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OfflineCeeD
Stranger
Registered: 05/04/06
Posts: 1
Last seen: 17 years, 8 months
Opiate/Oxycodone Use with Mushrooms- Safe?
    #5591183 - 05/04/06 07:24 PM (17 years, 8 months ago)

Hey, first post, and what a great site!

I take short acting (4 hour) 10 mg oxycodone 4x daily for chronic pain for 1/2 a year now.  I have a tollerance (no euphoria or other high dose side effects).

I have been trying to find the possible interactions between oxycodone and mushrooms but have found nothing.

How do opiates interact with psilocybin?  Are there any possible interactions or contradictions?  Thank you!

I have read that psilocybin and opiates act on the opiate receptors within the brain, and I would hate to have some sort of compounding effect; I'm going to wait to hear back before doing them. :wink:

Thanks very much!


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Offlinethe_psychonaut
psychonaut
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Registered: 01/09/05
Posts: 394
Last seen: 8 years, 5 months
Re: Opiate/Oxycodone Use with Mushrooms- Safe? [Re: CeeD]
    #5591215 - 05/04/06 07:29 PM (17 years, 8 months ago)

in my experiences with high doses of stronger opiates, id say u will be fine i fu r only taking 10 mg oxycodone. i do have to say it may slightly dull the trip, but it would probably just be better to take an extra .5 or something than deal with pain while tripping. i experienced no negative side effects in my experience, unless u call sleeping like a baby after the trip a side effect. have fun


--------------------
never be afraid to let your mind explore, just know what you are getting into b4 you jump in the deep end, and do your research on this site and erowid.com


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OfflineNashbar
just strange.... on drugs
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Registered: 07/16/05
Posts: 3,536
Loc: strawberry field
Last seen: 6 years, 3 months
Re: Opiate/Oxycodone Use with Mushrooms- Safe? [Re: the_psychonaut]
    #5591383 - 05/04/06 07:55 PM (17 years, 8 months ago)

same for heroin or any opiate?


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OfflineLion
Decadent Flower Magnate
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Registered: 09/20/05
Posts: 8,775
Last seen: 3 days, 23 hours
Re: Opiate/Oxycodone Use with Mushrooms- Safe? [Re: Nashbar]
    #5591564 - 05/04/06 08:33 PM (17 years, 8 months ago)

but but but... why?


--------------------
“Strengthened by contemplation and study,
I will not fear my passions like a coward.
My body I will give to pleasures,
to diversions that I’ve dreamed of,
to the most daring erotic desires,
to the lustful impulses of my blood, without
any fear at all, for whenever I will—
and I will have the will, strengthened
as I’ll be with contemplation and study—
at the crucial moments I’ll recover
my spirit as was before: ascetic.”


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InvisibleEternalCowabunga
Being of Great Significance
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Registered: 04/04/05
Posts: 7,152
Loc: Time and Space
Re: Opiate/Oxycodone Use with Mushrooms- Safe? [Re: Nashbar]
    #5591575 - 05/04/06 08:34 PM (17 years, 8 months ago)

Did this combination just a few weeks ago; I took 40 mg of oxycodone while on 1.5 grams of shrooms. If anything it just made me more relaxed and sort of sleepy. It felt good though, it was a good combo along with some good weed. Anyway, it's safe. have a good time


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InvisibleLand_Crab
NeuroticPsychonaut
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Registered: 08/29/04
Posts: 2,194
Loc: U.S.
Re: Opiate/Oxycodone Use with Mushrooms- Safe? [Re: CeeD]
    #5592067 - 05/04/06 10:44 PM (17 years, 8 months ago)

Opiates are safe to mix with mushrooms, because they both work in completely different way in the brain. Put simply, opiates act primarily on the neurotransmitter dopamine, whereas mushrooms act on the neurotransmitter serotonin.

Physically, mushrooms are extremely safe, and impossible to overdose on (unless you have a syringe and a ton of pure psilocybin.)
Opiates by themselves (can) cause a drop in body temperature, blood pressure, and suppress respiration (to the point of death.) So if you're using the opiates safely enough to begin with, which you are, you'll be fine.

As a rule of thumb, the well-established, natural psychedelic drugs such as mescaline, psilocybin, DMT -- as well as marijuana, do not produce any adverse, health-endangering physical effects. They may slightly increase your heart rate and blood pressure, and could possibly make you nauseous or dizzy (and sometimes twitchy or induce "phantom pains.") But if you are healthy (i.e. you don't have an underlying heart condition,) they are extremely safe, and have thousands upon thousands of years of human use to back that up.


Edited by Land_Crab (05/04/06 11:01 PM)


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OfflineCUBErt
Connoisseur ofHallucination
Male

Registered: 08/24/05
Posts: 1,067
Loc: Southern CA
Last seen: 14 years, 3 months
Re: Opiate/Oxycodone Use with Mushrooms- Safe? [Re: Nashbar]
    #5592081 - 05/04/06 10:49 PM (17 years, 8 months ago)

Quote:

Nashbar said:
same for heroin or any opiate?




Yes any opiate dosage that is safe for you. If you are looking for just a really chilled out trip, I have had a  :thumbup: great time with heroin and mushrooms. But I can tell you, it really killed alot of the spiritual/higher consciousness aspects of the trip. I spent alot of the time just lying there, completely unaware that myself or anything existed. Now sure this happens with just mushrooms but I definitely noticed alot less of the higher thinking and more of just a sedated trip


--------------------
-CUBErt
:cubie::levitate::cubie:


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