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Offlinepedxing
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Registered: 01/17/02
Posts: 4
Last seen: 13 years, 8 months
AMT as substrate enhancement>?
    #523118 - 01/17/02 04:04 AM (15 years, 1 month ago)

I have seen plenty of discusion concerning using tryptamine as an additive to the substate for increased psylocin potency. I am hoping to bend the ear of someone who is more knowledgeable with the chemistry involved than I. would it be possible to use AMT in the substrate instead of Tryptamine HCL as per this method? (http://www.shroomery.org/findorgrowthem/tryptaminecubensis.html)

It appears that the fungus simply attaches a 4-hydroxy group to any triptamine that is available to it. (http://www.shroomery.org/forums/showflat.php?Cat=&Board=Forum4&Number=318393&page=&view=&sb=&o=&fpart=all&vc=1)

Is this correct? would 4-hydroxy alpha-methyltryptamine be the resultant chemical instead of (and maybe in addition to) the 4-hydroxy dimethyltriptamine (psylocin)? is there anything known about the effects of 4-hydroxy alpha-methyltryptamine?

I would welcome any insights, thoughts, and certainly facts related. thank you.


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InvisibleMajortrippz
enthusiast
Registered: 06/19/01
Posts: 199
Re: AMT as substrate enhancement>? *DELETED* [Re: pedxing]
    #523394 - 01/17/02 11:47 AM (15 years, 1 month ago)

Post deleted by Majortrippz

Reason for deletion: I didn't post this my account must have been hacked.



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Offlinepedxing
Stranger
Registered: 01/17/02
Posts: 4
Last seen: 13 years, 8 months
Re: AMT as substrate enhancement>? [Re: Majortrippz]
    #523443 - 01/17/02 01:18 PM (15 years, 1 month ago)

I've found a short reference to 4-hydroxy a-mt at Tihkal. (http://www.erowid.org/library/books_online/tihkal/tihkal48.shtml)

Here's the part regarding 4-hydroxy a-mt: "There is some interesting biochemistry and pharmacology all around the edges of a-MT. The 4-hydroxy analogue of a-MT has been looked at in human subjects. It is reported to be markedly visual in its effects, with some subjects reporting dizziness and a depressed feeling. There were, however, several toxic signs at doses of 15 to 20 milligrams orally, including abdominal pain, tachycardia, increased blood pressure and, with several people, headache and diarrhea."

Since the amount I would consider using would be 16-25 miligrams per cake I don't imagine the toxic signs would present themselves. the combination of 4-hydroxy a-mt and psylocin would be incredibly synergistic.



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Offlinegray1
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Registered: 04/30/01
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Last seen: 14 years, 10 months
Re: AMT as substrate enhancement>? [Re: pedxing]
    #523458 - 01/17/02 01:30 PM (15 years, 1 month ago)

the toxicity of humans and mushrooms to amt most likely will be vastly different, the last reply was suggesting that that level of amt could hinder the fungus growth.
will it? only one way to find out, so give it a try, however, it may or may not increase the amount of psilocin/psilocybin, or other end product tryptamines/indole alkaloids.
several tryptamines have been proposed as suplements because they would introduce precursors that are furthre down the biosynthetic pathway to psiolcybin/psilocin, however, the fungus may not be able to 1.: uptake the chemical from the growth media (this has been shown for several tryptamines, and there are threads about it, search somee more) and 2: actually modify the chemical if and when it gets into the organism.

if you're looking for synergistic activity, just taken them at the same time from different sources, especially as research chemicals are not particularly cheap and suited for substrate suplements...


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Offlinejihead
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Registered: 06/09/00
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Re: AMT as substrate enhancement>? [Re: pedxing]
    #523689 - 01/17/02 07:10 PM (15 years, 1 month ago)

look, if your gunna waste the amt, you might as well send it to me so i can just eat the shit. j/k


--------------------
kill white noise


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OfflineDarK_SavioR
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Registered: 05/06/01
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Last seen: 14 years, 9 months
Re: AMT as substrate enhancement>? [Re: pedxing]
    #527664 - 01/21/02 10:32 PM (15 years, 1 month ago)

I'm thinking you'd get more from the amt by itself than you would adding it to your substrate. Then again if you have the money or amt to use for it, try it.


--------------------
Vitamin C chase, kill the taste. You can tell its nasty by the look on my face.
Ralphster44 & The FSR!
All thats stated above is for humor and a lie!!


Edited by DarK_SavioR (01/22/02 01:15 AM)


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Invisiblespores
haploid
 User Gallery

Registered: 02/19/99
Posts: 2,483
Loc: Washington
Re: AMT as substrate enhancement>? [Re: pedxing]
    #527724 - 01/21/02 11:51 PM (15 years, 1 month ago)

Mods, edit that post. Dark_Savior, read the supplier policy dude, don't go pasting that shit everywhere http://www.shroomery.org/suppliers.html .

DH


Edited by DethHed (01/21/02 11:52 PM)


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OfflineDarK_SavioR
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Registered: 05/06/01
Posts: 454
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Last seen: 14 years, 9 months
Re: AMT as substrate enhancement>? [Re: spores]
    #527788 - 01/22/02 01:15 AM (15 years, 1 month ago)

my bad dethhed


--------------------
Vitamin C chase, kill the taste. You can tell its nasty by the look on my face.
Ralphster44 & The FSR!
All thats stated above is for humor and a lie!!


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