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Hardani



Registered: 04/01/20
Posts: 165
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Amphetamines and microdosing shrooms?
#28676466 - 02/26/24 02:16 AM (3 months, 28 days ago) |
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Hello everyone Im currently on lisdexamfetamin mesilate (a stimulant like Ritalin for adhd but with much longer halflife) and i take 1/4 of a 50mg pill a day and i have a bunch of shroom microdosing capsules. So is it safe to take them to gether? Anybody have any experience?
Edited by Hardani (02/26/24 01:47 PM)
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Northerner
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Re: Amphetamines and microdosing shrooms? [Re: Hardani]
#28681993 - 02/29/24 10:10 PM (3 months, 24 days ago) |
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Physically it's safe. There's very few things contraindicated with mushrooms.
Higher doses of both together could lead to difficult psychological situations, with some people.
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The nearest we ever come to knowing truth is when we are witness to paradox.
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Hardani



Registered: 04/01/20
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Re: Amphetamines and microdosing shrooms? [Re: Northerner]
#28683579 - 03/02/24 07:47 AM (3 months, 23 days ago) |
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Thank you. Have you ever tried this combo? If yes can you tell me what should I expect?
-------------------- تو مگو همه به جنگند و ز صلح من چه آید تو یکی نهای هزاری تو چراغ خود برافروز -------------------------------- یک آدم چیه به غیر از مجموع خاطراتش؟ پر زندگی کن --------------------------------
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M1c33L1um
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Re: Amphetamines and microdosing shrooms? [Re: Hardani]
#28711564 - 03/24/24 11:48 AM (3 months, 1 day ago) |
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I have never taken them together but I am experienced w/ both Amphetamines and Shrooms. lisdexamfetamin mesilate is actually a true Amphetamine and has no relation to Ritalin. Ritalin is a stimulant but is unrelated to Amphetamines. lisdexamfetamin mesilate turns into Dexamphetamine after you take it and it is roughly equivalent to 20 mg Dexamphetamine. In General, one would not take shrooms w/ a stimulant because it can increase anxiety as Northerner mentioned but true amphetamines (such as lisdexamfetamin mesilate) have many positive aspects to them that can add greatly to the Psychedelic experience. I think that 20mg of Dextroamphetamine may be to much to take on a full Shroom trip - but if microdosing, it should be fine. Also, if you have been taking the LM for any length of time, your body is probably used to the effects and there should be very little negative drug interaction.
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lunawillow
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Re: Amphetamines and microdosing shrooms? [Re: Hardani]
#28725084 - 04/03/24 09:20 PM (2 months, 21 days ago) |
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I take a 60 mg capsule of Vyvanse (the generic name is Lisdexamfetamine) daily. Although I started my journey with mushrooms in the last few months (my first trip was in January), I’ve never had an issue taking the meds with mushrooms, macrodose or microdose. I skipped the Vyvanse two times that I’ve taken a macrodose (3-4g) yo compare and didn’t notice a difference.
Good luck!
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nooneman


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Re: Amphetamines and microdosing shrooms? [Re: Hardani]
#28725149 - 04/03/24 10:35 PM (2 months, 21 days ago) |
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It's safe. I've combined mushrooms and stimulants, it's a fine combo, although it does significantly alter the experience.
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CiscoHouston
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Re: Amphetamines and microdosing shrooms? [Re: nooneman]
#28757176 - 05/01/24 01:14 AM (1 month, 25 days ago) |
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On two occasions I've taken 15mg of adderall about 1-2 hrs into a light mushroom experience (more than a microdose but not quite level 1). I enjoyed it, I thought the motivating energetic feeling of the adderall mixed nicely with the effects of the mushrooms.
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CosmicIguana
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Re: Amphetamines and microdosing shrooms? [Re: CiscoHouston]
#28757232 - 05/01/24 03:47 AM (1 month, 25 days ago) |
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Using sweaty meths back in the days completely cancelled effects for me. Also mieth is very bad, you stink with meth mouth and meth feet and fungus everywhere.. Not a good experience imo
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ParaSamGate
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Re: Amphetamines and microdosing shrooms? [Re: CosmicIguana]
#28766286 - 05/08/24 09:36 AM (1 month, 18 days ago) |
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The combination of as-prescribed amphetamines and low dose shrooms is unlikely to alter the relatively high safety profile of these drugs. Amphetamines and psilocin result in elevated dopamine and norepinephrine levels, and it’s possible that amphetamines also result in higher extracellular seratonin (which is substantially elevated by psilocin). Which means they likely are active at the related receptors, though the elevated chemicals could be the result of different actions and there are different types of receptors for each of these neurotransmitters so the drugs aren’t necessarily elevating the levels by identical mechanisms. Neither prescribed doses of amphetamines nor micro doses of psilocin cause major increases in the neurotransmitters, so if there is an additive effect, it’s likely to be quantitatively and subjectively mild. It’s also theoretically possible that the action of one could interfere with the action of the other at one or more receptor sites, which could also alter the subjective experience.
I wouldn’t worry bout it. I’ve taken amphetamines for years on an as-needed basis for ADHD, and never noticed any significant alteration in subjective experience except that co-administration seems to make a low dose mushroom experience feel a bit more pleasant. If I’m going to take a large dose of a psychedelic, I will skip the amphetamines for a day or two in advance, mostly because I don’t want anything onboard that could alter the subjective experience I’m going for.
Back in the day, I knew people who routinely mixed meth and acid, generally in large quantities. I didn’t enjoy the combination and I didn’t enjoy being around those folks at all.
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The Blind Ass
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Re: Amphetamines and microdosing shrooms? [Re: ParaSamGate] 1
#28766442 - 05/08/24 11:29 AM (1 month, 18 days ago) |
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Due to conditioning & the habit-/-dependency causing nature of psychostimulants I prefer not to take any in tandem with mushrooms. Even if while I already have something on board. Otherwise, there’s a tendency for the mushroom experience to be blunted, in addition to a stimulatory based dopaminergic pleasure component to the experience; one that I personally find to be a bit too habit reinforcing.
In other words, I find it taints future experiences. Same thing goes with benzodiazepines, as well as with opiates, too.
Although, at 20 y.o. I did not mind mixing & matching substances of greatly differing classes, be it as prescribed & sometimes not as rx’d. As Rx’d, wrt methylphenidate 2 x 5mg daily [<~6 months on that dose] , I did not experience many negative side effects from combining the above with psy-mushrooms. Typical results as can be imagined from combining a classical stimulant with a classical psychedelic; slightly elevated heart rate, BP, GI-sensitivity, trouble sleeping afterwards, etc. <~ The particulars of which naturally corresponded with specific dosage taken, and all of the other relevant contributing factors, like my general health, mood, sleep, stress, eating, bathroom cycles, etc.
-------------------- Give me Liberty caps -or- give me Death caps
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earnest
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Re: Amphetamines and microdosing shrooms? [Re: The Blind Ass] 2
#28776676 - 05/16/24 05:28 PM (1 month, 9 days ago) |
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I take vyvanse and periodically microdose semi regularly (4 days on, 3 off)
For me, microdosing and ADHD meds work well together. Better connections with others at work and find I'm more creative at work.
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Stevo71
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Re: Amphetamines and microdosing shrooms? [Re: earnest]
#28787170 - 05/25/24 08:28 AM (1 month, 1 day ago) |
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To add to the above I take 70mg of Vyvanse daily plus 15mg of dexamphetamine sulfate later in the day to top me up which is a lot of amphetamines.
I started microdosing mushrooms back in March and have been experimenting with the dosage since to see what works best and am now taking 0.2g on a 8 days on 2 days off cycle and am benefitting more than I ever expected I would. I have also introduced a capsule of Lion's Mane each day but am unsure of the effects of that so far as it has only been a few days since I started them. Plus the Psilocybin capsules I make up myself from ground dried shrooms (combination of PE and Kape) while the Lion's Mane is bought from a reputable online store.
I don't know if the shrooms combined with the amphetamines is problematic or not but I don't think it is. However my BP has gotten dangerously high lately but that would more than likely be from the amphetamine usage rather than the shrooms as from what I have read the shrooms tend to help lower blood pressure rather than raise it.
To be clear I have early onset hypertension that runs in my paternal side and I have been getting treatment for it since my mid 20's (I am in my 50's now) along with a history of erratic readings. There also may be other factors at play for the recent spike in BP (readings of 180 over 100 and so on) and I am currently undergoing some tests to see what may be causing it including an MRI I have booked for two weeks time. Further to that I am experiencing a lot of stressful situations in my personal life right now such as a dying mother and an arsehole landlord to name a few so they also would likely be factors even though the microdosing is doing wonders for my ability to cope with stress. Oh and just to put the icing on the cake I am also being investigated for Parkinson's Disease.
I know that is a lot and that it may not have that much relevance to the topic but I thought it may be worth sharing as I have considered that the recent microdosing and the amphetamines may be at the root of the spikes to my blood pressure and although I am still unsure I don't think it is the former but could well have something to do with the latter. Other than that I find no other issues combining the two but do find that since I started microdosing the feelings of anxiety that the amphetamines sometimes produced have all but gone.
-------------------- “Today a young man on acid realized that all matter is merely energy condensed to a slow vibration, that we are all one consciousness experiencing itself subjectively, there is no such thing as death, life is only a dream, and we are the imagination of ourselves. Here's Tom with the weather.”
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Syntex
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Re: Amphetamines and microdosing shrooms? [Re: Hardani] 1
#28804672 - 06/08/24 04:42 AM (18 days, 10 hours ago) |
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I've used meth and dexies while on trips of all different psychedelics and the biggest effect was how much it dulled the trip. Almost in the same way a Xanax would.
It's safe but I would skip your daily dose (if you can) so you can get the full enjoyment out of your trip.
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Thessaliad
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Re: Amphetamines and microdosing shrooms? [Re: Syntex]
#28816759 - 06/17/24 07:52 PM (8 days, 19 hours ago) |
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As a person with ADHD, I have found that microdosing has allowed me to lower my overall stimulant dose, which has saved me from convos with my prescriber as to why I might like a higher dose of stimulants.
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