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North Spore Shop: Cultivation Supplies

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OfflineWeebl8bob
Psychonaut
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Registered: 06/14/06
Posts: 181
Loc: Ohio (USA) Flag
Last seen: 5 years, 2 months
BuSpar and hallucinogens..
    #5776957 - 06/21/06 03:39 PM (17 years, 7 months ago)

Hey just wondering if anyone has experience with the partial agonist/full antagonist (serotonin), BuSpar and hallucinogens. How was the trip altered?


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"You can turn your back on a person, but never turn your back on a drug, especially when its waving a razor sharp hunting knife in your eye." - Hunter S. Thompson


Edited by Weebl8bob (06/21/06 07:01 PM)


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Invisiblebadchad
Mad Scientist

Registered: 03/02/05
Posts: 13,372
Re: BuSpar and hallucinogens.. [Re: Weebl8bob]
    #5777196 - 06/21/06 05:02 PM (17 years, 7 months ago)

Good question. Actually, buspar is a partial agonist at the 5-HT1A receptor.

Animal studies suggest it will increase the effects.


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...the whole experience is (and is as) a profound piece of knowledge.  It is an indellible experience; it is forever known.  I have known myself in a way I doubt I would have ever occurred except as it did.

Smith, P.  Bull. Menninger Clinic (1959) 23:20-27; p. 27.

...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.

Osmond, H.  Annals, NY Acad Science (1957) 66:418-434; p.436


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OfflineWeebl8bob
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Registered: 06/14/06
Posts: 181
Loc: Ohio (USA) Flag
Last seen: 5 years, 2 months
Re: BuSpar and hallucinogens.. [Re: badchad]
    #5777597 - 06/21/06 07:00 PM (17 years, 7 months ago)

Really? Hmm... How interesting.. Any numbers you could estimate? I read that it was partial agonist/full antagonist... Hmm... This is really interesting now :-)


--------------------
"You can turn your back on a person, but never turn your back on a drug, especially when its waving a razor sharp hunting knife in your eye." - Hunter S. Thompson


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Invisiblebadchad
Mad Scientist

Registered: 03/02/05
Posts: 13,372
Re: BuSpar and hallucinogens.. [Re: Weebl8bob]
    #5777621 - 06/21/06 07:06 PM (17 years, 7 months ago)

Whats more important is WHICH receptors it has actions upon.

The study was performed in a controlled laboratory environment, with rodents. Thus, "how much" is impossible to tell, given the variables: unknown dose (in a recreational setting), what type of "hallucinogen" you're talking about (the study used LSD), and whether or not you can even extrapolate animal data to humans (previous research suggests a definite "yes" to this question, but you never know). If you try this, keep track of the things you do (dose, time etc.) and let me know what happens.


--------------------
...the whole experience is (and is as) a profound piece of knowledge.  It is an indellible experience; it is forever known.  I have known myself in a way I doubt I would have ever occurred except as it did.

Smith, P.  Bull. Menninger Clinic (1959) 23:20-27; p. 27.

...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.

Osmond, H.  Annals, NY Acad Science (1957) 66:418-434; p.436


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OfflineWeebl8bob
Psychonaut
Male
Registered: 06/14/06
Posts: 181
Loc: Ohio (USA) Flag
Last seen: 5 years, 2 months
Re: BuSpar and hallucinogens.. [Re: badchad]
    #5777684 - 06/21/06 07:20 PM (17 years, 7 months ago)

Well Idunno, ill look for more information but if i get mixed stories or more than a few "I wouldnt do its" Im gunna have to say no..


--------------------
"You can turn your back on a person, but never turn your back on a drug, especially when its waving a razor sharp hunting knife in your eye." - Hunter S. Thompson


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North Spore Shop: Cultivation Supplies


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