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OfflineAround In Circles
Eternally Recurring

Registered: 01/29/06 Happy 18th Shroomiversary!
Posts: 1,118
Last seen: 14 hours, 13 minutes
Pupil Dilation
    #5253600 - 02/01/06 11:17 PM (18 years, 5 hours ago)

What exactly triggers the dilation of pupils from psilocybin? It must be due to melatonin production, but why? My pupils often get so large when I trip that people say I look like a cartoon character, that they can't even see the color of my eyes. What is behind this?


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"When you get the message, hang up the phone." - Alan Watts

We Die to Remember What We Live to Forget


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Offlinesome1whoisntme
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Registered: 09/21/05
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Re: Pupil Dilation [Re: Around In Circles]
    #5253629 - 02/01/06 11:26 PM (18 years, 5 hours ago)

The windows to your soul are opening, man. :mushroom2:


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"Ignore the distortion you're forced to percieve and believe that what supercedes is love, but who agrees?"


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Offlinestemmer
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Re: Pupil Dilation [Re: Around In Circles]
    #5253643 - 02/01/06 11:30 PM (18 years, 5 hours ago)

Pupil dialation is a sign of brain damage. In the case of hallucinogenic drugs, it is due to different chemical reactions in the brain that are not normal. For example, (these are afew of the reasons):

Pupil Dilation

Adrenaline

Adrenaline secretion causes pupil dilation.

? Adrenaline: Effects: Vision



Amblyopia

Atropine eyedrops may be used to treat amblyopia by causing the pupil of one eye to dilate [normally both pupils dilate and contract together, even if one is blocked], and blur vision.

? Vision: Binocular Functions: Amblyopia: Treatment: Passive Treatment (Occlusion)



Chronic Dilation of the Pupil

An Excess of Endorhpins?

Can chronic dilation of the pupil, caused by adrenaline secretion, cause the body to release an excess or endorphins when the eyes are exposed to bright light?

? The Brain: Endorphins: An Excess of Endorphins

? Light Sensitivity: Causes: Stimulants, Medications (chronic dilation of the pupil)



Are therapies such as

? Light therapy for Seasonal Affective Disorder or

? Syntonics

helpful in preventing an excess of endorphins by causing the pupil to contract, even though exposure to light may be increased?



Can exercises such as palming be helpful in preventing an excess of endorphins by

? Reducing stress and adrenaline secretion and

? Blocking light to the eyes,

even though a lack of light will cause the pupils to remain dilated?



Sleep Deprivation and Dopamine

Research Topics: Sleep Deprivation:

? Antidepressant Effects, Dopamine

? Eye-Blink Rate, Dopamine

? Effect on the Frontal Lobes

? Adrenaline

? Related Topics



Dopamine:

? The Brain: Dopamine: Dopamine Levels: Limbic System, Too Much Dopamine


Edited by stemmer (02/01/06 11:31 PM)


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OfflineAround In Circles
Eternally Recurring

Registered: 01/29/06 Happy 18th Shroomiversary!
Posts: 1,118
Last seen: 14 hours, 13 minutes
Re: Pupil Dilation [Re: Around In Circles]
    #5253662 - 02/01/06 11:35 PM (18 years, 4 hours ago)

Thanks, but that doesn't seem to answer my question.

Any chemists here?


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"When you get the message, hang up the phone." - Alan Watts

We Die to Remember What We Live to Forget


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Offlinestemmer
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Re: Pupil Dilation [Re: Around In Circles]
    #5253763 - 02/02/06 12:04 AM (18 years, 4 hours ago)

A chemist wont know any more about brain functions than anyone else. Are you just kidding or something. Or no, lets ask a rocket scientist why psilocybin makes peoples eyes dialate.
I seem to have answered your question to some extent. So DOnt discredit me for giving you good info, a place to start.
You do know that it is not just the psilocybin that makes your eyes dialate?
I did the best I could while doing a 20 second google search.
You are basically asking people to tell you why psilocybin does things to other brain functions and which ones.(and in what order?)
Come on dude, im throwing you a bone here. Dont get too snotty.
All of those chemicals are in direct relation to one another.
Your question asks, (can you show me the life cycle)?
SO, look it up dude, if your going to get snotty.


Edited by stemmer (02/02/06 12:21 AM)


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OfflineWillieTomg
If stemmer votedme 1, I'm doingSOMETHING right!
Registered: 04/09/05
Posts: 425
Loc: On the insides of your ey...
Last seen: 11 years, 3 months
Re: Pupil Dilation [Re: stemmer]
    #5254338 - 02/02/06 08:34 AM (17 years, 11 months ago)

Quote:

Pupil dialation is a sign of brain damage.




Not the best way to introduce your post, since that statement includes people who've been to the optometrist and insomniacs.

But provided stemmer gave information from a reputable source, I'd have to guess the endorphin/dopamine combination released during the rush of a trip makes your eyes big.

Unless you want the SPECIFIC chemical reactions that trigger pupil dilation. That's a little beyond my area of expertise.

P.S. stemmer, chill the hell out man, he's not being snotty, he's being curious. It's not exactly information that one can find out in his/her local library. There's a lot of bullshit to sift through on the internet (demonstrated by your copy-pasting a million answers beyond the question he asked) and he thought that a place called THE SHROOMERY could answer a question about one of the effects of *slaps forehead* hallucinogenic mushrooms!


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Battles of wits are impossible with the unarmed.


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Invisiblebadchad
Mad Scientist

Registered: 03/02/05
Posts: 13,372
Re: Pupil Dilation [Re: WillieTomg]
    #5254497 - 02/02/06 09:45 AM (17 years, 11 months ago)

Pupil dilation is a normal aspect of sympathetic nervous system stimulation (think "fight or flight"). It is a normal physiological process, and not indicative of brain damage.

We don't know the exact mechanism of action of hallucinogens, or what causes hallucinations. Therefore we can only speculate as to "why" dilation occurs with some hallucinogens.


--------------------
...the whole experience is (and is as) a profound piece of knowledge.  It is an indellible experience; it is forever known.  I have known myself in a way I doubt I would have ever occurred except as it did.

Smith, P.  Bull. Menninger Clinic (1959) 23:20-27; p. 27.

...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.

Osmond, H.  Annals, NY Acad Science (1957) 66:418-434; p.436


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OfflineAround In Circles
Eternally Recurring

Registered: 01/29/06 Happy 18th Shroomiversary!
Posts: 1,118
Last seen: 14 hours, 13 minutes
Re: Pupil Dilation [Re: badchad]
    #5261873 - 02/04/06 08:24 AM (17 years, 11 months ago)

Quote:

badchad said:
Pupil dilation is a normal aspect of sympathetic nervous system stimulation (think "fight or flight").  It is a normal physiological process, and not indicative of brain damage.

We don't know the exact mechanism of action of hallucinogens, or what causes hallucinations.  Therefore we can only speculate as to "why" dilation occurs with some hallucinogens.





Thank you very much  :thumbup:


--------------------
"When you get the message, hang up the phone." - Alan Watts

We Die to Remember What We Live to Forget


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OfflineiDeving
Stranger
Registered: 12/11/11
Posts: 1
Last seen: 12 years, 1 month
Re: Pupil Dilation [Re: Around In Circles]
    #15499649 - 12/11/11 12:15 PM (12 years, 1 month ago)

actually this may answer ur question:

proparacaine: numbs the nerves in eye that stimulate the pupil depending on brightness/state.

this probably is the simplest explanation of why most peoples eyes pupils get large during trips. it simply numbs the nerves.. through what i do not know.


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