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i've been offered acid a handfull of times over the years, always accepting, of course. i've also always been on some anti-depressant each time and have not gotten past the simple effects - slight visuals, speedy feeling. i'd suggest buying an extra blotter and taking twice the dosage if you're on a therapeutical amount of the zoloft. i've forgotten already the dosaging with zoloft, if you've been prescribed past the threshold amount, which you have i'm sure, then proceed with taking it 2/1.