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Mushrooms, Mycology and Psychedelics > Advanced Mycology
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Chemistry Question
    #488856 -

Ok, I dabble in a little organic chemistry, and I am aware of several synthetic routes to shrooms akaloids, but my main question is, how the hell does a shroom do it?

How the hell does it even form even an indole ring with nutrients water and air?

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Re: Chemistry Question [Re: psilocybian]
    #488970 -

Check out this link. From there it is futher processed into the good stuff.


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"The greatest enemy of knowledge is not ignorance, it is the illusion of knowledge." -Stephen Hawking

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Re: Chemistry Question [Re: Humidity]
    #489795 -

WOOF! The shrooms goes through a lot just to even make tryptophan.

I was thinking that since shrooms made these compounds from basic materials, someone might be able to replicate that in a laboratory. But forget it, I'd rather stick to starting with IAA or tryptophan any day.

I am still interested though. Even though your link gave the reaction mechanisms, it doesn't provide any details. Got any more links?

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Re: Chemistry Question [Re: psilocybian]
    #489879 -

There are synthetic ways to make psilocin, but you will need a laboratory to do it. And you will need to become a chemist because if you don't know what you are doing you are going to either blow yourself up or kill someone with a chemical that you make that is not psilocin. Leave to work up to the fungus they are the greatest chemists of them all.


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_____________________________________________________________________________________
"The greatest enemy of knowledge is not ignorance, it is the illusion of knowledge." -Stephen Hawking

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Re: Chemistry Question [Re: Humidity]
    #494921 -

for sure, not only is nature a better chemist for somehting like that, but it's also a lot cheaper to let that nature take its course than to try to make l_tryptophan yourself

i've known of ppl who even with their own labs and lots of experience, have had to waste a lot of money (thousands) b4 the finished product was achieved.

think of it this way, gardenin is easier than chemistry, thus a large grow room is more feasable (and easier to conceal) than a small lab. not to mention the equipment required is 100x cheaper and easier to obtain and no funny questions

let us focus on the casings :)

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Re: Chemistry Question [Re: aka]
    #495042 -

you might as well make lsd or pcp hell of a lot cheaper not to mention easier


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I have only been wrong one time in my life.
thats when i thought i was wrong.
If its not a rave its not a party

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Re: Chemistry Question [Re: biggwigg]
    #495132 -

Much organic chemistry is complicated and dangerous. The synthesis of psilocybin is especially hard, since it is 4-substituted and has that free hydroxyl group there.

It is basically DMT with the 4-OH, but DMT is two steps from a common precursor, psilocybin is at least six, and the precursor ain't that common. Better to let the mushroom do the work for you.

But if you are still interested in the theory, try "Improvements to the Synthesis of Psilocybin
and a Facile Method for Preparing the O-Acetyl Prodrug of Psilocin" by David E. Nichols and Stewart Frescas; Synthesis No. 6, 935-938 (1999)

- AE


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Mushrooms, Mycology and Psychedelics > Advanced Mycology
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