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Offlinemrvanhalen
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serotonin
    #3510340 - 12/16/04 08:28 PM (11 years, 11 months ago)

my buddy has a serotonin defficiency and is on serotonin pills for mood or something... we eats shrooms occasionally, would a serotonin defficiency give him a different trip than me?


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InvisiblesuiM
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Re: serotonin [Re: mrvanhalen]
    #3510420 - 12/16/04 08:46 PM (11 years, 11 months ago)

I have no idea but im interested, find out and post it.


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Invisiblenewusername222
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Re: serotonin [Re: mrvanhalen]
    #3510459 - 12/16/04 08:56 PM (11 years, 11 months ago)

Depends on what's causing the deficiency. What type of pills is he taking?


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Invisibledblaney
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Re: serotonin [Re: newusername222]
    #3510485 - 12/16/04 09:01 PM (11 years, 11 months ago)

Well if it's a deficiency, then most likely he's getting supplemental serotonin either as 5-HTP or L-Tryptophan. This is just speculation, however. But as I understand it, it could either cause a much more powerful trip, or a much weaker trip. If he takes serotonin on the day he trips, theoretically it would make sense that he would trip less, since I believe serotonin would be the more powerful of the two in competition for the 5-HT1 and 5-HT2 receptors.


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Making the noise "penicillin" is no substitute for actually taking penicillin.

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InvisibleKoala Koolio
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Re: serotonin [Re: dblaney]
    #3510495 - 12/16/04 09:03 PM (11 years, 11 months ago)

Yeah, I don't know enough to tell what exactly would happen, but I definately believe that if his serotonin system is "abnormal" trips would be effected.


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Offlinemrvanhalen
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Re: serotonin [Re: Koala Koolio]
    #3510520 - 12/16/04 09:09 PM (11 years, 11 months ago)

he takes one pill of Venlafaxine HCL, i think effexor. he was depressed and stressed before so they put him on them. all i know is he gets drunk off one beer now


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Invisiblenewusername222
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Re: serotonin [Re: mrvanhalen]
    #3510668 - 12/16/04 09:42 PM (11 years, 11 months ago)

That's a Serotonin and norepinephrine reuptake inhibitor. Psilocybin works by blocking the release of serotonin from certain neurons in the brain. SO, you have a decrease in serotonin being released, and you have reuptake being inhibited. He'll probably still get off, but not as heavily.


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Invisibledblaney
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Re: serotonin [Re: newusername222]
    #3510778 - 12/16/04 10:02 PM (11 years, 11 months ago)

Supernova's on the money


--------------------
"What is in us that turns a deaf ear to the cries of human suffering?"

"Belief is a beautiful armor
But makes for the heaviest sword"
- John Mayer

Making the noise "penicillin" is no substitute for actually taking penicillin.

"This country, with its institutions, belongs to the people who inhabit it. Whenever they shall grow weary of the existing government, they can exercise their constitutional right of amending it, or their revolutionary right to dismember or overthrow it." -Abraham Lincoln


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Invisiblenewusername222
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Re: serotonin [Re: dblaney]
    #3510825 - 12/16/04 10:11 PM (11 years, 11 months ago)

yeah, and by the way, if he's depressed, psilocybin may increase his depression by keeping the happy stuff (serotonin) out of his system. buyer beware.


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Invisibledblaney
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Re: serotonin [Re: newusername222]
    #3510856 - 12/16/04 10:16 PM (11 years, 11 months ago)

It's possible, but as far as I know that has yet to be proven or even tested. Most likely, I would think, it would just be temporarily displaced, but I'm not an expert.


--------------------
"What is in us that turns a deaf ear to the cries of human suffering?"

"Belief is a beautiful armor
But makes for the heaviest sword"
- John Mayer

Making the noise "penicillin" is no substitute for actually taking penicillin.

"This country, with its institutions, belongs to the people who inhabit it. Whenever they shall grow weary of the existing government, they can exercise their constitutional right of amending it, or their revolutionary right to dismember or overthrow it." -Abraham Lincoln


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Invisiblenewusername222
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Re: serotonin [Re: dblaney]
    #3510869 - 12/16/04 10:18 PM (11 years, 11 months ago)

I'm not an expert either. Just seems logical though. Not that it would be a permanent thing, but a depressed person tripping probably isn't a good thing anyway absent some good controls being in place.


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OfflineSoftRat
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Re: serotonin [Re: mrvanhalen]
    #3512064 - 12/17/04 02:57 AM (11 years, 11 months ago)

Drug that increase seotonin levels in the brain can be dangerous in combination with psychedellics.


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Invisibledblaney
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Re: serotonin [Re: newusername222]
    #3512338 - 12/17/04 06:21 AM (11 years, 11 months ago)

Quote:

supernova said:
I'm not an expert either. Just seems logical though. Not that it would be a permanent thing, but a depressed person tripping probably isn't a good thing anyway absent some good controls being in place.




Very true...it is good advice to discontinue any and all medication for at least two weeks or so prior to a psychedelic trip.


--------------------
"What is in us that turns a deaf ear to the cries of human suffering?"

"Belief is a beautiful armor
But makes for the heaviest sword"
- John Mayer

Making the noise "penicillin" is no substitute for actually taking penicillin.

"This country, with its institutions, belongs to the people who inhabit it. Whenever they shall grow weary of the existing government, they can exercise their constitutional right of amending it, or their revolutionary right to dismember or overthrow it." -Abraham Lincoln


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Offlinecb9fl
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Re: serotonin [Re: dblaney]
    #3512768 - 12/17/04 10:45 AM (11 years, 11 months ago)

Unless of course you're insulin dependent. I think that would be somewhat of a bad thing.


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Offlinemrvanhalen
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Re: serotonin [Re: cb9fl]
    #3513890 - 12/17/04 03:54 PM (11 years, 11 months ago)

one time we were trippin he was staring at the wall let out a tear and he told me how happy he was, so he never had any depression problems on mushrooms. what would happen if someone took like five of those serotonin pills?


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Invisibledblaney
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Re: serotonin [Re: mrvanhalen]
    #3514349 - 12/17/04 05:56 PM (11 years, 11 months ago)

Well depends...if by 'those serotonin pills' you are referring to Venlafaxine, and on how large each pill was. You probably won't OD on it, but it wouldn't be good. You would probably be very sleepy. If it was a large enough dose, then there is an increased risk for things like convulsions, seizures, coma, vertigo, etc. If you just wanna get high off it...don't...there are better things.


--------------------
"What is in us that turns a deaf ear to the cries of human suffering?"

"Belief is a beautiful armor
But makes for the heaviest sword"
- John Mayer

Making the noise "penicillin" is no substitute for actually taking penicillin.

"This country, with its institutions, belongs to the people who inhabit it. Whenever they shall grow weary of the existing government, they can exercise their constitutional right of amending it, or their revolutionary right to dismember or overthrow it." -Abraham Lincoln


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