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InvisibleApOcaLyPSe_1985
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Growing cubensis on a bed of Salvia leaves?
    #4356543 - 06/30/05 06:07 PM (18 years, 8 months ago)

Hey all,

I'm not really into growing shrooms but I know my biology. Mushrooms like to grow on rotting material in humid environments. So what would happen if you would replace the rotting material with Salvia leaves? I guess it would feed on it but I don't know if it would absorb and hold the psychedelic content of the Salvia leaves. If that would work then you would get killer shrooms with added Salvia potency! Great shit in my opinion if this would work :laugh:

So what do you think about it?

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Offlinejben
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Re: Growing cubensis on a bed of Salvia leaves? [Re: ApOcaLyPSe_1985]
    #4357410 - 06/30/05 10:35 PM (18 years, 8 months ago)

hahahahahaha. you wish man. no the mushrooms would not gain the power of the salvia. but i wish in real life that would happen. you could make some crazy ass superdrugs. add some dead peyote, a pinch of any dmt bearing plants. and bam!


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InvisibleCaptainH13
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Re: Growing cubensis on a bed of Salvia leaves? [Re: jben]
    #4358539 - 07/01/05 05:08 AM (18 years, 8 months ago)

that just made my morning......
:grin:


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Offlineliveby
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Re: Growing cubensis on a bed of Salvia leaves? [Re: CaptainH13]
    #4358544 - 07/01/05 05:17 AM (18 years, 8 months ago)

it wont work , i can go into detail but yeah


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OfflinePsiloman
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Re: Growing cubensis on a bed of Salvia leaves? [Re: ApOcaLyPSe_1985]
    #4359022 - 07/01/05 10:08 AM (18 years, 8 months ago)

Quote:

ApOcaLyPSe_1985 said:
Hey all,

I'm not really into growing shrooms but I know my biology. Mushrooms like to grow on rotting material in humid environments. So what would happen if you would replace the rotting material with Salvia leaves? I guess it would feed on it but I don't know if it would absorb and hold the psychedelic content of the Salvia leaves. If that would work then you would get killer shrooms with added Salvia potency! Great shit in my opinion if this would work :laugh:

So what do you think about it?




You know your Biology? Ok,lets take that as granded for now.

So

a)Do you know what is the salvia divinorum active principle and in which chemical family it belongs?
b)How do you know that 1) it will be uptaken by the mushroom 2) it WONT be modified or digested?
c)Are you familiar with the pharmacology of Salvia divinorum's active principle and the comments on its per os use and absorption?

"Knowing your biology" is a heavy title to bear and in order to bear it succesfully it must be defended and backep up with knowledge and research! The questions above are to be used as a selftest for you.If you find trouble answering any of them ,then that means that more research is required.

Tip: When setting on an idea and on a new project please investigate all parts of it.It may appear like a great idea at first but if you go to sagewisdom website and study on salvia and then study on the shroomery and other sites you may find a dozen of reasons on why it wuld work

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Offlinejben
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Re: Growing cubensis on a bed of Salvia leaves? [Re: Psiloman]
    #4359189 - 07/01/05 11:03 AM (18 years, 8 months ago)

haha. this is one funny thread. psiloman, do you mean "why it wont work" instead of wuld? because that would make more sense to me.


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OfflineChemical_Bliss
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Re: Growing cubensis on a bed of Salvia leaves? [Re: Psiloman]
    #4359193 - 07/01/05 11:04 AM (18 years, 8 months ago)

Very wise words psilo.

And as to "adding a pinch of dmt containt plants?"

According to Shulgin this should work. This subject is widely debated in other forums....heres a good start though

http://www.erowid.org/library/books_online/tihkal/tihkal16.shtml

Hope this helps.


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Offlinebutterflydawn
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Re: Growing cubensis on a bed of Salvia leaves? [Re: ApOcaLyPSe_1985]
    #4359258 - 07/01/05 11:22 AM (18 years, 8 months ago)

nah,
not a good idea buddy


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Offlinejben
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Re: Growing cubensis on a bed of Salvia leaves? [Re: butterflydawn]
    #4359269 - 07/01/05 11:27 AM (18 years, 8 months ago)

chemical bliss, nice thread. seems like it makes sense i suppose since psilocybin and dmt are structurally similar.


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OfflinePsiloman
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Re: Growing cubensis on a bed of Salvia leaves? [Re: jben]
    #4359285 - 07/01/05 11:34 AM (18 years, 8 months ago)

Quote:

jben said:
haha. this is one funny thread. psiloman, do you mean "why it wont work" instead of wuld? because that would make more sense to me.




Correct.i meant "why it wont work".

Let me also give a "spoiler" to the selftest: If we take for granded that the mushrooms will succesfully grow on the leaves, that the active princible will be uptaken by the mushroom,and undigested and unmodified would concentrate itself on the fruitbodies,then we still have a very very big hurdle infront of us.That is the bioavailability of per os use! (Per os = ingestion,by mouth and absorbed by GI track for those not good on Latin and Pharmacology)

In short ,yes it WOULD NOT work.WHat i want though is this person answering the question for hismelf as well..I could answer this question as well as many others ,not because we are wise sages or we came out of our mother's womb with "Encyclopedia of Psychoactive plants" and a CD archive of erowid stappled on our willies (or labia if female!) ,but because we took time learning and investigarting each part ,because we are simply interested at them.

Hmmm..i wonder,should we compose a "How to Research" guide giving tips ,methods,credible sources (govermental and private) as well as tips on how to think around a problem? It may sound like "it goes without saying how to research" for someone with academic studies on a science or to the passionate amateur but it doesnt go without saying for all people.

By the way,adding DMT would propably be metabolised to Psilocin,i dont know if psilocybin would rise.Also the 4-OH (or 4-HO more corectly structurally) substitutuion would happen to most TRYPTAMINES added to the substrate. "Put TryptamineMickeyMouse in ,get 4-HO-TryptamineMickeyMouse out"

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OfflineChemical_Bliss
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Re: Growing cubensis on a bed of Salvia leaves? [Re: Psiloman]
    #4359733 - 07/01/05 01:38 PM (18 years, 8 months ago)

Correct.

I think a how to research guide is an awesome idea. Even if we could convince to use the search engine more often as most of these questions have been asked before (not saying this one has)

And on the subject of adding tryptamines to substrates I think I remember reading that even AMT added to mushroom growing substrate can add a certain amount of potency. I`ll see if I can find some info on this.

I wonder if mush could be grown on P. Harmala? Would that add the MAOI properties directly into the mushrooms? I admit my chemistry knowledge is very limited but could it possibly yeild a 4-HO MAOI that might be active? Sorry if this is a stupid question :smile:


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OfflinePsiloman
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Re: Growing cubensis on a bed of Salvia leaves? [Re: Chemical_Bliss]
    #4360749 - 07/01/05 06:04 PM (18 years, 8 months ago)

Hmmm...Same principles hold here more or less although a beta carboline (hmmm could be think of it as a tricyclic tryptamine?) looks slightly like a better candidate. FIrst and foremost check if on harmine or harmaline the 3 ,4 and/or 5 positions are substituted,if they are i dont know if the enzyme can "hit" the 4th position.If it is substituted there,maybe another enzyme can convert it still to something else? Keep in mind that most of enzymes are veeeeery whimy specific lil buggers! They dont sleep around with substrates,they are quite faithfull keeping it to the family! Heh,that is chemical family in not individual!

Some worries about it besides absorption:

1)Will harmine and harmaline have antifungal properties? I have heard its an antihelmetic since it blokes the cytochrome part of MAO enzyme (correct me if im wrong) and could be antibacterial as well. We certainly dont want the mitochondrial of our fungal friends to suffer do we?

2)Will it fit in the enzyme's active center? I dont know how the enzyme binds on it and i wonder if that "third ring" ,since its "fixed: position rather than a movable single bond chain, could get in the way of the enzyme.

One could either summon a shulgin with a proteomics/enzyme specialist to answer that or try the experiment and maybe try a half assed paper chromatography compared to a normal Psilocybe mushrooms chromatography under black light.Yes,its ghetto style,if any extra bands appear on the experimental sample one could cut em off ,put it in appropriate solvent to dissolve and send it allong with a sample of the solvent for proper chromatography that can ID the compound...

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OfflineChemical_Bliss
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Re: Growing cubensis on a bed of Salvia leaves? [Re: Psiloman]
    #4362895 - 07/02/05 11:32 AM (18 years, 8 months ago)

Wow! Psilo I wish I had half of your knowledge on such things. A bit of that is over my head but I get what you are trying to say. Thanks for the info...Ill look further into this.


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InvisibleApOcaLyPSe_1985
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Registered: 02/19/05
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Re: Growing cubensis on a bed of Salvia leaves? [Re: Chemical_Bliss]
    #4362966 - 07/02/05 12:03 PM (18 years, 8 months ago)

hey there. thanks for all the replies, i really thought it would be simple. with "knowing my biology" i meant the basics :p
seems things are alot more difficult then my knowledge can handle.

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OfflinePsiloman
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Re: Growing cubensis on a bed of Salvia leaves? [Re: ApOcaLyPSe_1985]
    #4363070 - 07/02/05 12:53 PM (18 years, 8 months ago)

Quote:

Wow! Psilo I wish I had half of your knowledge on such things




Quote:

seems things are alot more difficult then my knowledge can handle.




Give me knowledge and sooner or later it will be outdated! Give me willpower and then i can acquire the research skills to procure knowledge!

That is my moto! If one feels lacking in knowledge one can top it up pretty easily.Ok ,i had a headstart because i had academical studies on Biological Sciences ,but apart from the basic knowledge it gave me ,the best gift was the research skills that are the ones that remain.I may forget half of my biology in 10 years time,but my research skills can help me update it! They have only one prerequisite: Willpower! Intelligence helps,but its secondary,simply put an intelligent person will need 5 minutes to understand a very difficult concept whereas the "not so bright one" will need lets say half an hour.No big deal! Both of them though would get nothing if they dont try.

Speaking of chromatography,here are the principles:

http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/C/Chromatography_paper.html

http://www.agsci.ubc.ca/fnh/courses/food302/chromato/schromato03.htm

(Usually university pages and affiliated with them pages is what you are looking for ,for up to date knowledge)

Ok,the "grow them on harmala" part would be easy for a mushroom grower if indeed they can grow in presence of beta carbolines.Once an crude extraction of the biomass is made (even mixing their juice with some acid,like HCl or citric) it can be subjected to chromatography. Have you noticed how an absorbant tissue draws up water in contact? you can experiment with it at home by getting some absorband tissue droping on it 1 drop of lets say 2 different inks on two places and on the third place drop half a drop of each ink together.Wet it as the links show and in some hours you will see the spots migrating on the paper and the inks on the third drop being seperated! You might even find out that the two different unmixed inks are made up by two or three other colorful compounds!

Ok,thats a home experiment for kicks and laughs,but paper chromatography is not expensive and you can get equipment from many places for it,cheap and no questions asked!

Well,my point is that even a fancy sounding method could be well in your reach if you have the willpower for it! Ok,dont expect cold fusion in a mason jar,but chromatography is doable!

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OfflineChemical_Bliss
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Re: Growing cubensis on a bed of Salvia leaves? [Re: Psiloman]
    #4369123 - 07/04/05 10:33 AM (18 years, 8 months ago)

Psilo your my hero when I grow up I wanna be just like you :smile:.

And you absolutley right, I think I`ll spend the rest of the afternoon brushing up on my chemistry knowledge.


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OfflinePsiloman
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Re: Growing cubensis on a bed of Salvia leaves? [Re: Chemical_Bliss]
    #4369374 - 07/04/05 12:07 PM (18 years, 8 months ago)

I am as heroic as Joxer from Xena!

"Psiloman the Mighty,
climbed on a tree,
whirling in a mushroom daze
he drowned in a cup of tea"

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OfflinePhoenix99
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Re: Growing cubensis on a bed of Salvia leaves? [Re: Psiloman]
    #4372730 - 07/05/05 03:55 PM (18 years, 8 months ago)

Hey don't get so excited about this Psilo. Of course it won't work. It's not a that stupi idea though, since things similar to this happen. I heared some cows I don't know where are fed with fish and they give much fattier milk for example.
It would be nice too mix them togrther, to have them fuck one another. It would be nice to have some geneticalluy midified salvia with the genes of cubensis which produce their psychoactive subsance. Some peyote would fit really nice in this combination too. And this is possible, it just needs a lot of funding and good researchers taking it up.

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OfflinePsiloman
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Re: Growing cubensis on a bed of Salvia leaves? [Re: Phoenix99]
    #4372788 - 07/05/05 04:15 PM (18 years, 8 months ago)

ummm ,wouldnt happen what?

Cubensis on salvia? yes ,thats quite reasonable.Whoever though wants to try cubensis on a peganum harmala substituted substrate could try it.Something interesting might come out,or not.

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OfflineIamthewalrus
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Re: Growing cubensis on a bed of Salvia leaves? [Re: Psiloman]
    #4372815 - 07/05/05 04:21 PM (18 years, 8 months ago)

you seem like a bright guy psiloman...I dunno if its been mentioned but I remember reading it IS possible to make your mushrooms produce dpt by adding something(Forget what now)

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