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Learyfan
It's the psychedelic movement!



Registered: 04/20/01
Posts: 34,333
Loc: High pride!
Last seen: 6 hours, 28 minutes
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Re: The Lemon Experience... [now a community experiment - please contribute] [Re: KinichAhau]
#12753198 - 06/16/10 03:31 PM (14 years, 14 days ago) |
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We're assuming it's 28 wet grams.
-------------------- -------------------------------- Mp3 of the month: Sons Of Adam - Feathered Fish
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KinichAhau
Sun Eyed Lord



Registered: 12/07/09
Posts: 862
Loc: State of Eternity
Last seen: 13 years, 5 months
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Re: The Lemon Experience... [now a community experiment - please contribute] [Re: Learyfan]
#12753244 - 06/16/10 03:38 PM (14 years, 14 days ago) |
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Quote:
Learyfan said: We're assuming it's 28 wet grams.
I forgot to write wet....*Sigh* Yes, it was wet. A 28g dry trip with ATL#7 would be INSANE. And not the good kind either. The lose-my-shit-turn-crazy kind.
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(Thanks to Sui for letting me use this!) "....buy small portions of say 1/2 gram...buy from a reliable internet source (they're out there) and store in a cool, dark, secret place"
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ibetitsagoldenrock
Stranger

Registered: 06/16/10
Posts: 1
Loc: North Carolina
Last seen: 14 years, 14 days
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Re: I may have discovered something... [Re: KinichAhau]
#12753467 - 06/16/10 04:23 PM (14 years, 14 days ago) |
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I had some mushroom capsules (approx: 2.5g) which I emptied into a large glass of orange juice/lemon juice mix (approx: 20oz and the juice from 1.5 lemons). I consumed the mixture and within 10 minutes began to notice that time was elongating heavily and within 15 minutes there were significant CEVs and by 25 minutes perceptible OEVs. I reached the plateau approximately 10 minutes after that and remained there for about two and a half hours. 5 hours after consuming the mushrooms I was completely "sober." Over the course of the trip itself I consumed 12oz of water, half of a pack of Camels, and approximately 1.25 of a gram of pot.(My friend and I were sharing a 2.5g bag).
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Doin that rag
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grischnackh
Registered: 11/29/09
Posts: 238
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Post deleted by grischnackhReason for deletion: /
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EntheogenicPeace
Scholar



Registered: 10/04/05
Posts: 3,926
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Re: I may have discovered something... [Re: grischnackh]
#12774074 - 06/20/10 03:06 PM (14 years, 10 days ago) |
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I think it's been suggested that the acidity of the lemon concentrate dephosphorylates the psilocybin to psilocin (the active form), which would also occur in the stomach. Perhaps increasing the surface area by breaking/grinding up the mushrooms, along with 5-15 min. of soaking/stirring in the lemon concentrate, results in a greater conversion %... whereas otherwise more unconverted psilocybin would pass through the stomach into the GI tract & not be effect for psychoactive intents. The comment(s) of someone who understands this biology/biochemistry better than myself would be appreciated.
-------------------- --- nothing right now ---
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Dinosaurr
Stranger

Registered: 01/01/10
Posts: 65
Last seen: 10 years, 2 months
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Quote:
EntheogenicPeace said: I think it's been suggested that the acidity of the lemon concentrate dephosphorylates the psilocybin to psilocin (the active form), which would also occur in the stomach. Perhaps increasing the surface area by breaking/grinding up the mushrooms, along with 5-15 min. of soaking/stirring in the lemon concentrate, results in a greater conversion %... whereas otherwise more unconverted psilocybin would pass through the stomach into the GI tract & not be effect for psychoactive intents. The comment(s) of someone who understands this biology/biochemistry better than myself would be appreciated.
Then, would dilute HCl(aq) do the same thing? I understand HCl isn't something you would normally want to be drinking....but I don't imagine if diluted to the same point as stomach acid it would be about the same as swallowing vomit.
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EntheogenicPeace
Scholar



Registered: 10/04/05
Posts: 3,926
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Re: I may have discovered something... [Re: Dinosaurr]
#12774909 - 06/20/10 05:51 PM (14 years, 10 days ago) |
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Stomach acid is largely HCl, pH a little under 2 I believe (whereas lemon concentrate is 2.5-3, i think.) You absolutely would not want to drink that strong of HCl; it would wreak havoc on your mouth & esophagus, & could kill you. You wouldn't want to consume HCl at any concentration.
http://www.jtbaker.com/msds/englishhtml/h3883.htm
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ServantOfBaphomet
StarKitten's Boyfriend


Registered: 10/14/09
Posts: 2,986
Loc: αßπΣσµτΦΘΩδ∞
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Re: I may have discovered something... [Re: Dinosaurr]
#12774953 - 06/20/10 06:03 PM (14 years, 10 days ago) |
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Quote:
Dinosaurr said:
Quote:
EntheogenicPeace said: I think it's been suggested that the acidity of the lemon concentrate dephosphorylates the psilocybin to psilocin (the active form), which would also occur in the stomach. Perhaps increasing the surface area by breaking/grinding up the mushrooms, along with 5-15 min. of soaking/stirring in the lemon concentrate, results in a greater conversion %... whereas otherwise more unconverted psilocybin would pass through the stomach into the GI tract & not be effect for psychoactive intents. The comment(s) of someone who understands this biology/biochemistry better than myself would be appreciated.
Then, would dilute HCl(aq) do the same thing? I understand HCl isn't something you would normally want to be drinking....but I don't imagine if diluted to the same point as stomach acid it would be about the same as swallowing vomit.
What you have in your stomach is not just diluted HCl. It's made a certain way that's safe to your stomach..
Quote:
Chloride (Cl−) and hydrogen (H+) ions are secreted separately in the stomach fundus region at the top of the stomach by parietal cells of the gastric mucosa into a secretory network called canaliculi before it enters the stomach lumen.[19]
So the stomach actually makes the HCl in itself in such a way to only be in the only very small area of your body that can withstand it. If you drank any HCl, even extremely diluted, it would burn your throat and esophagus all to fuck.
-------------------- Do what thou Wilt shall be the Whole of the Law Love is the Law. Love under Will
Hail Eris! All Hail Discordia!! The Sovereign Peanut has Spoken!!
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smoke dank



Registered: 01/02/10
Posts: 390
Last seen: 12 years, 11 months
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Re: The Lemon Experience... [now a community experiment - please contribute] [Re: KinichAhau]
#12774999 - 06/20/10 06:12 PM (14 years, 10 days ago) |
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Quote:
KinichAhau said:
Quote:
Learyfan said: We're assuming it's 28 wet grams.
I forgot to write wet....*Sigh* Yes, it was wet. A 28g dry trip with ATL#7 would be INSANE. And not the good kind either. The lose-my-shit-turn-crazy kind.
I'd go for it if it was free.
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Povlovich
Stranger


Registered: 11/10/09
Posts: 140
Loc: Ohio
Last seen: 13 years, 11 months
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Re: The Lemon Experience... [now a community experiment - please contribute] [Re: Underhillmaster]
#12775305 - 06/20/10 07:11 PM (14 years, 10 days ago) |
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# What liquid are you using?
Lemon juice
. # How much liquid did you drink the powder with? (oz)
Probably around 5 oz.
. # Time to "first alert" (aka, "whoa, something's definitely going to happen")
20 minutes
. # Time to onset of visual disturbance
40-50 minutes
. # Time to peak (rough estimate)
An hour to an hour and 20 minutes
. # Time to first sign of diminishing effects
3-4 hours after ingestion
. # Time to baseline (indiscernable effects)
6 hours
-------------------- The Three Yellow Men have arrived.
Edited by Povlovich (06/20/10 07:12 PM)
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Shad0w
In trouble again.


Registered: 06/08/08
Posts: 3,639
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Re: The Lemon Experience... [now a community experiment - please contribute] [Re: Povlovich]
#12776597 - 06/21/10 12:01 AM (14 years, 9 days ago) |
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EntheogenicPeace
ServantOfBaphomet
Saving lives. 
Good job.
-------------------- Nothing I write on Shroomery's message boards or in private messages are true. I am fucking crazy and I make all this shit up because I can. [quote]sploogepanz55 said: ^^^ haha what a bummer, shad0w. All this talk about dying. [/quote] [quote]psychoanomaly said: And so, I feel your intolerance and phobia towards rectal administration of psychedelics is a violation of the music of the spheres [/quote] [quote]shroom_sandwich said: I could have sworn I seen a thread about a guy saying his dog killed the neighbors chickens earlier....[/quote]
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grischnackh
Registered: 11/29/09
Posts: 238
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Post deleted by grischnackhReason for deletion: /
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leet
Stranger

Registered: 01/18/10
Posts: 23
Last seen: 13 years, 1 month
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Re: I may have discovered something... [Re: grischnackh]
#12783154 - 06/22/10 06:42 AM (14 years, 8 days ago) |
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Wow, it all makes sense now.
A few weeks ago I decided to eat just a few shrooms to get a little messed up but nothing to crazy. I was also drinking at that time a significant amount of a mixed drink I made with pineapple & cranberry juice and vodka.
It knocked me on my ass. I was so confused why I was tripping so hard from such a small dose. I was literally like the OP, on the floor, incapable of thinking in english & completely out of it. I dunno wtf happened but it was pretty nuts.
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Hewbz
Fool


Registered: 06/14/10
Posts: 6
Last seen: 13 years, 3 months
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Re: I may have discovered something... [Re: leet]
#12785265 - 06/22/10 03:21 PM (14 years, 8 days ago) |
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Wow, this all sounds crazy. Me and 2 of my mates are picking up an 8th of shrooms soon and are thinking about trying this technique but splitting it 3 ways and seeing if we get somewhat strong effects. Anyone think this might work? ? we will be using lemon
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Johnny Depp

Registered: 04/01/10
Posts: 2,201
Last seen: 9 years, 2 months
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Re: I may have discovered something... [Re: Hewbz]
#12785414 - 06/22/10 03:43 PM (14 years, 8 days ago) |
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.
Edited by Johnny Depp (12/19/14 02:29 AM)
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EntheogenicPeace
Scholar



Registered: 10/04/05
Posts: 3,926
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Re: I may have discovered something... [Re: Johnny Depp]
#12848414 - 07/04/10 04:57 PM (13 years, 11 months ago) |
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A few friends (3, to be exact) recently split an 1/8 between them & were on a porch out in the country & watched a thunderstorm off in the distance... said it was amazing. Point being that depending on circumstance, an 1/8 can be split 3 ways for a desirable effect, particularly if one isn't necessarily looking to trip really hard, but rather just a mellow (yet still beautiful)experience.
-------------------- --- nothing right now ---
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EntheogenicPeace
Scholar



Registered: 10/04/05
Posts: 3,926
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Re: I may have discovered something... [Re: grischnackh]
#12848431 - 07/04/10 05:03 PM (13 years, 11 months ago) |
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Quote:
I still think the basic thing would be worth a try if someone is game enough. I believe that both acid and basic conditions can cause dephosphorylation.
I'm not a chem expert, but i would need to see a source before accepting this. I don't see an excess of negatively charged OHs floating around in solution interacting with the negative charge on the phosphate group. Not saying it can't happen, but i'd be curious the rxn mechanism if it did.
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grischnackh
Registered: 11/29/09
Posts: 238
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Re: I may have discovered something... *DELETED* [Re: EntheogenicPeace]
#12850508 - 07/05/10 04:21 AM (13 years, 11 months ago) |
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Post deleted by grischnackhReason for deletion: /
Edited by grischnackh (07/05/10 05:46 AM)
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EntheogenicPeace
Scholar



Registered: 10/04/05
Posts: 3,926
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Re: I may have discovered something... [Re: grischnackh]
#12851792 - 07/05/10 01:00 PM (13 years, 11 months ago) |
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That's interesting. From the abstract of the article, it suggests the the conversion occurs somewhere other, further along, than the stomach. If so, then the soak in lemon concentrate would seem to be irrelevant if it is an enzyme that operates at physiological pH that does it.
As for which soak, in acidic or basic conditions, causes the dephosphorylation, either at all or to what extent, that would be nice to know (didn't intuitively think about the possibility of nucleophilic attack at the P being an option, but I guess if the hydroxyl could maneuver its way in amid all the O atoms, or maybe at the adjacent C in the ring structure...) I wonder if someone has done it? The lab I work at has a photospectrometer designed to read small volumes of solution (typically we use 1.0 uL.)
It wouldn't be terribly hard to set-up & do an exp. to determine starting & end concentrations of both molecules in each type of treatment, as long as one had a good way to isolate the molecules (selective precipitation after appropriate centrifugation has been done... unless the concentration of other small biomolecules relative to the two of interest would be insignificant, so that the absorbance peak(s) are easy to distinguish from among any background static?) from everything else in there.
Hell, maybe I'll look into that sometime later this year if I'm able to make some free time for it. Any advice, ideas, or (most potentially time-saving) links to articles where someone has already done this? The mechanism would be worthwhile to learn... unless we've all been had by psychology/a placebo effect?
P.S. If a mechanism has been cited & properly sourced already in one of the (many) pages prior & someone recalls it, please refresh it. Thanks.
-------------------- --- nothing right now ---
Edited by EntheogenicPeace (07/05/10 01:11 PM)
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grischnackh
Registered: 11/29/09
Posts: 238
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Re: I may have discovered something... *DELETED* [Re: EntheogenicPeace]
#12855202 - 07/06/10 05:35 AM (13 years, 11 months ago) |
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Post deleted by grischnackhReason for deletion: /
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