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OfflineMrMolotov
Ganja Patrol
Male

Registered: 06/12/05
Posts: 640
Loc: SoCal
Last seen: 14 years, 1 month
DMSO + salvia?
    #5367442 - 03/05/06 01:42 PM (17 years, 10 months ago)

Just got 4 grams of salvia leaves powdered from my headshop cus i bought a bowl and im wonderin would the salvinorium be carried across the skin by a DMSO70% and 30% gel solution?


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Offlinestumpjumper
Mushroom Hound

Registered: 12/01/05
Posts: 33
Last seen: 17 years, 8 months
Re: DMSO + salvia? [Re: MrMolotov]
    #5367761 - 03/05/06 03:28 PM (17 years, 10 months ago)

woa


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Invisibleredgreenvines
irregular verb
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Registered: 04/08/04
Posts: 37,534
Re: DMSO + salvia? [Re: MrMolotov]
    #5367803 - 03/05/06 03:38 PM (17 years, 10 months ago)

no it wont work
but
if you first extract all the salvinorin from ~6 grams of leaf you will have one oral dose, and you can administer that dose orally using DMSO.

the skin is way way way too slow.

gut is slower than lungs but DMSO will be a good vehicle - better than alcohol.

still the lungs are ~30 times more efficient than the gut for absorbing vaporized salvinorin or combusted salvia leafs.


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OfflineKaleidoscope
Voodoo Child
Registered: 12/02/05
Posts: 674
Loc: the 28th dimension
Last seen: 16 years, 11 months
Re: DMSO + salvia? [Re: redgreenvines]
    #5368018 - 03/05/06 05:05 PM (17 years, 10 months ago)

wait, I thought DMSO was something the army used to make it's chemical weapons effective through the skin...


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Purple haze, all in my brain, lately things just don't seem the same. Actin' funny but I don't know why, 'scuse me while I kiss the sky.


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Invisibleredgreenvines
irregular verb
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Registered: 04/08/04
Posts: 37,534
Re: DMSO + salvia? [Re: Kaleidoscope]
    #5369874 - 03/06/06 05:11 AM (17 years, 10 months ago)

salvinorin needs a threashold transfer of at least 6 micrograms per second to the blood for a sustained 60 seconds to threashold into psychedelic effects
DMSO works too slowly for that threashold to be managed through the skin.
but if you take about 1500mg salvinorin orally with DMSO you will get better results than commercial alcohol based tinctures.

note the dose would be ~40 times higher than for smoking.


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