Home | Community | Message Board
You are not signed in.
Sign In New Account
Forum Index Search Posts Trusted Vendors Highlights Galleries FAQ User List Chat Store Random Growery

Avalon Magic Plants
This site includes paid links. Please support our sponsors.

Mushrooms, Mycology and Psychedelics > Advanced Mycology
Threaded Mode Threaded  Previous topic Previous  View all topics Index  Next topic Next 

Welcome to the Shroomery Message Board! You are experiencing a small sample of what the site has to offer. Please login or register to post messages and view our exclusive members-only content. You'll gain access to additional forums, file attachments, board customizations, encrypted private messages, and much more!

Shop: Original Sensible Seeds High THC Strains   PhytoExtractum Buy Bali Kratom Powder   MagicBag.co Certified Organic All-In-One Grow Bags   Mushroom-Hut Mono Tub Substrate   North Spore Bulk Substrate   Myyco.com Pan Cyan Liquid Culture For Sale   Left Coast Kratom Buy Kratom Extract

Jump to first unread post Pages: | 1 | 2 | 3 | 4 | 5 |  [ show all ]
Some of these posts are very old and might contain outdated information. You may wish to search for newer posts instead.
Re: Increasing alkaloid levels [Re: murderlabz]
    #26405138 -

Thanks murderlabz 🙏 will do.


--------------------
‎שלום וְאור | PEACE & LIGHT

Extras: Filter Print Post Top
Re: Increasing alkaloid levels [Re: murderlabz]
    #26410643 -

murderlabz said:
Psilotyl said:
I’m a little disappointed in Gartz in general. He apparently did so much wierd and cool stuff in Leipzig, and yet documents of it all are scarce. He doesn’t seem like he was particularly concerned with posterity or passing this stuff onward as much as he was experimenting for his own sake. Idk.


Lookup Prof. Dr. Dirk Hoffmeister  he's been doing some killer research related to psilocybin. Too bad it's going to be for big pharma...


Thanks for exposing me to this guy.


--------------------
:sporedrop: :sporedrop: :sporedrop: :sporedrop:

TEK:

_🍄SFF Shoebox Assembly TEK _🍄Bod's easy AF cheapest way to get started by yourself no need for a pressure cooker _🍄How to Keep Those Surface Conditions Super Sexy Tek
_______________________________________

Extras: Filter Print Post Top
Re: Increasing alkaloid levels [Re: HolyBolete]
    #28161047 -

Not to bump an old thread, but I thought there might be something worth noting here. This may sound like a headache, so if you're not in the mood for research, my advice would be to NOT read this next post until you ARE in the right mood. Reading this post may take multiple hours depending on the level of familiarity you have with these topics.

First, allow me to very briefly go over some of the chemicals detected in psilocybin mushrooms, along with some potentially mind-altering notes.

You've all probably read tons of literature on the following compounds, which I will capitalize below, rather than leaving them un-capitalized:

1. Psilocybin
2. Psilocin
3. Baeocystin (Baeocystine)* = misnomer
4. Nor-Baeocystin* = misnomer
5. Aeruginascin
6. Nor-Psilocin

* Note: According to author Paul Stamets, the chemical currently known as baeocystin (baeocystine) was incorrectly named. A misnomer occurred as a result of a mis-identified collection of what was actually Psilocybe cyanescens (and not Psilocybe baeocystis, as was originally published). He proposed cyanescin as the new chemical name, and hinted it could be studied for human therapeutic potential. This would also cause nor-baeocystin to be called nor-cyanescin. See this and fast forward to about 58 minutes through.

See also the important paper titled, Injury-Triggered Blueing Reactions of Psilocybe Magic Mushrooms. Substrates designed to increase psilocybin may also play a significant role in potency and chemical profiles. The third harvested flush of some strains may also play a significant role. As mentioned by others, genetics appear to be the ultimate pathway for altering potency. This requires effort, stamina, and lab gear.

Psilocybin mushrooms also all appear to develop significant quantities of various MAOIs (MonoAmine Oxidase Inhibitors). See this.

See the book called Psychedelics Reimagined by Thomas Lyttle. It includes a section/chapter titled, Psychedelic Monographs and Essays, Volume Six (1993). In it is a page or more about adding dextrose to the substrate (rye in this case) to achieve higher psilocybin content.

However, one mycologist wrote on this site many years ago that this was not the right way to go about it. This particular mycologist said,

Quote:
"I don't see why dextrose would increase psilocybin content. If you really want to increase psilocybin content, add Diammonium Phosphate and non-fat powdered milk to the substrate.  Diammonium Phosphate has the phosphorus needed to make psilocybin, and non-fat powdered milk has the tryptamines."



However, it seems adding tryptamine may also increase psilocybin and psilocin levels.

Jochen Gartz's recipe, as mentioned in previous comments, reciprocally calls for 1/2 pint PF Tek jars: 1/2 - 2/3 cup of vermiculite + 1/8 cup of brown rice powder and (45 milliliters of water with .1 grams of Tryptamine HCL added). Any more than .1 g will cause poorly formed, dwarf-like specimens. However, as experiments in this thread have mentioned, this recipe is now strongly under scrutiny.

As a final stimulating note here, all of the notes provided here require lab gear to confirm these notes or disprove these notes. That lab gear will almost certainly require Liquid Chromatography/Mass Spectrometry. This requires more effort than all members of The Shroomery appear to be willing to put in on this interesting topic. I see a lot of under study, and a massive amount of laziness regarding this topic. If there are literally about 200 species of fungi confirmed for the presence of one or more chemicals relevant to this post, that means someone - or a team - needs to test each species of each relevant genus. Perhaps the person on this resource could lead such an effort.

More For Those Willing To Push The Envelope Of Science:
https://www.agilent.com/cs/library/support/documents/a05296.pdf
https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/617755bc913a74cab06a8a2d/original/rapid-quantification-of-psilocybin-with-reversed-phase-hplc-and-single-wavelength-detection.pdf

Extras: Filter Print Post Top
Re: Increasing alkaloid levels [Re: Thomas Envisio]
    #29292109 -

we need to raise the issue, the whole point is in the selectivity of the substrate)

Extras: Filter Print Post Top
Re: Increasing alkaloid levels [Re: 11.11]
    #29292213 -

11.11 ReverendMyc has done extensive testing with different grain types and a IO Rodeo Colorimeter.

https://www.shroomery.org/forums/showflat.php/Number/28776531/fpart/1/vc/1

It may not be that thread, just search his threads for the thread.

Extras: Filter Print Post Top
Re: Increasing alkaloid levels [Re: DERRAYLD]
    #29292406 -

Yo D, 11.11 is doc smoke in a new sock.


--------------------
🅃🄴🄰🄼 🄸🄷🄾🄿


New to cultivation or the shroomery?  Observe the hitchhiker's guide

The Hitchhiker's Guide to the Shroomery



Smellyhobbit said:
"Wiping a needle with isopropyl after flame sterilization is like shitting after you wipe your ass."

Extras: Filter Print Post Top
Re: Increasing alkaloid levels [Re: Mr Piggy]
    #29292815 -

The reg date would suggest dr smoke was 11.11s puppet.

But yeah, some serious hot takes looking at the post history :facepalm:


--------------------
pan guide and tek index
panaeolus subg. copelandia adv. mycology thread

Does the devil get scared if she dies in her dreams, while the earth burns?

Extras: Filter Print Post Top
Re: Increasing alkaloid levels [Re: tree frog] * 1
    #29292830 -

Dude is getting in the way of my helpful spirit :lol:

Extras: Filter Print Post Top
Re: Повышение уровня [Re: Mr Piggy]
    #29292863 -

Mr Piggy said:
Yo D, 11.11 is doc smoke in a new sock.



I don't smoke in new socks, stop it boys, you've got me confused with someone else!


--------------------
from Russia with love

Extras: Filter Print Post Top
Re: Повышение уровня [Re: 11.11] * 1
    #29292891 -

Please post pictures of your drying rack.

Extras: Filter Print Post Top
Re: Повышение уровня [Re: 11.11]
    #29292899 -

by the way, a few words about the thread that was closed, with my arguments about the significance of bruises at the site of injury, they really can be used to indirectly judge the potential strength of the action and approximate effects (body, mind)


--------------------
from Russia with love

Extras: Filter Print Post Top
Re: Повышение уровня [Re: 11.11]
    #29292901 -

11.11 said:
by the way, a few words about the thread that was closed, with my arguments about the significance of bruises at the site of injury, they really can be used to indirectly judge the potential strength of the action and approximate effects (body, mind)


That's not true.

Extras: Filter Print Post Top
Re: Increasing alkaloid levels [Re: 11.11]
    #29292913 -

Please don't change the post subjects, it might be confusing for people.


--------------------
📨 Journey of a Letter ✉️ the thread about how letters travel, how to address an envelope, and how to expedite delivery 📨📭
☞ Guide to the Shroomery - how to grow shrooms from A to Z guide ☜
If you want to dive in and grow some Pans, this is the place to start! ⥾
🅃 🄴 🄰 🄼    🄲 🄻 🄸 🄽 🄶 🅆 🅁 🄰 🄿

Extras: Filter Print Post Top
Re: Increasing alkaloid levels [Re: Bra] * 2
    #29293067 -

Imagine being so pathetic that you've made puppets for years and have a huge reserve of them, but literally cannot make it past 20 posts without outing yourself.  What a weak and useless trash person.


--------------------
🅃🄴🄰🄼 🄸🄷🄾🄿


New to cultivation or the shroomery?  Observe the hitchhiker's guide

The Hitchhiker's Guide to the Shroomery



Smellyhobbit said:
"Wiping a needle with isopropyl after flame sterilization is like shitting after you wipe your ass."

Extras: Filter Print Post Top
Re: Increasing alkaloid levels [Re: Mr Piggy] * 2
    #29293075 -

Two year old thread bump too.

And I wish the tryptophan and substrate stuff would die.  This was thoroughly debunked and isn't backed up by biology.

Mushrooms make tryptophan via the shikimate pathway.  They don't eat it and turn it into psilocybin.

I am researching this pathway, but odds are there's enough precursors in grains (or manure/strawbased subs for exotics) that there would be no benefit to adding it.  Even in mushrooms such as pans that synthesize a lot more psilocybin.

Additionally, bruising isn't always visible to the naked eye.  As secondary metabolites like melanin can hide bruising that would otherwise be visible too.  Fruits showed minimal bruising under UV pre drying too.



Heavy maoi 'bruising' visible after drying.  Still no blue really.



--------------------
pan guide and tek index
panaeolus subg. copelandia adv. mycology thread

Does the devil get scared if she dies in her dreams, while the earth burns?

Extras: Filter Print Post Top
Re: Increasing alkaloid levels *DELETED* [Re: tree frog]
    #29293112 -

Post deleted by Mr Piggy

Reason for deletion: confirming


--------------------
🅃🄴🄰🄼 🄸🄷🄾🄿


New to cultivation or the shroomery?  Observe the hitchhiker's guide

The Hitchhiker's Guide to the Shroomery



Smellyhobbit said:
"Wiping a needle with isopropyl after flame sterilization is like shitting after you wipe your ass."

Extras: Filter Print Post Top
Re: Increasing alkaloid levels [Re: Mr Piggy]
    #29293240 -

It's settled. Bro.


--------------------
Shrumonoids

Panaeolus Cambodginiensis from Russia
Panaeolus Cyanescens Jamaica from Russia
Goliath.A new greenhouse.Customization

Edited by angamshroom (07/24/25 12:38 PM)

Extras: Filter Print Post Top
Re: Increasing alkaloid levels [Re: angamshroom] * 1
    #29293244 -

May have been a name typo, I'll take that down while I go back and check.


--------------------
🅃🄴🄰🄼 🄸🄷🄾🄿


New to cultivation or the shroomery?  Observe the hitchhiker's guide

The Hitchhiker's Guide to the Shroomery



Smellyhobbit said:
"Wiping a needle with isopropyl after flame sterilization is like shitting after you wipe your ass."

Extras: Filter Print Post Top
Re: Повышение уровня алкалоидов *УДАЛЕНО* [Re: Mr Piggy]
    #29293735 -

Mr Piggy said:
Post deleted by Mr Piggy

Reason for deletion: confirming



holy jesus shit, you still won't calm down?


--------------------
from Russia with love

Extras: Filter Print Post Top
Increasing alkaloid levels [Re: 11.11] * 2
    #29293808 -

Please stop changing the thread name to Russian


--------------------
pan guide and tek index
panaeolus subg. copelandia adv. mycology thread

Does the devil get scared if she dies in her dreams, while the earth burns?

Extras: Filter Print Post Top
Jump to top Pages: | 1 | 2 | 3 | 4 | 5 |  [ show all ]

Shop: Original Sensible Seeds High THC Strains   PhytoExtractum Buy Bali Kratom Powder   MagicBag.co Certified Organic All-In-One Grow Bags   Mushroom-Hut Mono Tub Substrate   North Spore Bulk Substrate   Myyco.com Pan Cyan Liquid Culture For Sale   Left Coast Kratom Buy Kratom Extract

Mushrooms, Mycology and Psychedelics > Advanced Mycology
Threaded Mode Threaded  Previous topic Previous  View all topics Index  Next topic Next 

Similar ThreadsPosterViewsRepliesLast post
* Alkaloid levels in submerged cultures iudexk 1,098 2 11/01/01 12:10 AM
by sylo
* Useful Substrate Supplements
( 1 2 all )		 Humidity 8,747 24 07/20/11 02:10 AM
by RogerRabbit
* Any way to measure alkaloids without a lab? Rockstar69 1,226 7 02/20/05 07:21 AM
by pyronicx
* Culture of C.paspali for alkaloidal production, No Acid talk please! whiterasta 16,787 18 03/18/14 04:39 PM
by Realnuggetz
* A level chemistry - fly agarics Littleman 1,748 7 12/13/06 06:14 PM
by Littleman
* Extra 6 tryptamine alkaloids theshiftingwalls 1,175 2 11/24/03 04:41 PM
by theshiftingwalls
* critical temperatures for alkaloids. uniboner 2,342 8 04/22/05 11:27 AM
by Abermelin
* alkaloid questions... amyloid 849 2 03/11/03 10:32 AM
by zeta

Extra information
You cannot start new topics / You cannot reply to topics
HTML is disabled / BBCode is enabled
Moderator: RogerRabbit, cronicr, Stipe-n Cap, Pastywhyte, bodhisatta
13,291 topic views. 0 members, 2 guests and 4 web crawlers are browsing this forum.
[ Show Images Only | Sort by Score | Print Topic ]
Search this thread:

Copyright 1997-2026 Mind Media. Some rights reserved.

Generated in 0.038 seconds spending 0.009 seconds on 17 queries.