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Because of the extremely low active dose of LSD, it is possible for LSD to absorb through your skin into your bloodstream, in which case you would proceed to trip. However, psilocybin requires a MUCH higher dose for you to actually feel anything, so while you may absorb VERY minute amounts of psilocybin/psilocin (especially since you're not handling pure material) through your skin, it is not possible for you to feel any difference after handling mushrooms.
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