|
Some of these posts are very old and might contain outdated information. You may wish to search for newer posts instead.
|
Gratos
Just thinkin anddrinkin

Registered: 08/21/05
Posts: 1,374
|
Re: LSD from Lysergic Acid Amides [Re: Koala Koolio]
#5248860 - 01/31/06 09:29 PM (18 years, 4 hours ago) |
|
|
Quote:
elgr said: "I beleive I heard somewhere that Hoffman's laboratory notes have all been quietly edited, which may have been to keep the synth more of a secret. "
Sounds like bullshit. Any source at all?
Why would he keep it a secret. He's still alive, there are tons of other synths, and as far as I'm aware, he has nothing against the production of acid, heh. I heard his most recent dose was a couple years ago... unless he did it in celebration of the symposium or his birthday.
Although Ive never made a 'hard and heavy' effort to to find a copy Ive also been told that its almost impossible to find the Hoffman Papers. Then again why wouldnt he have rewritten them? Who knows, I certainly dont.
Edited by Gratos (01/31/06 09:30 PM)
|
Koala Koolio
TTAGGGTTAGGGTTAGGGTTAGGG

Registered: 01/07/04
Posts: 7,752
|
Re: LSD from Lysergic Acid Amides [Re: Gratos]
#5249087 - 01/31/06 10:13 PM (18 years, 4 hours ago) |
|
|
I could've sworn I read about some huge project to archive and backup all the documents sandoz has had over the years. Was this one an exception?
Yes, I'm aware of the understatement. I'd hoped it would illustrate my point.
-------------------- You're not like the others. You like the same things I do. Wax paper, boiled football leather... dog breath. We're not hitch-hiking anymore, we're riding!
|
Asante
Mage


Registered: 02/06/02
Posts: 86,792
|
Re: LSD from Lysergic Acid Amides [Re: Koala Koolio]
#5249898 - 02/01/06 01:32 AM (18 years, 50 minutes ago) |
|
|
Hofmann used the azide process.
R-CO-NH-R' + H2N-NH2 --> (iso)R-CO-NH-NH2 (iso)R-CO-NH-NH2 + HO-N=O --> (iso)R-CO-N3 (iso)R-CO-N3 + HN(CH2CH3)2 --> (iso)LSD (iso)LSD --alkali--> LSD
It is much more complicated than it should be and uses almost nothing but problematic chemicals and has losses due to side-reactions. A hifmann-synth lab is far more likely to blow up than a meth lab, thats just one of the reasons its never done anymore.
Shulgin uses the POCl3 route which is far cleaner and more convenient. There is no "magic" in the Hofmann synth except nostalgia.
-------------------- Omnicyclion.org higher knowledge starts here
|
moecat
Visitor
Registered: 02/19/05
Posts: 93
|
Re: LSD from Lysergic Acid Amides [Re: Gratos]
#5251944 - 02/01/06 05:00 PM (17 years, 11 months ago) |
|
|
makes sense
Edited by moecat (01/01/07 11:17 PM)
|
|