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InvisibleAmatoxin
Injected With A Poison

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Chilli causes cancer cells to commit suicide
    #5409787 - 03/16/06 06:54 PM (17 years, 10 months ago)

Being a chilli head this caught my eye  :laugh:

Quote:

Pepper 'kills prostate cancer'

http://news.bbc.co.uk/1/hi/health/4805190.stm

The ingredient which makes jalapeno peppers hot also makes prostate cancer cells commit suicide, a study suggests.

Tests showed that capsaicin triggered 80% of the cells to start the process leading to cell death.

The US research in the journal Cancer Research also found tumours treated with capsaicin were smaller.

UK prostate experts say capsaicin could be the basis of a future drug but warned eating too many hot peppers has been linked to stomach cancer.


We caution men with prostate cancer in the UK against upping their weekly intake of the hottest known chillies
Chris Hiley, The Prostate Cancer Charity

In the study, researchers from Cedars-Sinai Medical Center studied mice who had been genetically modified to have human prostate cancer cells.

They were given a dose of pepper extract equivalent to a man of 200 pounds (90.7kg) taking 400 milligrams of capsaicin three times a week.

That would be the same as having between three and eight fresh habanero peppers - the highest rated peppers for capsaicin content.

Normal cells go through a constant process where millions die every second - a process called apoptosis - while millions more are made, to keep the numbers the same.

But cancer cells avoid that process and "dodge" apoptosis by mutating or deregulating the genes that participate in programmed cell suicide.

Capsaicin was seen to increase the amount of certain proteins involved in the apoptosis process.

Capsaicin also reduced the amount of prostate-specific antigen (PSA), a protein whch is often produced in high quantities by prostate tumours.

Fish intake

Dr Soren Lehmann, who led the study, said: "Capsaicin had a profound anti-proliferative effect on human prostate cancer cells in culture.

"It also dramatically slowed the development of prostate tumours."

Chris Hiley, head of policy and research at The Prostate Cancer Charity, said: "This is interesting laboratory-based work on cells but we don't yet know how, if at all, it might help men with prostate cancer.

"Eventually, it may be possible to extract the capsaicin and make it available as a drug treatment.

"In the meantime we caution men with prostate cancer in the UK against upping their weekly intake of the hottest known chillies - high intake of hot chillies has been linked with stomach cancers in the populations of India and Mexico.

"For now, if men with prostate cancer want to improve their diet they should avoid fatty foods, eat less red and processed meat, increase their fish intake and enjoy a wide and plentiful range of fruit and vegetables every day."




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Offlinedaimyo
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Re: Chilli causes cancer cells to commit suicide [Re: Amatoxin]
    #5409795 - 03/16/06 06:56 PM (17 years, 10 months ago)

"They were given a dose of pepper extract equivalent to a man of 200 pounds (90.7kg) taking 400 milligrams of capsaicin three times a week.
That would be the same as having between three and eight fresh habanero peppers"


:crazy:


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"I have sworn upon the altar of God eternal hostility against every form of tyranny over the mind of man."


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Offlineunbeliever
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Re: Chilli causes cancer cells to commit suicide [Re: daimyo]
    #5409799 - 03/16/06 06:58 PM (17 years, 10 months ago)

Reminds me of a photoshop contest entry I did once..



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Invisibleeligal
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Re: Chilli causes cancer cells to commit suicide [Re: Amatoxin]
    #5409802 - 03/16/06 06:59 PM (17 years, 10 months ago)

:cruelworld:


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\m/ Spanksta \m/

"do you have the freedom to do with your nervous system what you want?"

"MolokoMilkPlus said:
I'll respect you if you let me give you a blow job"

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respect the can."



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InvisibleAmatoxin
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Re: Chilli causes cancer cells to commit suicide [Re: daimyo]
    #5409804 - 03/16/06 06:59 PM (17 years, 10 months ago)

Quote:

daimyo said:
"They were given a dose of pepper extract equivalent to a man of 200 pounds (90.7kg) taking 400 milligrams of capsaicin three times a week.
That would be the same as having between three and eight fresh habanero peppers"


:crazy:




I ingest about twice that amount per week!  :wink:


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OfflineDF2K
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Re: Chilli causes cancer cells to commit suicide [Re: Amatoxin]
    #5409806 - 03/16/06 06:59 PM (17 years, 10 months ago)

where exactly did it specify "chilli" again?


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OfflineDF2K
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Re: Chilli causes cancer cells to commit suicide [Re: DF2K]
    #5409807 - 03/16/06 07:00 PM (17 years, 10 months ago)

lol
im j/k

thats cool


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Offlinefresh313
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Re: Chilli causes cancer cells to commit suicide [Re: DF2K]
    #5409811 - 03/16/06 07:01 PM (17 years, 10 months ago)

i pour loads of crushed red pepper on everything.


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InvisibleAmatoxin
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Re: Chilli causes cancer cells to commit suicide [Re: DF2K]
    #5409817 - 03/16/06 07:02 PM (17 years, 10 months ago)

Quote:

DF2K said:
where exactly did it specify "chilli" again?




All chilli peppers contain the active ingredient 'capsaicin'


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OfflineTattoo
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Re: Chilli causes cancer cells to commit suicide [Re: fresh313]
    #5409823 - 03/16/06 07:04 PM (17 years, 10 months ago)

A family friend is suffering from colon cancer, I'll link this pronto


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Edited by Tattoo (03/16/06 07:26 PM)


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Invisibleblink
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Re: Chilli causes cancer cells to commit suicide [Re: Amatoxin]
    #5409825 - 03/16/06 07:04 PM (17 years, 10 months ago)

Quote:

Amatoxin said:
Quote:

DF2K said:
where exactly did it specify "chilli" again?




All chilli peppers contain the active ingredient 'capsaicin'




It's the HOT. :smile:

I love hot sauce, I'm safe! :wink:


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InvisibleAmatoxin
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Re: Chilli causes cancer cells to commit suicide [Re: blink]
    #5409838 - 03/16/06 07:08 PM (17 years, 10 months ago)

I grow my own chilli's and make my own hot sauce  :smile:

Got about 10 different types of homemade sauce in the cupboard, made a new batch today actually lolzz  :laugh:


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Invisibleblink
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Re: Chilli causes cancer cells to commit suicide [Re: Amatoxin]
    #5409862 - 03/16/06 07:15 PM (17 years, 10 months ago)

I need to start making more homemade... did it once and stopped.

might need to grow more peppers too


I reduced like 40 pounds into a pint of sauce

it was teh yum


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InvisibleAmatoxin
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Re: Chilli causes cancer cells to commit suicide [Re: blink]
    #5409939 - 03/16/06 07:42 PM (17 years, 10 months ago)

There's a couple of bits of bullshit info in the article though

Quote:

"Eventually, it may be possible to extract the capsaicin and make it available as a drug treatment."




You can extract pure capsaicin with ethanol, been done many times.

Quote:

UK prostate experts say capsaicin could be the basis of a future drug but warned eating too many hot peppers has been linked to stomach cancer.




80% of imported chilli products from third world countries are contaminated with higher than approved levels of aflatoxin, a carcinogenic fungus.


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