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Invisiblekaniz
That one, overthere.
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Registered: 07/23/04
Posts: 4,166
Loc: Ontario
How strong is the LSD/mushroom cross-tolerance?
    #5660422 - 05/22/06 02:27 PM (17 years, 8 months ago)

Well, I just booked all my tickets for a Vacation up to Montreal for the end of the month. Going up for the Mutek Music Festival, and really looking forward to the events on the Sat and Sunday afternoons.

The setting is a beautiful outdoor park, the music is a lineup of DJs which are pretty much my top 5 favorites.

I was planning on doing Mushrooms on the Sat, the 'lesser' of the two parties, just kick back and relax a bit, and not do that big of a dose.

However on the Sunday, its Hawtin, Magda, Ricardo Villolobs, Marc Houl, etc -- a M_NUS showcase day, and I'm planning on doing LSD that day also (party runs from around 1pm untill 11pm), and will prob be doing around 2 or 3 hits of some really good blotter.

Anywho, it then dawned on me 'isnt there a cross-tolerance between the two?' There will be around a 24hour timeframe between the two, and I have mixed mush+LSD before.

Soo, long post short : How much of a cross tolerance is there? will it totatly flaten the LSD trip, or will I just need to up the dosage a bit?

If need be, I'm fine with just going with some weed and booze on the Sat and saving myself for the Sunday -- but, outdoor minimal techno in a picture perfect location is just begging for some mushrooms :smile:


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OfflineHerbus
...

Registered: 10/19/04
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Re: How strong is the LSD/mushroom cross-tolerance? [Re: kaniz]
    #5660437 - 05/22/06 02:29 PM (17 years, 8 months ago)

I was going to post a similiar question...

I'm curious about cross-tolerance, too.

But since you'd know, having done the two at the same time, what that's like?

Do they work "collectively" to make the trip stronger, or does it dilute it, or is there no noticable difference?


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Invisiblekaniz
That one, overthere.
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Registered: 07/23/04
Posts: 4,166
Loc: Ontario
Re: How strong is the LSD/mushroom cross-tolerance? [Re: Herbus]
    #5660460 - 05/22/06 02:34 PM (17 years, 8 months ago)

It's hard to say -- they did mix, and did add a bit of an intensity, but it wasnt really in an 'ideal' setting to really explore the trip.

I had done 2 hits of LSD on my way to a rave, get inside - hour or two pass by and I'm thinking I'm not really tripping. Friend of mine had some mush left that I had given him earlier, so ate a bit of that -- not sure how much I ate, maybe 1.5 or 2g

It did add a 'flavor' to the trip - and the OEVs started to get interesting and not what I typically get on LSD and it did add a certian level of confusion, but I remeber saying "I'm just confused enough to really enjoy it" (I liked it).

But, since I was in a club with LOADS of stimulation going on, I didnt really get a chance to immerse myself into the expierence. It wasnt untill I left the club that it seemed like the LSD and Mush hit me full tilt -- but was starting to get to the end of the peak (around 6 hours after dropping the LSD, and maye 4 hours of the Mushrooms).

It did add to the trip and there was a noticable difference, which makes me wonder just how strong the cross tollerance will be?


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OfflineLedHead
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Re: How strong is the LSD/mushroom cross-tolerance? [Re: Herbus]
    #5660466 - 05/22/06 02:35 PM (17 years, 8 months ago)

i would say its enough to extremely lesson ur 2-3 hits. the first time i ever did acid i tripped on mushrooms 3 days prior. i had wanted to do acid for a very long time and my roomie suprised me with some hits 3 days after th emushroom trip. he tripped, i barely felt it. now mind u we only took 2 hits of low to medium grade blotter but 2 hits was enough to send my friend into a decent trip that lasted 8 hours or a little less... i had threshold effects


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I'm a traveler of both time and space...


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InvisibleMezcal
Registered: 08/11/05
Posts: 1,980
Re: How strong is the LSD/mushroom cross-tolerance? [Re: kaniz]
    #5660495 - 05/22/06 02:41 PM (17 years, 8 months ago)

tripping two days in a row has never really been fun for me. if anything is going down (festival, etc) i will usually resort to rolling one night and tripping or flipping the second.

i'd recommend taking your normal LSD dose with a little bit of mushrooms. it gets pretty intense together, but it's worth trying once or twice.


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Offlinedalmonk
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Re: How strong is the LSD/mushroom cross-tolerance? [Re: Mezcal]
    #5660547 - 05/22/06 02:53 PM (17 years, 8 months ago)

A few weeks ago my friend and I ended up tripping on both Friday and Saturday on small-mid sized dosages of mushrooms (2 grams Friday, 1.5 Saturday). I had a really enjoyable time both nights, but this is beside the point. My friend who took similar dosages founded out on Sunday that he could get acid (which is tremendously rare around here) so he ended up taking a hit on Sunday and then another hit the next day as well. He claimed that he didn't really feel any kind of negative effects from dosing this regularly and that there was no noticable lessening in intensity from day to day due to tolerance.

I'm not saying that cross tolerance won't have an effect on subsequent trips, but I think that it's not as big a factor as some would have you believe.


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Invisiblekaniz
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Re: How strong is the LSD/mushroom cross-tolerance? [Re: dalmonk]
    #5660558 - 05/22/06 02:56 PM (17 years, 8 months ago)

^ Yeah, when I first started doing mushrooms, there were a few times where I would trip two days in a row, or with only 1 day inbetween, and found that the mush tollerance was never as much as other people said it was.


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OfflineLedHead
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Re: How strong is the LSD/mushroom cross-tolerance? [Re: kaniz]
    #5660704 - 05/22/06 03:30 PM (17 years, 8 months ago)

i dunno man, from my experience it made a difference. im not talking about taking mushrooms twice in a row im talking about tripping balls on mushrooms and than taking acid 3 days later and it definately being weaker than my friend who tripped on the same ammount of cid of the exact same blotter. he tripped i didnt


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I'm a traveler of both time and space...


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Offlinewiggles
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Re: How strong is the LSD/mushroom cross-tolerance? [Re: LedHead]
    #5660730 - 05/22/06 03:37 PM (17 years, 8 months ago)

Both chemicals are based around the amphetamine ring, so it would make some sense that they all have some cross tolerance, wouldn't it?


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You can turn your back on a person, but never turn your back on a drug, especially when its waving a razor sharp hunting knife in your eye.
Hunter S. Thompson


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Invisiblebadchad
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Registered: 03/02/05
Posts: 13,373
Re: How strong is the LSD/mushroom cross-tolerance? [Re: wiggles]
    #5660946 - 05/22/06 04:51 PM (17 years, 8 months ago)

Both are hypothesized to have very similar mechanisms of action (partial agonists at the 5-HT2A recptor). It's downregulation of this receptor which is thought to result in the rapid development of tolerance.

Thus, it makes perfect sense they would exhibit cross-tolerance.


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...the whole experience is (and is as) a profound piece of knowledge.  It is an indellible experience; it is forever known.  I have known myself in a way I doubt I would have ever occurred except as it did.

Smith, P.  Bull. Menninger Clinic (1959) 23:20-27; p. 27.

...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.

Osmond, H.  Annals, NY Acad Science (1957) 66:418-434; p.436


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Invisiblekaniz
That one, overthere.
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Registered: 07/23/04
Posts: 4,166
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Re: How strong is the LSD/mushroom cross-tolerance? [Re: badchad]
    #5660980 - 05/22/06 05:05 PM (17 years, 8 months ago)

as I said, I'm aware that there is a cross tollerance, just curious to how strong of one it is. If I need to like, 3x my dose - I'll stick with going sober, but, if its 'oh, a bit of one -- slight reduction', then I'd do them both.

But, seeing as I'd rather make the most of my sunday and dont want to risk nullifying my trip, I think I'll just smoke some weed and drink on the Sat.


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OfflineKingkole
im not a noob...im a a doob

Registered: 11/30/03
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Re: How strong is the LSD/mushroom cross-tolerance? [Re: kaniz]
    #5661370 - 05/22/06 07:06 PM (17 years, 8 months ago)

Mabye you can make some powerful weed brownies, enough to make you have a whole lot of fun on sat?


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Invisiblekaniz
That one, overthere.
Male

Registered: 07/23/04
Posts: 4,166
Loc: Ontario
Re: How strong is the LSD/mushroom cross-tolerance? [Re: Kingkole]
    #5661457 - 05/22/06 07:27 PM (17 years, 8 months ago)

Hrmmm, now that's a good idea :smile:


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InvisibleEasy_Cheese
Cheese in a can

Registered: 05/12/06
Posts: 62
Re: How strong is the LSD/mushroom cross-tolerance? [Re: kaniz]
    #5661537 - 05/22/06 07:47 PM (17 years, 8 months ago)

Once i went to a 3 day phish show.I took a ten strip with me and planned on getting all fucked up the whole 3 days but just tripping one time,the last night.We planned on eating 5 a piece our last night.Anyway on the first night i was really gone because i bought a tray of brownies off a head who was tripping ballz.He came stumblin up and said he would trade the whole tray for a beer,a roll your own of Drum he saw me smoking and $15.They were so dank smellinng you wouldnt believe it.
Anyway the point is iwas shot from 1/2 the tray and i decided to get some shrooms so i scored an 1/8th and wolfed them down...tripped like mad.
About 36 hours later i ate my 5 hits of acid and it blew me away.As long as you take it easy with the shrooms and have good quality acid youll be fine,just make sure you drop all the hiits at once dont space them out and if it were me i would eat maybe 2 graams shrooms but drink my ass off and geta good nights rest,then take 4 hits.


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....Said the can of Cheese!


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