is left when you"ve let go of everything you love


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OfflineFunnyFaces
Epic Delusions
Registered: 06/25/06
Posts: 15
Last seen: 16 years, 10 months
Re: Question of tolerance [Re: lsd25icu812]
    #5802964 - 06/29/06 11:49 AM (17 years, 7 months ago)

I wouldn't worry too much about tolerance if you are taking only one hit of acid.  The mushrooms will still have a noticeable effect, but you may be psychologically drained and not be up for much introspection or real intensity.  I would say physically your body won't have much tolerance from one hit of acid, but you know, one hit of acid can go a long way towards changing your outlook and set going into another trip.  Not getting enough sleep and eating a poorly balanced diet would probably affect a trip just as much as the physical tolerance. 

You should also think about what you expect out of these experiences and if you are giving these substances the respect they deserve.  Remember to have fun, clear your mind, and remember what you learn  :grin:


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This is not me. I am nothing.


Edited by FunnyFaces (06/29/06 11:51 AM)


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Invisibledrijx
ҽӽҏҽґіᵯҽӣҭӧґ ғҽҁҽᴢᴢ
Male

Registered: 06/20/06
Posts: 310
Loc: Ⱥʍͼѓᴉᴋѧ
Re: Question of tolerance [Re: FunnyFaces]
    #5803428 - 06/29/06 02:13 PM (17 years, 7 months ago)

take them both the same night :laugh: . . . about your question, there is cross-tolerance between the two. Shouldn't cause any problem if you're just taking one hit though.


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