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InvisibleWorld Spirit
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Possible Cure For Death Cap Ingestion (Poisoning)
    #3973968 - 03/26/05 10:19 PM (12 years, 7 months ago)



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InvisibleBi0TeK
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Re: Possible Cure For Death Cap Ingestion (Poisoning) [Re: World Spirit]
    #3975355 - 03/27/05 09:04 AM (12 years, 7 months ago)

hospitals have been using milk thistle for mushroom poisoning for quite some time now.

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OfflineToxicManM
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Re: Possible Cure For Death Cap Ingestion (Poisoning) [Re: World Spirit]
    #3975974 - 03/27/05 02:51 PM (12 years, 7 months ago)

Silibinin and Silymarin (the substances believed to be important in milk thistle) have not been approved yet by the appropriate government agencies in the US, so they are not yet in use here. They are in wide use in Europe and are part of the standard treatment for amatoxin poisoning. Poisoning rates in Europe are far higher than the US.

Initial testing has been promising. Definitive studies have not yet been performed. As yet, the evidence is basically anecdotal.

Oral extracts of milk thistle are available in the US, but testing seems to indicate that they are far less effective than intravenous preparations.

Happy mushrooming!


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OfflineMitchnast
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Re: Possible Cure For Death Cap Ingestion (Poisoning) [Re: ToxicMan]
    #3978532 - 03/28/05 01:42 AM (12 years, 7 months ago)

how does it effect opoids?


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InvisibleBolwarra
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Re: Possible Cure For Death Cap Ingestion (Poisoning) [Re: Mitchnast]
    #3979232 - 03/28/05 05:13 AM (12 years, 7 months ago)

that's cool, would be interesting to see some info in future research.

Mitchnast: as far as i can see, this isn't related to opiates. only liver damage caused by a few potent toxins some of which occur in amanita species. but i doubt any work has ever been done on opiate OD and thistle treatments, so who knows.


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OfflineToxicManM
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Re: Possible Cure For Death Cap Ingestion (Poisoning) [Re: Mitchnast]
    #3979851 - 03/28/05 12:42 PM (12 years, 7 months ago)

Mitchnast - I haven't seen anything that mentions any particular usage of milk thistle or extracts relative to opiates. I'm not a pharmacologist, there may be some use.

Bolwarra - You probably already knew this, but the amatoxins also occur in dangerous levels in species of Galerina, Lepiota, and Conocybe. Harmless levels of amatoxins have been found in lots of mushrooms including choice edibles such as Boletus edulis.

Happy mushrooming!


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