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Shrooms does no physical harm to your body what so ever, but if you have latent psychological problems it could trigger those, and also you will come back a changed person, but everything in life changes you in some way, running the stop light today on my way to work changed me today www.erowid.org read it like the bible.
Weed has not long term effects really, unless it gives you lung cancer from smoking it, but thats not proven, you can get other lung illness as well like brochitus just stop smoking it for a bit, or eat it, cannabutter pot cookies are the shit mental effects, none of them are long lasting, if you smoke like everyday then your memory will get effected, youll forget things, or repeat yourself a lot, but again stop smokin for awhile and youll go back to "normal"...then again i think normal is a relative word...once again www.erowid.org all the info youll ever need.
-------------------- The oldest and strongest emotion of man is fear, and the oldest and strongest fear, is fear of the unknown... -H.P. Lovecraft
Both are mainly mental, and in that case completely unique to the individual. Smoke of any kind can cause lung damage, however marijuana has never been proven to cause lung cancer or kill anyone through lung damage, because it is not radioactive and does not mutate the cells like tobacco does. It's not really a huge worry to most people, because not only is marijuana smoke much less harmful than tobacco smoke, you smoke a lot less of it, but if you're worried you can use a vaporizer or make cannabis drinks/ delicacies.
-------------------- So long as you are praised think only that you are not yet on your own path but on that of another.